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Humanity is facing one of the greatest challenges ever. Climate change and global warming is a great risk and our consumption and dependency of fossil fuel are important causes of this accelerating issue. My thesis aims to design an entry for the professional debate about what urban areas in a fossil free future might be like. I’m investigating how an urban environment that requires as little tra

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In this 5th version of the European LeukemiaNet guidance for adult patients, there are important changes in several areas of management based on evidence available since 2020, including the World Health Organisation’s reclassification of CML as a biphasic disease. Previous advice to switch the tyrosine kinase inhibitor (TKI) on failure of molecular milestones, is modified to better account for ind

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The modelling of filtered chemical source terms remains a fundamental challenges for large eddy simulation (LES) of reacting flows, such as combustion. This study investigates various scale similarity models for predicting filtered reaction rates. The theoretical foundation of scale similarity models is reviewed, and several extensions and generalisations are proposed. These include the distinctio

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This article analyses how a newly established set of actors – online brokerage firms (OBFs) – sought to popularise stock trading among the Swedish populace in the late 1990s. During this period, internet usage took off and stock markets surged rapidly up until the dotcom bubble burst in 2000. Sweden was at the forefront of both these international developments, and we analyse the intimate connecti

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OBJECTIVES: Asphalt is frequently used as road pavement and consists of bitumen as a binder, and fillers. Bitumen consists of a complex mixture of hydrocarbons, where a minor component is polycyclic aromatic hydrocarbons (PAHs). Many PAHs are classified as carcinogenic to humans. Bitumen fumes from road paving have been classified as possibly carcinogenic. Paving and milling are open processes gen

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We study Frege proofs using depth-d Boolean formulas for the Tseitin contradiction on n \times n grids. We prove that if each line in the proof is of size M, then the number of lines is exponential in n/(log M)O(d). This strengthens a recent result of Pitassi, Ramakrishman, and Tan [2022 IEEE 62nd Annual Symposium on Foundations of Computer Science, 2022, pp. 445-456]. The key technical step is a

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The chemical industry, essential to economic growth and innovation, faces critical environmental sustainability challenges, notably pollution, emissions, and intensive resource use. Motivated by the need for practical tools to address these issues, this research develops a structured, comprehensive framework to assess and enhance environmental sustainability within the chemical sector. The framewo

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The illicit trafficking of cultural heritage represents a significant global challenge, exacerbated by digital technologies that facilitate unauthorised trade while offering new protection opportunities. The ANCHISE project addresses these challenges through a suite of six innovative, complementary tools designed to enhance the detection, prevention, and investigation of cultural property traffick

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Background The fundamental problem with the pavement marking letter design is dealing with the phenomenon of image distortion by perspective. Because there has been a lack of a systematic way to deal with the problem on Korean pavement marking letters, the outputs have been determined by the installer's subjective design judgement. Ultimately, this causes low legibility. The purpose of this study

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Transitioning towards a circular economy, where the existing building stock is more efficiently used, would significantly reduce material and energy use, emissions, and waste from the built environment sector. This study focuses on exploring what conditions are needed for circularity by imagining preferable circular futures for a 2035 timeframe and understanding the required actions to achieve the

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This paper presents a search for a new Z′ resonance decaying into a pair of dark quarks which hadronise into dark hadrons before promptly decaying back as Standard Model particles. This analysis is based on proton-proton collision data recorded at s = 13 TeV with the ATLAS detector at the Large Hadron Collider between 2015 and 2018, corresponding to an integrated luminosity of 139 fb−1. After sele

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The problem of approximate joint eigen-decomposition of a collection of matrices arises in a number of diverse engineering and signal processing problems. This problem is usually cast as an optimization problem, and it is the main goal of this publication to provide a theoretical study of the corresponding objective-functional. As our main result, we prove that this functional tends to infinity in

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John Maynard Keynes was nominated for the Nobel Peace Prize in the 1920s for writing “The Economic Consequences of the Peace”. Yet, despite being highly ranked by the advisor of the Nobel Committee and placed on the shortlist, he did not win. This column brings out previously unused archival material from the Nobel Committee in Oslo to explore why. The Committee tended to withhold the Prize when c

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Bifunctional DNA glycosylases employ an active site lysine or the N-terminus to form a Schiff base with an abasic (AP) site base excision repair intermediate. For 8-oxoguanine DNA glycosylase 1 (OGG1), cleaving this reversible structure is the rate-determining step in the initiation of 8-oxoguanine (8-oxoG) repair in DNA. Evolution has led OGG1 to use a product-assisted catalysis approach, where t

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With this audio paper, our aim is to explore the connection between sound and democracy. Recognizing the multifaceted nature of this field, we approach it through the notion of care and an empirical analysis of the democratic implications of trying to regulate sound in public spaces. We examine ISO standards as one example of the many attempts to control sound in both public and private spaces. St

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In this project I investigate how architecture can give form to an institution that creates the conditions for negotiation between competing narratives. It is situated at Sillhovstomten, the contested site behind the Nationalmuseum in central Stockholm. The failed Nobel Center proposal on this site revealed that it is not an empty void awaiting to be filled, but a place where different political,

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Background: Dietary management of phenylketonuria (PKU) focuses on restricting phenylalanine (Phe) intake. The European PKU guidelines and the PKU Dietary Handbook recommend a simplified PKU diet, allowing unrestricted consumption of many low-Phe foods, called free foods. While this approach may reduce the treatment burden for patients, its implementation varies. This study investigated practi