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Chronic lung diseases (CLDs), such as chronic obstructive pulmonary disease, interstitial lung disease, and lung cancer, are among the leading causes of morbidity globally and impose major health and financial burdens on patients and society. Effective treatments are scarce, and relevant human model systems to effectively study CLD pathomechanisms and thus discover and validate potential new targe
GAD65Ab and ICA512Ab are strongly associated with insulin-dependent (Type 1) diabetes mellitus. A novel, simple radio-antigen binding assay with microSepharose conjugated with monoclonal antibodies specific for human immunoglobulin light chains was developed to provide diagnostic sensitivity and specificity of GAD65Ab and ICA512Ab for Type 1 diabetes. The Receiver Operating Characteristic (ROC) cu
Intersectionality theory can contribute to epidemiology and public health by furthering understanding of power dynamics driving production of health disparities, and increasing knowledge about heterogeneities within, and overlap between, social categories. Drawing on McCall, we relate the first of these potential contributions to categorical intersectionality and the second to anti-categorical int
The overall aim of this thesis was to investigate formal care and services at home, regarding structure, process, and outcomes, for persons with dementia (aged 65+ years) at risk of nursing home admission. Availability and utilization of formal care and services at home for persons with dementia, from diagnosis to end-of-life stage, in eight European countries was described in study I. A mapping f
Accurate and efficient evaluation of the stored energy is essential for Q-factors, physical bounds, and antenna current optimization. Here, it is shown that the stored energy can be estimated from quadratic forms based on a state-space representation derived from the electric and magnetic field integral equations. The derived expressions are valid for small antennas embedded in temporally dispersi
The way we frame a given problem structures the content that is brought into focus and thus the kinds of practical steps seen as necessary to alleviate it. In this article, I interrogate two competing partial framings implicated in ongoing controversy over mangrove destruction in Vikhroli East, Mumbai, which have precluded integrated conservation and development. I interrogate the competing frames
Energies, transition rates, line strengths and lifetimes have been computed for all levels of the 4p 6 and 4p 54d configurations of W38+ by using the multi-configuration Dirac-Hartree-Fock (MCDHF) method as well as relativistic many-body perturbation theory. We investigate systematically correlation, relativistic and quantum electro-dynamical (QED) effects of different properties, including excita
AIMS: Pretreatment of patients with ST-elevation myocardial infarction (STEMI) with P2Y12 receptor antagonists is supported by guidelines and is a common practice despite the lack of definite evidence for its benefit. METHODS AND RESULTS: Using data from the Swedish Coronary Angiography and Angioplasty Registry on procedures between 2005 and 2016, we stratified all patients who underwent primary p
The interest of in vivo measurements of fat has increased over the years due to the increasing prevalence of obesity and obesity-related conditions such as diabetes, cardiovascular disease, and fatty liver. The relationship between the accumulation of adipose tissue within the different depots and organs of the body, and the risk of developing numerous diseases, has been investigated and establish
Background and study aims : Capsule endoscopy (CE) is invaluable for minimally invasive endoscopy of the gastrointestinal tract; however, several technological limitations remain including lack of reliable lesion localization. We present an approach to 3D reconstruction and localization using visual information from 2D CE images.Patients and methods : Colored thumbtacks were secured in rows to the
This paper is partly a summary of the book ‘From a grain of salt to the ribosome’ [1], with extension on some points. Sometimes the developments in science may be very rapid and not fully appreciated at all corners of the scientific society. Harry Clary Jones was a well-known chemist at Johns Hopkins University at the turn of the previous century. He had, in his earlier days, spent time in the lab
To contribute to contemporary rural development debates, the present thesis conducts a contextual analysis of rural development using Kenya as a case study from the colonial era to today. To perform the analysis, two critical trends in rural Africa are focused on: socioeconomic differentiation and rural income diversification, with a particular focus on large-scale farm employment. By pointing to
Modern health care requires a proactive and individualized response to diseases, combining precision diagnosis and personalized treatment. Accordingly, the approach to patients with allergic diseases encompasses novel developments in the area of personalized medicine, disease phenotyping and endotyping, and the development and application of reliable biomarkers. A detailed clinical history and phy
Purpose - The purpose of this paper is to further build up the knowledge about reasons for small and mid-sized enterprises (SMEs) to adopt open source enterprise resource planning (ERP) systems. Design/methodology/approach - The paper presents and analyses findings in articles about proprietary ERPs and open source ERPs. In addition, a limited investigation of the distribution channel SourceForge
