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Effective treatment of bleeding episodes in hemophilia with high titer inhibitors (HTI) remains a challenge, despite the fact that the therapeutic armamentarium has expanded considerably over the past few years. Treatment safety has improved with the availability of porcine factor VIII (FVIII) and bypassing products such as recombinant factor VIIa (rFVIIa), and plasma-derived activated Prothrombin
In this paper a new perspective on modeling of transient phenomena in the context of sinusoidal audio modeling and coding is presented. In our approach the task of finding time-varying amplitudes for sinusoidal models is viewed as an AM demodulation problem. A general perfect reconstruction framework for amplitude modulated sinusoids is introduced and model reductions lead to a model for audio com
Intumescent coatings are increasingly used as a method of passive fire protection on steel constructions. By forming a carbon network and releasing a blowing agent, the thin intumescent film swells 100-fold at elevated temperatures. The highly insulating foam effectively prevents the load bearing steel from reaching its critical temperature at which it looses its mechanical properties and collapse
Background. To further improve the outcome of clinical islet transplantation analysis of the impact of donor- and process-related factors could be of great importance. Materials and Methods. Thirty-eight consecutive clinical islet transplantations were performed with consecutive islet isolations. Univariate analysis for donor- and isolation-related variables were correlated with recipient C-peptid
AIMS: Several cardiovascular disorders (CVDs) are strongly associated with socioeconomic disparities and neighbourhood deprivation. However, no study has determined whether neighbourhood deprivation is associated with atrial fibrillation (AF). We aimed to determine whether there is an association between neighbourhood deprivation and hospitalization for AF.METHODS AND RESULTS: The entire Swedish p
This review article provides an overview of the evidence that links exercise and sports participation to physical and psychological well-being among people with spinal cord injury. Two aspects of physical well-being are examined, including the prevention of chronic disease and the promotion of physical fitness. Multiple aspect's of psychosocial well-being are discussed, including mental health, so
Architects have a key role to play when it comes to the design of future low-energy (solar) buildings. Proper design tools and working methods could help architects in the design process. In order to identify barriers of existing tools and methods for solar design, needs of architects for improved tools, and to gain an insight into architects’ methods of working during the design process, an inter
This paper provides a general framework for electromagnetic (EM) modeling, sensitivity analysis, computation, and measurements regarding the wave propagation characteristics of high-voltage direct-current (HVDC) power cables. The modeling is motivated by the potential use with transient analysis, partial-discharge measurements, fault localization and monitoring, and is focused on very long (10 km
Rarely does the death of animals cause conflict between governments. However, the killing of some animals, such as seals, wolves, and other exotic wildlife, can cause heated conflict over whether the act of killing is itself justifiable.This paper provides an overview of a recent disagreement along these lines – between the EU and Sweden over the management of wolves. It juxtaposes the recent poli
A continuum model of paperboard material possessing a high degree of anisotropy is established. To handle the anisotropy, three vectors are introduced which phenomenologically represent the preferred directions of the material. The in-plane director vectors deform as line segments and the out-of-plane direction deforms as a normal vector. This allows for a decoupling of the in-plane and the out-of
Popular Abstract in Swedish Biotekniska läkemedel blir allt vanligare och behandlar några av våra viktigaste sjukdomar. Några exempel är insulin för diabetes, tillväxthormon, vacciner, och antikroppar som används i behandling av bland annat cancer, rheumatism och mag- tarmsjukdomar. Dessa läkemedel är proteiner eller peptider som tillverkas i jäst eller djurceller och sedan måste utvinnas ur celleTo design efficient and safe biopharmaceutical production processes, understanding the process and how it is affected by changes in the process conditions is essential. Experimental data form the basis of this understanding which can be enhanced by modeling and simulations of the physical and chemical processes known to control the process. This thesis describes modeling of preparative chromatogra
The availability of three-dimensional structures of proteins has provided enormous insight into the detailed molecular machinery of the living cell. Since the late 1950s and early 1960s, experimental methods for deriving protein structures have contributed more than 30,000 entries to the Protein Data Bank, representing the collected knowledge of protein and other macromolecular structures. However
In the autumn of 2011, the course “The City: Boundary Transgressions and Visual Expressions” was given for the first time. Formally placed at the Division of Art History and Visual Studies, the course was a collaboration with the Division of Social Anthropology and was directed towards students from a range of disciplines within the fields of the humanities and social sciences. The course include
