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Background-beta-Adrenergic stimulation is the main trigger for cardiac events in type 1 long-QT syndrome (LQT1). We evaluated a possible association between ion channel response to beta-adrenergic stimulation and clinical response to beta-blocker therapy according to mutation location. Methods and Results-The study sample comprised 860 patients with genetically confirmed mutations in the KCNQ1 cha
The discipline of epidemiology, which holds major influence on public health policy as well as on clinical medical practice, has in recent decades to a large extent been concerned with the identification of factors and markers of risk for disease. Much health information and intervention is thus informed by a wealth of studies on a variety of risk factors, of which the individual is encouraged to
The overarching aim of this thesis was to contribute to the existing knowledge on the use of assistive devices in everyday life, by adding the perspective of very old single living people in a European context, namely Latvia and Sweden. The aim was to investigate the socio-demographics and environmental and health aspects that impact on device use in the two national contexts. A further aim was to
We describe quantum-size and binding-site effects on the chemical and local field enhancement mechanisms of surface-enhanced resonance Raman scattering (SERRS), in which the pyridine molecule is adsorbed on one of the vertices of the Ag-20 tetrahedron. We first investigated the influence of the binding site on normal Raman scattering (NRS) and excited state properties of optical absorption spectro
This paper presents the development of an experimentally validated model that mechanistically comprehends the complex interaction between the gas-phase fluid dynamics, the mass transport of individual species, and the heterogeneous gas-surface reaction mechanism in a continuous cross-flow atomic layer deposition (ALD) reactor. The developed ALD gas-surface reaction mechanism, purely based on conse
The aim of this thesis was to explore and gain deeper insight into and understanding of mobility in public environments for people with acquired cognitive functional limitations (target group of this thesis) and of reasons why some of them do not use public transport. Using an explorative approach, the target group’s mobility was firstly discussed by experts in focus group interviews. Secondly the
Urban green infrastructure (UGI) is gaining popularity for disaster risk reduction and climate change adaptation in urban contexts, but dense development obstructs the realisation of large-scale greening measures. This thesis investigates the potential of small-scale, site-specific urban greening in a residential area in Cologne, Germany, to improve ecosystem service supply. The objective is to as
This thesis aims to investigate the newly emerging phenomenon in the environmental justice sphere – namely, the weaponisation of art by climate activists for the purpose of attracting attention to specific demands held. These attacks materialise in the form of organised acts wherein tactics entailing vandalism are enacted by a climate activist group. With the commencement of this climate movement
Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improvi
Objective: The overlap of normal and abnormal personality and personality disorders was found on facet and domain level, but only a few studies assessed the higher order joint structure. In this study, the Personality Inventory for the DSM-5 (PID-5-100 item form) and the IPIP-NEO-120 are assessed in their internal consistency, convergent and discriminant validity and their joint structure, modelle
This thesis addresses the complexities of the situation of the Roma in Romania and Spain and the challenges of including isolated groups in society. The main texts used for comparison come from the Council of Europe’s expert bodies: the European Commission Against Racism and Intolerance (ECRI), the Advisory Committee (ACFC) under the Framework Convention for the Protection of National Minorities (
Title: Are K2 guidelines sufficient and credible for credit assessments? Course: BUSN69 Degree Project – Master of Accounting and Auditing Authors: Ali Mansour Firouz & Sina Attaran Advisor: Dr. Amanda Tan-Sonnerfeldt Five key words: Credit assessment, Financial statements, K2 guidelines, Banks, Auditing Purpose: To what degree do K2 guidelines affect the usefulness of the financial report
This research shows the impact of credit rating change (thereafter CRC) announcements on the combined entities following mergers and acquisitions. In looking at the effect of CRC announcements on share prices, we measure the level of influence that a credit upgrade or downgrade has on the equity value of firms. Existing literature disputes the applicability of share price as a measure of value cre
Nowadays, innovation and technological development are considered as crucial for the development and economic growth of regions and nations. Knowledge interactions hold a central position in the innovation process. In line with this, researchers as well as politicians emphasize that knowledge interactions need to be facilitated. This approach has been adapted to the cross-border regional context a
Syftet med uppsatsen är att beskriva och analysera välkända strategimodellers applikationsförmåga för de specifika förutsättningar som tjänsteföretag inom storhushåll verkar inom. Metoden som vi valt är kvalitativ och materialet som används tar sin utgångspunkt i sekundärdata i form av offentliga och institutionella källor från kända strategiforskare och branschspecialister. Uppsatsen utgår teorim
This thesis is concerned with history within Nick Clegg’s and Nigel Farage’s political discourse during the six months leading up to the 2016 referendum on the United Kingdom’s membership in the European Union. Using Thematic Analysis combined with Klas-Göran Karlsson’s typology of the use of history, Jörn Rüsen’s typology of historical narrative and drawing on the theoretical framework of histori
Transgender persons experience a disproportionate representation in adverse mental health conditions globally. In Sweden there are tangible efforts to improving mental healthcare overall, but as a minority population, transgender persons still struggle with meeting their mental healthcare needs. While social factors such as stigma and discrimination act as catalysts for this burden, there is an ab
Most of classic psychedelic literature indicate its potential benefit to society and the environment during a time of rapid environmental degradation and climate change– hinting its potential role to sustainability and socio-ecological transformation. There is virtually no study drawing the explicit interlinkages of classic psychedelic research to sustainability science but it is observed that the
