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Objectives: To examine the joint effects and mediating role of cardiovascular health (CVH) in the association between social determinants of health and mortality among postmenopausal women. Study design: A nationally representative cohort of 7577 postmenopausal women from NHANES 2003–2018, with mortality follow-up through 2019. Main outcome measures: Social determinants of health were derived from

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Background: Throughout the world many people have both obesity and chronic pain, comorbidities that decrease Health-Related Quality of Life (HRQoL). It is uncertain whether patients with comorbid obesity can maintain improved HRQoL after Interdisciplinary Multimodal Pain Rehabilitation (IMMPR). Methods: Data from 2016, 2017, and 2018 were obtained from a national pain database for Swedish speciali

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Heritage buildings are usually culturally protected as well as naturally ventilated. As such, it is difficult to control the airflow, which depends on the temperature outdoors as well as the wind. This causes issues with the thermal comfort and the indoor air quality. In this study, status determinations were conducted for 12 heritage buildings with offices, across Sweden. Field measurements on te

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We present a fully automated generative method for simultaneous brain tumor and organs-at-risk segmentation in multi-modal magnetic resonance images. The method combines an existing whole-brain segmentation technique with a spatial tumor prior, which uses convolutional restricted Boltzmann machines to model tumor shape. The method is not tuned to any specific imaging protocol and can simultaneousl

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Background: Every year, many infants are infected with the respiratory syncytial virus (RSV) or other agents and need hospitalisation due to bronchiolitis. The disease causes much suffering and high costs. Thus, it is important that the treatment methods are both effective and cost-efficient. The use of different physiotherapy treatment methods is debated, and not all methods are evaluated scienti

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Alfa Laval är marknadsledande på teknologin packningsförsedda plattvärmeväxlare (GPHE). För att behålla sin position som marknadsledare inom GPHE-sektorn så utför Alfa Laval regelbundet designstudier. Designstudierna utförs för att undersöka nya lösningar och få inspiration till nya möjliga funktioner. Alfa Laval strävar alltid efter att förbättra sina produkter med avseende på många faktorer, exeAlfa Laval is the market leader within gasketed plate heat exchanger (GPHE) technology. To remain the leader of the GPHE sector, Alfa Laval regularly performs design studies to investigate new solutions and find inspiration for possible functions. Alfa Laval always work to improve their products, regarding many aspects, such as manufacturability, distribution, and maintenance as well as sustainabi

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The aim of this study was to investigate how social workers reflect on municipal activation for clients who receive financial assistance, and the boundaries the social workers set in regard to the Swedish Public Employment Service. The aim is also to analyze which activation measures are used in the municipality, why they are used and how the social workers use their discretion in decision-making.

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In the field of molecular biology, the cloning of DNA is a vital process. Through cloning, researchers can design new DNA strands which can be used for a number of applications. One of these applications is the creation of synthetic antibodies for cancer treatments. Alligator Bioscience is developing a high-throughput chain to significantly speed up the process. Traditional cloning techniques rely

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The development research has stressed the importance of technical and vocational education and training for systemic progress in a society. However, proscribed donor-centred solutions often fail to deliver the expected result. As such enabling the local stakeholders and supporting their ideas rather than enforcing the donors' own visions is seen as a promising way to engage in development poli

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Background: Premature ventricular complexes (PVCs) predict coronary heart disease, heart failure, atrial fibrillation and death, all of which are also related to sodium intake. We studied estimated sodium intake and PVC frequency in the randomly selected population-based Swedish CArdioPulmonary bioImage Study cohort. Methods: In our cross-sectional study, we included 5636 individuals with 24-hour

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Chronic breathlessness is a common and distressing symptom, negatively impacting physical function and quality of life. Many individuals presenting with chronic breathlessness wait years for an explanatory diagnosis, leading to delays in accessing effective treatments and worse individual outcomes including premature mortality. In addition, delays to diagnosis are associated with increased healthc

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Background: Gaming disorder has recently been recognized as a psychiatric condition, yet the clinical characteristics of treatment-seeking individuals remain understudied. This study examined youth and adults seeking treatment at a specialized outpatient clinic in southern Sweden.Methods: A total of 107 individuals aged 12-49 years (M = 22.1, SD = 7.2) underwent comprehensive clinical interviews,

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Background: Surgery is the curative therapy for patients with medullary thyroid carcinoma (MTC). In determining the extent of surgery, the risk of complications should be considered. The aim of this study was to assess procedure-specific outcomes and risk factors for complications after surgery for MTC. Methods: Patients who underwent thyroid surgery for MTC were identified in two European prospec

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Infantile malignant osteopetrosis is a devastating disorder of early childhood that is frequently fatal and for which there are only limited therapeutic options. Gene therapy utilizing autologous hematopoietic stem and progenitor cells represents a potentially advantageous therapeutic alternative for this multisystemic disease. Gene therapy can be performed relatively rapidly following diagnosis,

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Background: In adults and adolescents with asthma, use of ≥3 short-acting β2-agonist (SABA) canisters/year is associated with increased exacerbation risk. Whether this association is present in younger children remains unknown. In this SABA use IN Asthma (SABINA) Junior study, we assessed the association of SABA collection with exacerbation risk in the general Swedish pediatric asthma population.

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Objective High vitreous levels of soluble (s)CD163 have been demonstrated in severe diabetic retinopathy (DR). The aim of this study was to explore the predictive values of plasma sCD163 and glycated haemoglobin (HbA1c) for DR progression in adults with type 1 diabetes. Methods and analyses The study design was prospective. Fundus photography performed in 2009 and at follow-up (≤12 years later) we

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Performance-based, service-life design of wood has been the focus of much research in recent decades. Previous works have been synthesized in various factorized design frameworks presented in the form of technical reports. Factorization does not consider the non-linear dependency between decay-influencing effects, such as between detail design and climate variables. The CLICKdesign project is a jo

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Purpose:The article makes an empirical and conceptual contribution to understanding the temporalities of information literacies. The paper aims to identify different ways in which anticipation of certain outcomes shapes strategies and tactics for engagement with algorithmic information intermediaries. The paper suggeststhat, given the dominance of predictive algorithms in society, information lite