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Worse self-reported outcomes but no limitations in performance-based measures in patients with long-standing hip and groin pain compared with healthy controls

PURPOSE: This study aimed to evaluate patient-reported outcomes as well as lower extremity and trunk muscle function in patients with long-standing hip and groin pain, in comparison with matched, healthy controls. It was hypothesized that patients with long-standing hip and groin pain would report more deficiency on the Copenhagen Hip and Groin Outcome Score (HAGOS) and have worse outcomes on perf

Changes in joint cartilage aggrecan after knee injury and in osteoarthritis

Objective. To determine the concentrations of aggrecan fragments in synovial fluid from patients with knee joint injury, osteoarthritis (OA), or acute pyrophosphate arthritis (PPA; pseudogout), and to test their relative reactivity with the 846 epitope, a putative marker of cartilage aggrecan synthesis. Methods. Samples of knee joint fluid from 385 patients and 9 healthy-knee volunteers were obtai

Managing human fear of bears and wolves

Decision-makers and managers spend substantial amounts of funding everyday on various interventions aimed at management of the large carnivores, for example different measures to mitigate depredation on livestock, e.g., removal of carnivores and fencing of livestock (see Linnell et al. 1996 for an extensive review). Management of species that occur in low numbers is challenging as relatively small

Wavelet decomposition for detection of chaotic characteristics of monthly precipitation at Mokpo, Korea

In the present study, we apply deterministic chaos theory to investigate nonlinear dynamics in monthly precipitation at Mokpo, Korea, after wavelet decomposition. The wavelet transform is used not only for removal of noise but also for extraction of low and high frequency components in the data, representing low-dimensional dynamics. In order to determine an appropriate decomposition level for the

Prevalence and comorbidity in a Swedish adolescent community sample – gambling, gaming, substance use, and other psychiatric disorders

Background: This study investigates a broad spectrum of psychiatric disorders, substance use disorders, gambling, and internet gaming disorders in Swedish 18-year-old boys and girls with the aim of estimating the prevalence of disorders and comorbidity. Methods: We used a two-phase design with screening to detect candidates for clinical interviews. Screening included 949 adolescents (55.6% girls),

Effectiveness of first generation disease-modifying therapy to prevent conversion to secondary progressive multiple sclerosis

Background: The use of disease-modifying therapies (DMTs) in multiple sclerosis (MS) has been associated with reduced relapse rates and accumulation of disability. However, studies examining impact of DMT on risk of transition to secondary progressive MS (SPMS) leveraging population-based nationwide data are still rare. Here, we determine the population incidence of conversion to SPMS using two co

A co-created nurse-driven catheterisation protocol can reduce bladder distension in acute hip fracture patients - results from a longitudinal observational study

Background: Urinary retention is common in elderly patients undergoing acute hip fracture surgery. Avoiding overfilling the urinary bladder is important to avoid detrusor muscle damage and associated motility problems. The aim of this study was to analyse associations between the co-creation of a nurse-driven urinary catheterisation protocol and the incidence of bladder distension in patients unde

Knowledge of Human Monkeypox and Its Relation to Conspiracy Beliefs among Students in Jordanian Health Schools : Filling the Knowledge Gap on Emerging Zoonotic Viruses

Background and Objective: The recent multi-country outbreak of human monkeypox (HMPX) in non-endemic regions poses an emerging public health concern. University students in health schools/faculties represent a core knowledgeable group that can be helpful to study from a public health point of view. As future healthcare workers, assessment of their knowledge and attitude towards emerging zoonotic v

Estimation of actual evapotranspiration : A novel hybrid method based on remote sensing and artificial intelligence

Actual evapotranspiration (AET) is one of the decisive factors controlling the water balance at the catchment level, particularly in arid and semi-arid regions, but measured data for which are generally unavailable. In this study, performance of a base artificial intelligence (AI) model, adaptive neuro-fuzzy inference system (ANFIS), and its hybrids with two bio-inspired optimization algorithms, n

Prevalence of and factors associated with early initiation of breastfeeding among women with children aged < 24 months in Kilimanjaro region, northern Tanzania : A community-based cross-sectional study

Background: Early initiation of breastfeeding offers nutritional and immunological benefits to the newborn, which is critical for health and survival. Understanding factors associated with timely initiation of breastfeeding is crucial for healthcare providers and policy-makers. This study aimed to assess the prevalence and factors associated with early initiation of breastfeeding among mothers wit

DynSus : Dynamic sustainability assessment in groundwater remediation practice

Decision-making processes for clean-up of contaminated sites are often highly complex and inherently uncertain. It depends not only on hydrological and biogeochemical site variability, but also on the associated health, environmental, economic, and social impacts of taking, or not taking, action. These variabilities suggest that a dynamic framework is required for promoting sustainable remediation

Galectin-4 levels in hospitalized versus non-hospitalized subjects with obesity : the Malmö Preventive Project

BACKGROUND: Obesity is strongly associated with the development of cardiovascular disease (CVD). However, the heterogenous nature of obesity in CVD-risk is still poorly understood. We aimed to explore novel CVD biomarkers and their possible association with presumed unhealthy obesity, defined as hospitalized subjects with obesity (HO).METHODS: Ninety-two proteins associated with CVD were analyzed

A Clash of Ideals : The Introduction of Televised Information in Sweden, 1969–1972

In 1969, a government report concluded that there was a need for closer contact between the citizens and Swedish government agencies. Television, at this time still considered a new medium, was highlighted in the report as a valuable form of mass communication with great yet unfulfilled promise as a disseminator of government information. A heated debate about the role and function of government i

REM-Predominant Obstructive Sleep Apnea in Patients with Coronary Artery Disease

Obstructive sleep apnea (OSA) is common in adults with coronary artery disease (CAD). OSA that occurs predominantly during rapid-eye movement (REM) sleep has been identified as a specific phenotype (REM-predominant OSA) in sleep clinic cohorts. We aimed to examine the association of REM-predominant OSA with excessive sleepiness, functional outcomes, mood, and quality of life in a CAD cohort, of wh

Predictors of ASDAS-CRP inactive disease in axial spondyloarthritis during treatment with TNF-inhibitors : Data from the EuroSpA collaboration

Objectives: In patients with axial spondyloarthritis (axSpA) initiating their first tumor necrosis factor alpha-inhibitor (TNFi), we aimed to identify common baseline predictors of Ankylosing Spondylitis Disease Activity Score (ASDAS-CRP) inactive disease (primary objective) and clinically important improvement (CII) at 6 months, and drug retention at 12-months across 15 European registries. Metho

The natural menstrual cycle revisited – can natural cycle be trusted

Background: The serum progesterone (P4) level during the luteal phase (LP) plays a crucial role in the initiation and maintenance of pregnancy. However, it is unclear whether the natural cycle consistently provides the best endocrine profile and whether mid-luteal serum P4 levels are always sufficient to support implantation and early pregnancy. The question has become more relevant in relation to

Association of MAFLD and MASLD with all-cause and cause-specific dementia : a prospective cohort study

Background: Liver disease and dementia are both highly prevalent and share common pathological mechanisms. We aimed to investigate the associations between metabolic dysfunction-associated fatty liver disease (MAFLD), metabolic dysfunction-associated steatotic liver disease (MASLD) and the risk of all-cause and cause-specific dementia. Methods: We conducted a prospective study with 403,506 partici