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Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou
Pyranose 2-oxidase (P20x) has several proposed biotechnological applications such as a bio-component in biofuel cells or for carbohydrate transformations. To improve some of the catalytic properties of P20x from Trametes multicolor, we selected a semi-rational approach of enzyme engineering, saturation mutagenesis of active-site residues and subsequent screening of mutant libraries for improved ac
The role of cholesterol differs in the two compartments of the testis. In the interstitial tissue, cholesterol is necessary for the synthesis of testosterone, whereas in the seminiferous tubules, membrane cholesterol content in developing germ cells will influence the gametes' fertility. Here we evaluate the hormone-sensitive lipase (HSL) modulation of the cholesterol metabolism in each compartmen
Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.
Humanistiska och teologiska fakulteterna bedriver en bred och varierad verksamhet inom forskning och utbildning som i vid mening syftar till att förstå människan som kulturell och samhällelig varelse. Vi forskar och utbildar inom områden som behandlar kulturmöten, språk, historia, etik, religion, filosofi, konst, musik, litteratur och annat som formar och definierar kulturerna.The Joint Faculties of Humanities and Theology provide research and education in a broad range of subjects, ranging from cultural sciences, history, philosophy, archaeology, languages and literature to theology and religious studies.
Relocation to residential care facilities is a unique type of transition. For most older people it is the lastmove they make in their life when they have no other options. The transition itself involves numerouschallenges. There is a lot of knowledge about the situations before and after relocating to a nursing home,but few studies are based on the actual relocation process. This paper explores olRelocation to residential care facilities is a unique type of transition. For most older people it is the lastmove they make in their life when they have no other options. The transition itself involves numerouschallenges. There is a lot of knowledge about the situations before and after relocating to a nursing home,but few studies are based on the actual relocation process. This paper explores ol
FVP 2026.indd Verksamhetsplan 2026 GEMENSAMMA FÖRVALTNINGEN | LUNDS UNIVERSITET GEMENSAMMA FÖRVALTNINGENS VERKSAMHETSPLAN 2026 © Lunds universitet 2026 www.lu.se lu@lu.se TRYCK Media-Tryck, LU Service, Lunds universitet www.mediatryck.lu.se media-tryck@service.lu.se Svanenmärkt trycksak, 341903 PROJEKTLEDARE Susanne Hägerström, Utveckling FORMGIVNING Stefan Andersson, LU Service TEXTBEARBETNING Su
BACKGROUND: Definition of temporal serum proteome profiles after out-of-hospital cardiac arrest may identify biological processes associated with severe hypoxia-ischaemia and reperfusion. It may further explore intervention effects for new mechanistic insights, identify candidate prognostic protein biomarkers and potential therapeutic targets. This pilot study aimed to investigate serum proteome p
Sektionen HR har tagit fram ett universitetsgemensamt stöd i form av en årscykel för bisyssla. Genväg:Ta del av årshjulets olika steg i löptext Årscykelns olika stegJanuariUppstart årlig anmälningsskyldighet för lärare – under första kvartalet.Information till prefekter och lärare om att bisyssla ska anmälas senast 31 mars. Hantering av anmälningar och eventuella beslut om upphörande av bisyssla.F
https://www.hr-webben.lu.se/arscykel-bisyssla - 2026-05-17
The aim of this paper is to address the importance of communication theory for the understanding of strategic communication. Underlying this focus are the debates and discussions on the definition of strategic communication, which have primarily been occupied with the meaning of the concept strategic. The definition and meaning of communication tend to be implicit or undefined and Van Ruler (2018)
The present article describes data from pilot studies with the Swedish versions of the Mindful Attention Awareness Scale (MAAS) and the Kentucky Inventory of Mindfulness Skills (KIMS). The MAAS and two of the KIMS scales, Act with Awareness and Accept without Judgment, were found to correlate in the predicted direction with measures of well-being and emotional distress. The KIMS scales Observe and
Presented here is an engineered protein domain, based on Protein A, that displays a calcium-dependent binding to antibodies. This protein, ZCa, is shown to efficiently function as an affinity ligand for mild purification of antibodies through elution with ethylenediaminetetraacetic acid. Antibodies are commonly used tools in the area of biological sciences and as therapeutics, and the most commonl
