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Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. E140Q-Tr2C exhibits global conformational exchange on the microsecond time-scale. The populati
Popular Abstract in Swedish Den moderna epokens början återfinns i det sena sjuttonhundratalet och i Europa. Det är en epok, en kultur som förstår sig som både ny och som annorlunda i förhållande till tidigare epoker och kulturer, sådana som vilat på myter, religion och tradition. Den nya kulturens fundamentala insikt bestod i att ingenting måste vara så som det är, utan allt vore möjligt också påThe problem which the present study discusses is modernity. The study interprets modernity’s cultural and anthropological dispositions as historical appearances. Consequently, it is situated at the intersection of cultural sociology and historical anthropology. The aim is to generate insight and understanding rather than a coherent theory. The key element consists of combination and variation of c
The isolation of male and female DNA is an important step in the analysis of sexual assault evidence. A vaginal swab with female epithelial cells and male sperm cells is obtained from the female, and it is vital to separate the male and female fractions in order to obtain a single-source DNA profile of the suspect. In the case of a low abundance of sperm cells, it is very important that no cells a
Popular Abstract in Swedish Denna avhandling behandlar två ämnen inom trådlös kommunikation: interferens mellan frekvenshoppande (FH) nätverk och fleranvändardiversitet. I arbetet på FH nätverk undersöks ett system där frekvenshopp används för att möjliggöra samtidig tillgång till kanalen för multipla okoordinerade nätverk. Detta åstadkoms genom att frekvenshoppen sker varje gång ett ny paket skaThis thesis deals with two topics in wireless communications: interference between frequency-hopping (FH) networks, and multiuser diversity. The work on FH treats a system where FH is used to provide simultaneous access to the channel for multiple uncoordinated wireless networks. This is achieved by performing frequency hops on a packet-by-packet basis, and letting the sequence of hopping frequen
Popular Abstract in Swedish Aktie- och fondsparandet bland allmänheten har ökat dramatiskt i Sverige under 1990-talet, och allt fler företag har valt börsintroducering som finansieringsform. På så sätt har frågor som rör värdepappersmarknaden fått en ökad och mer allmän relevans, inte minst när det gäller regleringen av vad som är tillåtet och otillåtet att göra på marknaden. Både från statligt håIn this dissertation the Swedish Financial Supervisory Authority's (FSA) investigation of suspected insider trading offences is examined and analysed. The aim of the study is to describe FSA's investigative activity in insider cases during the 1990?s, a period of both increased activity on the Swedish stock market as well as changed regulation. The study places the investigation of insider offence
Close international collaboration between pediatric oncologists has led to marked improvements in the cure of patients, seen as a long-term overall survival rate of about 80%. Despite this progress, neuroblastoma remains a challenging disease for both clinicians and researchers. Major clinical problems include lack of acceptable cure rates in high-risk neuroblastoma and potential overtreatment of
Popular Abstract in Swedish Pappersbrott i planet har studerats med hjälp av den kohesiva sprick modellen ur ett experimentellt såväl som ur ett teoretiskt perspektiv. Brott i en pappersremsa erhålls när remsan i en provmaskin belastas till sin maximala bärlast. Om remsan är tillräckligt kort fås en stabil nedåtgående last-förlängnigs kurva efter det att max lasten är nådd. Det visade sig att denThe in-plane failure of paper is studied in this work by means of a cohesive crack model from experimental as well as theoretical perspectives. Localized damage at in-plane tension of short paper strips is studied for low strain rates. It is observed that under uniaxial in-plane tensile tests, the evolution of the failure is stable and the damage of the paper strip is localized into a narrow zone
It is well-known that the participation in a design process can be experienced as being so meaningful that the participation in itself overshadows even the result of that process. The participants in this design project represent a user group that often use products in which functional value is pre-eminent: people with disabilities. Thereby special attention has been given to the concepts of stigm
Background The 2002 EU directive on the energy performance of buildings stipulates that buildings must be energy certified. In order to implement the directive in Sweden it is proposed that a law on the energy certification of buildings be introduced on 1 January 2006. The law shall apply to all buildings where energy is used to condition the indoor climate. However, there are a number of exceptio
Title: Core values and brand promises – A mixed quantitative and qualitative study of core values, brand promises and their interdependence among 104 Fortune 500 companies. Date of the seminar: May 31, 2011 Course: BUSM08 Degree Project in International Marketing and Brand Management Authors: Per Andersson and Ola Johansson Supervisor: Associate Professor Mats Urde, PhD; Docent Keywords: Core valu
Most stomatopod crustaceans have complex retinas in their compound eyes, with up to 16 spectral types of photoreceptors, but members of the superfamily Squilloidea have much simpler retinas, thought to contain a single photoreceptor spectral class. In the Atlantic stomatopod Squilla empusa, microspectrophotometry shows that all photoreceptors absorb light maximally at 517 nm, indicating that a sin
Popular Abstract in Swedish Lödda kompakta plattvärmeväxlare används i stor utsträckning i kyl – och värmepumpanläggningar samt luftkonditioneringsanläggningar. Såväl enfasvärmeutbyte, dvs värmeutbyte mellan två vätskor, som fasomvandling genom kondensation och förångning är viktiga tillämpningsområden. Apparaterna användes inom industri, hushåll, samhälleliga inrättningar mm. Prestandan för olikaThis thesis work presents various performance estimation methods of compact brazed plate heat exchangers (BPHE) operating in single phase, condenser, evaporator, cascaded and transcritical applications. Such methods play a vital role in development of heat exchanger selection software and during geometry parameter estimation in the new product development process. The suitability of employing comm
Title: How can everybody learn to sing? A study about methods for meeting students with poor singing ability I have based my work upon the question if everyone can learn how to sing. This study investigates the physical and psychological impacts that singing may have upon us and examines methods that can be used intuition. Concepts such as tone-deaf, amusia, poor pitch singing and monotones are d
This Master's thesis concerns the public library as a public meeting place. Our aim has been to find out why and how the library as a social meeting place has been discussed within the Swedish library community and if there has been a constant core in the discussions from the mid 70's and up to the present day. In order to do this we apply a place and space-perspective. The result of the s
This article examines the diffusion of meritocratic practices as a potential instance of policy transfer by scrutinizing the introduction of open and competitive examinations during the mid-nineteenth century in the British Civil Service. Scholars have argued that British reformers were inspired by meritocratic practices in British-ruled India. In order to assess this claim, we combine qualitative
Recent research has revealed that interdisciplinary work combining archaeological and heritage practice continues to be limited by enduring assumptions separating the two fields. Traditional structures and institutional barriers make it difficult to break away from what is expected in order to explore what is possible in what archaeologists and heritage practitioners ‘do’. Though archaeologists pl
Why should we teach tourism at universities?This presentation targets the question of why tourism should be part of university education. Presently, this is questioned by colleagues in traditional academic disciplines as well as by parts of the tourism industry, which are somewhat reluctant to employ people with a university degree. It is thus time for this matter to be raised. If we are to answer
GeoBIM, the integration of 3D geoinformation (Geo) with building information models (BIM), is a subject of increasing attention in both domains. A well-known practical challenge for this integration is the mixed state of software support for open standards in each domain that would ease the integration. This is often known by practitioners but poorly documented. In order to solve this problem, we
