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Inter- and intralocus recombination drive MHC class IIB gene diversification in a teleost, the three-spined stickleback Gasterosteus aculeatus

The mutational mechanism underlying the striking diversity in MHC (major histocompatibility complex) genes in vertebrates is still controversial. In order to evaluate the role of inter- and intragenic recombination in MHC gene diversification, we examined patterns of nucleotide polymorphism across an exon/intron boundary in a sample of 31 MHC class IIB sequences of three-spined stickleback (Gaster

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Valleys of Hope and Despair; peace building through independent environmental documentaries

Social and environmental documentaries aim to stress the importance of sustainable development and the need for humanity to take care of our shared planetary ecosystem. Using film as an art form to express ecological peace as a “dreamed-of order” is a way to create understanding between warring parties. Social documentaries are aimed to enlighten and inform on the positive nexus between sustainabl

A Mathematical Model for Interpretable Clinical Decision Support with Applications in Gynecology

Background: Over time, methods for the development of clinical decision support (CDS) systems have evolved from interpretable and easy-to-use scoring systems to very complex and non-interpretable mathematical models. In order to accomplish effective decision support, CDS systems should provide information on how the model arrives at a certain decision. To address the issue of incompatibility betwe

REX: A Computer Program for PIXE Spectrum Resolution of Aerosols

REX is a Fortran program for analysis of spectra obtained in PIXE analysis. The underlying model is still under development; however, one year of experience has demonstrated REX’s capability to be a fast reliable tool. The modeling of the different components and effects of the physical model is briefly discussed. Evidence is shown that secondary effects mostly due to Compton-scattering in and aro

Levodopa--carbidopa intestinal gel for treatment of advanced Parkinson''s disease

Levodopa is the mainstay of Parkinson''s disease (PD) treatment, but is often eventually associated with disabling motor complications in patients with advanced PD. The inability of perorally administered levodopa to provide more physiologic continuous dopaminergic stimulation (CDS) is a leading hypothesis to explain these complications. To investigate the cumulative efficacy and safety, and re-ev

Med främmande bagage : Tankar och erfarenheter hos unga människor med ursprung i en annan kultur eller Det postmoderna främlingskapet

Popular Abstract in Swedish Allt fler ungdomar i vårt land, liksom i många andra länder, lever i vardagen med mer än en kultur. En femtedel av eleverna i den svenska skolan är antingen själva födda i ett annat land eller har minst en förälder med utländsk bakgrund. För många av dessa barn och ungdomar har därför inte samhällets dominerande kultur funnits med från början av deras liv. Bekantskapen The present study is based on interviews with 22 youth and young adults. The perspective is phenomenological, since my aim has been to analyse and describe the everyday world as it presents itself to these young people. A process begins in the encounter with the majority culture and the emphasis is on how they think about events and experiences along the road to a more complex life-world. The proc

Från patient till kund : Intåget av marknadstänkande i sjukvården och förskjutningen av patientens position

Popular Abstract in Swedish Avhandlingens forskningsfrågor är: ”Vad är det som har möjliggjort att det talas om sjuka som kunder, hur har en sådan förskjutning av föreställningen om den sjuke skett och vad medför en sådan förskjutning?” Marknadstänkandet har successivt introducerats inom sjukvården under de sista decennierna av 1900-talet. Marknadstänkandet försöker ersätta tidigare förvaltnings-Marketization of society has gradually transformed health care at the end of the 20th century. The conditions of possibility for this transformation have been the social impact of the market discourse and the discourse on patient rights. These discourses brought about a displacement of the discursive order in health care. One effect of this discursive break was that the view of the sick person was

Improving minimum flow rate in wireless mesh networks by effective placement of directional antennas

For some time, directional antennas have been considered to solve connectivity and interference issues in wireless networks. Several scenarios have been presented and often the conclusions drawn are positive, showing increase in capacity. However, to date there has been no effort to assess a holistic picture of the benefit/cost tradeoff and previous work mainly concerns either link scheduling or a

Assessing ‘Green Energy Economy’ policies for transforming the building stock in Shanghai

The 2008–2009 global financial crisis triggered ‘Green Energy Economy’ (GEE) policy packages to stimulate green growth in many countries. China soon became a leader and, supported by its 11th Five-Year Plan (2006–2010), devoted approximately one-third of its US$ 647 billion stimulus package to green energy technologies. Since then, numerous policy instruments have been implemented to encourage ‘Gr

Ethanol from Sugarcane Lignocellulosic Residues - Opportunities for Process Improvement and Production Cost Reduction

Popular Abstract in English Modern society is still largely based on fossil resources. However, there are growing concerns about the security and cost of these resources, as well as climate change resulting from the combustion of fossil fuels. Biofuels represent renewable fuels with the potential to mitigate the adverse effects of fossil fuels, providing a more sustainable alternative. The transpBioethanol from sugarcane is a sustainable alternative to fossil fuels, and the increasing demand for fuel ethanol has prompted studies on the use of the lignocellulosic residues of sugarcane, namely bagasse and leaves, as new feedstock. This thesis describes various process designs and the economic feasibility of producing second generation (2G) ethanol from bagasse and leaves via the enzymatic r

Staging Science : Some aspects of the production and distribution of science knowledge

Popular AbstractAvhandlingen presenterar, från ett fenomenologiskt perspektiv, interaktionen mellan naturvetenskapens kunskap och annan kunskap, här kallad "vardagskunskap". Utgångspunkten i presentationen är människans existens. Två aspekter av denna lyfts fram som centrala - att människan är kroppsligt utsatt för, berörd av, något hon inte har full kontroll över, samt att hon alltid agerar utifrThe dissertation presents a phenomenological view on the interaction between science knowledge and prescientific knowledge. Drawing on Husserl, Merleau-Ponty and Lévinas the human bodily grounded existence is described, the central feature of this existence being its responsivity to the Other. This responsivity is presented as the starting point for the production of science knowledge, thus making

Determination of atmospheric trace gas amounts and corresponding natural isotopic ratios by means of ground-based FTIR spectroscopy in the high Arctic

Abstract In the given report, scientific results gathered at the Alfred- Wegener- Institut für Polar- und Meeresforschung (AWI) within an ScD contract are summarized. The AWI is the German large scale research facility for polar- and marine research. In January 1992 +he new research de- partment at Potsdam has been established with the section Physics und Chemistry of the Atmosphere. 1t coordinate

Photography and temperature measurements from a remotely piloted vehicle

Radio-controlled model planes are useful when carrying out photography, especially from low altitudes, and meteorological soundings (air temperatures in boundary layers). Soundings were carried out with a system which stored the measured data on board the plane pending evaluation after the flight. The payload of the plane was a camera and equipment for measuring temperature and air pressure (altit

Wireless Esophageal pH Monitoring Is Better Tolerated than the Catheter-Based Technique: Results from a Randomized Cross-Over Trial.

OBJECTIVES: Esophageal pH monitoring using a wireless pH capsule has been suggested to generate less adverse symptoms resulting in improved patient acceptance compared with the catheter-based method although evidence to support this assumption is lacking. The aim of this study was to evaluate and compare the subjective experience of patients undergoing both techniques for esophageal pH monitoring.

Modern Thermal Power Plants - Aspects on Modelling and Evaluation

The European Union (EU) has laid down very clear objectives for the reduction of greenhouse gases in the hope that it will prevent or mitigate climate change. Political incentives are used to make the power industry adopt changes in order to reach these EU targets. In this thesis, some solutions that could help power companies meet the EU objectives are evaluated. Thermodynamic models have been de

Joint owned companies as instrument of Local Government: Comparative evidence from the Swedish and Italian water sector

The combination of features from the public and private sectors in jointly owned companies imposes challenges to the governance and control mechanisms of these organisations, which have been criticised for lacking accountability. Where there is fragmented ownership, the interests of different owners need to be coordinated. The aim of this article is to consider how such companies can be governed i

MRI Characteristics of Pediatric Renal Tumors : A SIOP-RTSG Radiology Panel Delphi Study

Background: The SIOP-Renal Tumor Study Group (RTSG) does not advocate invasive procedures to determine histology before the start of therapy. This may induce misdiagnosis-based treatment initiation, but only for a relatively small percentage of approximately 10% of non-Wilms tumors (non-WTs). MRI could be useful for reducing misdiagnosis, but there is no global consensus on differentiating charact