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Previous studies have suggested that the development of diabetes in the BB rats does not require the expression of T lymphopenia. In order to derive non-lymphopenic diabetic rats and define the relationship between the T cell abnormalities, MHC genotype, and diabetes, we performed a cross between BB/H and diabetes resistant BB/control followed by an intercross of the F1. In the F2, the overall inc
Background: Intra- and interfractional variations in anatomy can cause unplanned substantial alterations of the dose distribution of the target in proton therapy. Motion management methods might be used in order to minimize anatomical variations. In the proton therapy of lung cancer, a potential motion management technique is the use of the voluntary breath-hold approach. The aim of this study was
Field trials in three European countries, the Netherlands, Spain and Sweden were carried out in order to investigate the effects of an in-car speed limiter. The trials were carried out on urban and rural roads including motorways. A so-called unobtrusive instrumented car was used, where all the measuring equipment was hidden. All the speed limit categories in the respective countries, ranging from
The transglycosylation behavior and capacity of two clan GH-D α-galactosidases, BoGal36A from the gut bacterium Bacteroides ovatus and Aga27A from the guar plant, was investigated and compared. The enzymes were screened for the ability to use para-nitrophenyl-α-galactoside (pNP-Gal), raffinose and locust bean gum (LBG) galactomannan as glycosyl donors with the glycosyl acceptors methanol, propanol
Trichoderma atroviride mutants were developed by using N-methyl-N'-nitro-N-nitrosoguanidine (NTG) treatment and UV-Iight followed by a semiquantitative plate clearing assay on Walseth-cellulose/agar plates. The parent strain of the mutants was an isolate from the Amazonas basin (TUB F-1505), whose identity was established by ITS 1 and 2 and tef1 gene sequence analysis. Strain F-1505 proved to be t
A simple, rapid and environmentally friendly hollow-fibre liquid-phase microextraction (HF-LPME) technique was developed for the quantitative determination of polycyclic aromatic hydrocarbons (PAHs) in aqueous samples. GC-MS was then used as the method of analysis. The HF-LPME technique involves extraction of PAHs from a 20-mL sample containing 20 % acetonitrile as a modifier. The PAHs were extrac
Life oil earth was formed during billions of years, exposed to, and shaped by the original physical forces such as gravitation, cosmic irradiation, atmospheric electric fields and the terrestrial magnetism. The Schumann resonances at 7.4 Hz are all example of oscillations possibly important for life.(1)) The existing organisms are created to function in harmony with these forces. However, in the l
The calculation of absorbed dose from internally incorporated radionuclides is based on the so-called specific absorbed fractions (SAFs) which represent the fraction of energy emitted in a given source region that is absorbed per unit mass in a specific target organ. Until recently, photon SAFs were calculated using MIRD-type mathematical phantoms. For electrons, the energy released was assumed to
The overall aim of this thesis was to investigate the initial diabetes education process, the impact on children and their parents and parental satisfaction with the care received one and two years subsequent to the child’s diagnosis. In order to seek a deeper understanding for how the diabetes team’s initial education process works from admission to discharge among families with a child newly dia
In this study, characterization of the binding kinetics and optimization of a magnetic permeability based point-of-care (POC) immunoassay system for quantification of canine C-reactive protein (cCRP) is described. The reagent is based on a two-site heterogeneous immunoassay system utilizing conjugated superparamagnetic nanoparticles (SPION) and silica particles, both particles carrying covalently
In order to simplify computational methods based on dynamic programming, a relaxed procedure based on upper and lower bounds of the optimal cost was recently introduced. The convergence properties of this procedure are analysed here. In particular, it is shown that the computational effort in finding an approximately optimal control law by relaxed value iteration is related to the polynomial degre
We image the field enhancement at Ag nanostructures using femtosecond laser pulses with a center wavelength of 1.55 mu m. Imaging is based on non-linear photoemission observed in a photoemission electron microscope (PEEM). The images are directly compared to ultra violet PEEM and scanning electron microscopy (SEM) imaging of the same structures. Further, we have carried out atomic scale scanning t
Popular Abstract in Swedish ”Vi kommo överens om att möten innehålla alla livets möjligheter, och att en människa som levat mycket vet mycket om möten om hon alls vet någonting.” Så uttalar den kvinnliga huvudpersonen i Mannen vid min sida (1933) sin övertygelse efter mötet med älskaren. Denna avhandling fokuserar mötet i Elin Wägners trettiotalsromaner. Genom att analysera detta vill avhandlingsfThe aim of this present thesis is to present the Utopian scheme in Elin Wägner’s novels of the nineteen-thirties: Dialogen fortsätter (1932) (“The Dialogue Continues”), Mannen vid min sida (1933) (“The Man by my Side”), Genomskådad (1937) (“Unmasked”) and Hemlighetsfull (1938) (“Mysterious”). With her authorship Wägner was aiming for a new social order, a radical change, polväxling (a shift of pol
In order to identify the importance of different areas for nitrogen retention in the Lagoon of Venice, Italy, undisturbed sediment cores of different origin were collected in late April 1998. The cores were transferred to the laboratory and incubated for denitrification activity using the method of 'nitrogen isotope pairing'. The sampled sediments were collected in a freshwater stream (Stn A)I an
The increasingly frequent use of forensic evidence in the prosecution of criminal cases should in the long run result in increased analysis of its effectiveness. To date, such analysis has been limited, most probably due to rights of parties to use forensic evidence to support their respective arguments in cases and the rights of the courts to assess and rely on such evidence in criminal cases. Pr
This master thesis contains an overview of existing additive manufacturing methods and considers possible new methods. The purpose being to develop a method for additive manufacturing that can create 3D objects with composite material and/or out of metal. Further this method should work on a low cost additive manufacturing machine. A development process is used in order to select an appropriate me
För att undersöka nanopartiklars toxicitet finns behov av att producera väldefinierade nanopartiklar dispergerade i en kolloid suspension. Men även för andra områden så som nanomedicin finns ett behov av denna typ av lösningar. För att dispergera partiklarna i vätska används ofta ytaktiva ämnen. När dessa ämnen tillsätts adderas de på ytan av partikeln och förändrar partiklarnas yta. Då forskning To examine nanoparticle toxicity there is a need to produce defined nanoparticles dispersed in a colloidal suspension. Such a solution could also be interesting for other fields such as nano-medicine. In order to disperse the particles in the liquid there are often surfactant added to the process that alternates the surface of the particles. As the research shows that the surface of a nanoparticle
Background: Inflammation is an immune-mediated response by mammalian species to protect the host from infectious and non-infectious insults. An allergic airway inflammation, which is an inflammatory response to otherwise harmless allergens, underlies common diseases like asthma and allergic rhinitis (hay fever). It is estimated that 10-20 % of the world population is affected by airway inflammator
I det här examensarbetet har en ny förpackningslösning utvecklats och konstruerats för snäckfräsar till Volvo Group Truck Operation Powertrains transmissionsfabrik i Köping. Det fanns ett behov av en ny förpackningslösning då den existerande förpackningen har flertalet problem och brister och börjar bli föråldrad. Produktutvecklingen började med att bekanta sig med den nuvarande förpackningen ochIn this thesis, a new packaging solution has been developed and designed for gear hobs to Volvo Group Truck Operation Powertrain´s transmission plant in Köping. There was a need for a new packaging solution since the existing packaging have a number of problems and deficiencies and begins to be obsolete. The product development began by familiarizing with the current packaging and how it was hand
Efforts to reduce energy consumption in buildings have increased with the pending impact of climate change. Heat losses through airing behaviours remain a largely unknown factor due to the variety of reasons for opening a window, making generalization difficult. Currently, an estimation of 4 kWh/m2 heated area for airing heat loss is assumed in Sweden. Additionally, the resulting airflow from open
