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We analyzed 37 primary invasive carcinomas for BRCA1 and BRCA2 mutations by screening the entire coding regions of both genes. Seven predicted truncating mutations (four in BRCA1 and three in BRCA2) and one novel BRCA1 missense variant (S1542C) were identified (8/37, 22%). Two of the BRCA1 mutations were somatic changes, whereas the remaining three BRCA1 changes and all mutations of BRCA2 were fou
Fuerzas de Cambio II Reconociendo la Contribución de las Mujeres de América Latina y el Caribe al Desarme Forces of Change II Recognizing the Contribution of Latin American and Caribbean Women to Disarmament Avenida Pérez Araníbar 750 Magdalena del Mar Lima, Perú With the support of Con el apoyo de www.unlirec.org Tel: 51.1.625.9114 F u e r za s d e C a m b io II / F o r c e s o f C h a n g e II U
https://rwi.lu.se/app/uploads/2015/05/Forces-of-Change-II.pdf - 2026-04-24
Universitetslektor Kontaktinformation E-post: linnea [dot] wegerstad [at] jur [dot] lu [dot] se Telefon: +46 46 222 11 16Organisation Juridiska institutionen Rumsnummer: 328 Hämtställe: 56 WebbplatsLinnea Wegerstads profil i Lunds universitets forskningsportalAndra roller Forskare Rätt och utsatthet Forskare Straffrätt Forskare Health Law Docent Juridiska institutionen Publikationer Visar av publi
https://www.jur.lu.se/linnea-wegerstad - 2026-04-24
Universitetslektor Kontaktinformation E-post: magnus [dot] johansson [at] fek [dot] lu [dot] se Telefon: +46 46 222 78 41Organisation Strategi Hämtställe: 10 WebbplatsMagnus Johanssons profil i Lunds universitets forskningsportal Publikationer Visar av publikationer. Sorterade efter år och sen titel. Filtrera efter typ AllaArtikel i tidskriftDel av eller Kapitel i bokDoktorsavhandlingKonferens - a
https://www.ehl.lu.se/magnus-johansson - 2026-04-24
A Saccharomyces cerevisiae screening strain was designed by combining multiple genetic modifications known to improve xylose utilization with the primary objective of enhancing xylose growth and fermentation in xylose isomerase (XI)-expressing strains. Strain TMB 3045 was obtained by expressing the XI gene from Thermus thermophilus in a strain in which the GRE3 gene coding for aldose reductase was
Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and oxidoreductase NAD-binding domain containing 1 (OXNAD1) genes. The UV-signature mutations occurred at
Advances in next-generation RNA-sequencing have revealed the complexity of transcriptomes by allowing both coding and noncoding (nc) RNAs to be analyzed. However, limited data exist regarding the whole transcriptional landscape of chronic lymphocytic leukemia (CLL). In this pilot-study, we evaluated RNA-sequencing in CLL by comparing two subsets which carry almost identical or `` stereotyped'' B-c
Increased productivity is of societal good and efforts to achieve this should be a relevant task for all businesses. However, the concept of productivity is not clear as to what is to be measured. This becomes a problem especially when statements are made that the development of productivity in the construction industry is not as good as other sectors of industry. It is not clear if this compariso
In every gathered group of people, one person will be appointed the leadership. The choice of leader will be mutual and based on that this person has the most appropriate and trained talent for leadership and is best prepared for the task. Ultimately there should be a team of leaders that support each other and co operate in the leadership, or take turns. Leadership is dependent on the human facto
Background Gadolinium (Gd) neutron capture therapy (GdNCT) is based on a neutron capture reaction (NCR) that involves emission of both short and long range products. The aim of this study was to investigate both the microscopic and macroscopic contributions of the absorbed dose involved in GdNCT. Methods Cylindrical containers with diameters 1-30 mm filled with a solution of Gd were irradiated wit
Purpose: The aim of this study was to explore how women experienced sexuality after radical cystectomy due to bladder cancer. Methods: We performed an interview study with qualitative design with content analysis. Inclusion criteria were age below 75 years. In total 10 women, with a median age of 64 years at surgery, were interviewed at median 24 months post radical cystectomy. Results: The 10 wom
BackgroundMizoram has the highest incidence of cancer in India. Among women, breast cancer is most prevalent and the state occupies fifth position globally. The reason for high rate of cancer in this region is still not known but it may be related to ethnic/racial variations or lifestyle factors.MethodsThe present study aims to identify the candidate mitochondrial DNA (mtDNA) biomarkers—ND1and ATP
PurposeThe aim was to explore factors affecting guideline adherence among doctors in the emergency department and to explore the general perception about local guidelines for traumatic brain injuries.MethodsThirty semi-structured interviews were conducted with doctors with experience working in the emergency department regarding different aspects of guideline use, with emphasis on the management o
Purpose: To differentiate PCA segments and cortical branches by means of transcranial color-coded duplex sonography (TCCD) and to measure flow parameters at rest and during visual stimulation. Materials and Methods: 60 healthy subjects with a good acoustic temporal bone window were examined. The main stem of the PCA (P1, P2 and P3) and 4 main cortical branches-the anterior temporal artery (ATA), t
Empirical software engineering research relies on good communication with industrial partners. Conducting joint research both requires and contributes to bridging the communication gap between industry and academia (IA) in software engineering. This study aims to explore communication between the two parties in such a setting. To better understand what facilitates good IA communication and what pr
The present study aims to investigate the motives behind the culture of silence among young adults in Malmö. Based on the purpose, the study is expected to contribute with knowledge of the police's experience of silence culture among young people and how police officers handle meetings with young people in Malmö who do not want to comment in interrogation situations due to prevailing norms of
The purpose of this study was to examine how body therapy is implemented in the social work and how staff at HVB-home is motivating body therapy in addiction treatment. The study is based on qualitative interviews with staff at HVB-homes that practise body therapy. The results of the study shows that the way body therapy is implemented vary between different HVB-homes. Some combine body therapy wi
Syftet med studien var att få en fördjupad kunskap om ickebinära transpersoners vårderfarenheter och hur dessa kan förbättras. En kvalitativ metod med hermeneutisk och fenomenologisk ansats användes. Fem semistrukturerade intervjuer genomfördes med individer som identifierade sig som ickebinära transpersoner, och i analysen av materialet användes Interpretative Phenomenological Analysis (IPA). I sThe aim of the study was to explore the healthcare experiences of non-binary transgender individuals, and possible improvements of healthcare services. A qualitative method with a hermeneutic and phenomenological approach was used. Five semi structured interviews were conducted, with self-identified non-binary transgender individuals. The transcripts were analysed according to the Interpretative P
Abstract Authors: Nina Niemelä and Christian Persson Title: About the art of being a relative – a qualitative research about being the relative of a person who is abusing drugs Supervisor: Lars Harrysson This study is written as an attempt to shed light on the relatives to people who are abusing drugs or alcohol. We have aimed to explain and research how the relatives are effected by and handle t
The trope solution to the problem of mental causation combines a trope monism, i.e. that properties are tropes and all tropes are physical, with a type dualism, i.e. that although all tropes are of a physical type, there are subsets of tropes that are also of a mental type. It does so in order to reconcile three individually plausible yet seemingly incompatible principles that together would ensur
