Sökresultat

Background:To evaluate the relationships between postnatal change in circulatory insulin-like growth factor I (IGF-I) concentrations, brain volumes, and developmental outcome at 2 years of age in very preterm infants.Methods:IGF-I was measured weekly and nutritional intake was calculated daily from birth until a postmenstrual age (PMA) of 35 weeks. Individual beta coefficients for IGF-I, IGF-I(B)

Many individuals treated for depression suffer relapse or recurrence after treatment. Known risk factors include number of previous depressive episodes and residual symptoms after treatment. Both relapse/recurrence rates and predictors of relapse/recurrence, however, may differ between various settings. To perform a naturalistic evaluation of the sustained effectiveness of treatment for adult clin

BACKGROUND: Performance status (PS) is known as one of the strongest prognostic factors for survival in metastatic colorectal cancer patients. The aim of the present study was to analyze factors associated with poor PS assessed after resection for colorectal liver metastases and the impact on survival.METHODS: All patients undergoing curative resection for colorectal liver metastases between 2010

This study focuses on the development of unstructured models, including both substrate and product inhibition, that predict the cultivation of Actinobacillus succinogenes and Basfia succiniciproducens on a mixture of C5 and C6 sugars, similar to the sugar composition contained in spent sulphite liquor, the liquid waste stream from the sulphite pulping process. The main sugar monomer contained in t

Background: The Catquest-9SF questionnaire is a patient reported outcome measure that quantifies the visual benefits from cataract surgery. The purpose of this study was to translate and adapt the Catquest-9SF questionnaire for France, to assess its psychometric properties via Rasch analysis, and to assess its validity when completed using an electronic notepad. Methods: The Catquest-9SF questionn

Apolipoprotein A-I (apoA-I) is the major protein component of high density lipoproteins (HDL) and plays a central role in cholesterol metabolism. The lipid-free/lipid-poor form of apoA-I is the preferred substrate for the ATP-binding cassette transporter A1 (ABCA1). The interaction of apoA-I with ABCA1 leads to the formation of cholesterol laden high density lipoprotein (HDL) particles, a key step

Complete blood counts with red blood cell determinants associate with reduced beta‐cell function in seroconverted Swedish TEDDY children Endocrinol Diab Metab. 2021;4:e00251.  | 1 of 10 https://doi.org/10.1002/edm2.251 wileyonlinelibrary.com/journal/edm2 Received: 24 November 2020  | Revised: 1 March 2021  | Accepted: 22 March 2021 DOI: 10.1002/edm2.251 O R I G I N A L R E S E A R C H A R T I C L

https://www.teddy.lu.se/sites/teddy.lu.se/files/2022-10/133_MP239_Salami_EndoDiabMetab_2021.pdf - 2026-05-26

DIACLINCD240080_proof.pdf - 04292025_679_175_MP173_ODonnell_Clin Diabetes_2025.pdf :ghkbpdlr TlbdprsYlbhlf ne Ehri enp Suod ChYadsdr1 Sgd SDCCU Rstbu Gniiv MBnmmdii, Onv SYltpY1 KYtpY Rlhsf23 Jhladpiv Bphrbnii4 HdrrhbY Ldihm5 Jhladp Rhllnmr, Ymc RtyYmmd 7dmmdss Hnfmrnm6 enp sfd SDBBW Rstcv Epnto Sghr rstcx) oYps ne sgd nmfnhmf SDCCW Sgd Dmuhpnm, ldmsYk CdsdplhmYmsr ne ChYadsdr hm sgd Wntmf( rstcx

https://www.teddy.lu.se/sites/teddy.lu.se/files/2025-07/175_MP173_ODonnell_Clin%20Diabetes_2025%20(1).pdf - 2026-05-26

Uronate isomerase (EC 5.3.1.12; URI) catalyzes uronate sugar interconversion, a key step in bacterial metabolism, yet its reaction mechanism remains poorly understood. This study delineates the detailed mechanism for the isomerization of d-glucuronate to d-fructuronate catalyzed by a Zn2+-dependent URI enzyme (from Bacillus halodurans). Using quantum mechanical (QM) cluster calculations, three mec

ImportanceGuidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer.ObjectivesTo investigate if targeted hypothermia, compared with targeted normothermia with early treatment of fever, affects functional outcome focusing on societal participation or cognitive functioning at 24 months in initially comatose OHCA survivImportanceGuidelines for temperature control following out-of-hospital cardiac arrest (OHCA) are based on trials with end points of 180 days or fewer.ObjectivesTo investigate if targeted hypothermia, compared with targeted normothermia with early treatment of fever, affects functional outcome focusing on societal participation or cognitive functioning at 24 months in initially comatose OHCA surviv

Smart grids are widely promoted as efficient, low-carbon solutions for energy transitions, yet their governance often treats digital infrastructure as immaterial and uniformly beneficial. This obscures the material, temporal, and justice dimensions that shape real-world outcomes. We introduce Circular Grid Governance (CGG), a framework that integrates circular-economy principles, lifecycle thinkin

INTRODUCTION: Autoantibodies against insulin (IAA) are early appearing markers of autoimmunity against the pancreatic islet beta cells and predict progression to type 1 diabetes if additional islet autoantibodies also develop. It is still controversial if proinsulin rather than insulin is the primary autoantibody.METHODS: The aim of the present study was to compare the half-maximal concentration (

Both high-mountain rivers and wet-based mountain glaciers are considered effective erosion agents. They acted alternatively or simultaneously during the late Quaternary in the Tatra Mountains (West Carpathians) thus producing a vast amount of clastic material that was subject to deposition, reworking and transportation downstream. A small fraction of that amount of the material is still preserved

The genetic changes underlying the development and progression of male breast cancer are poorly understood. Germline BRCA2 mutations account for a significant part of male breast cancer, but the majority of patients lack a known inherited predisposition. We recently demonstrated that the progression of breast cancer in female carriers of a germline BRCA1 or BRCA2 mutation follows specific genetic

Optimization of hexyl-beta-glycoside synthesis from lactose in hexanol at low water activity and high temperature was investigated using beta-glycosidases from hyperthermophilic organisms: Sulfolobus solfataricus (LacS) and Pyrococcus furiosus (CelB). The method for water activity adjustment by equilibration with saturated salt solutions was adapted for use at high temperature. The influence of en

We examined the association between self-reported consumption of fruits and vegetables and prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition (EPIC). Data on food consumption and complete follow-up for cancer incidence were available for 130,544 men in 7 countries recruited into EPIC between 1993 and 1999. After an average of 4.8 years of follow-up, there were

The aim was to determine whether outcome of unrelated donor transplantation for severe aplastic anemia has improved in recent years and whether this is due to patient selection or better transplant technology. We analyzed 498 patients transplanted during 1990-2005. By running univariate regression models dichotomizing year of transplantation we defined 1998 as the year of the most significant chan

Background: Data regarding the association between lipoprotein-associated phospholipase A2 (Lp-PLA(2)) level and incidence of cardiovascular (CV) events are conflicting. This prospective urban population-based study explored the relationship between baseline Lp-PLA(2) activity and mass, respectively, levels and incidence of first coronary heart disease (CHD) and ischemic stroke, respectively. Meth