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Type 2 diabetes (T2D) is a complex, metabolic disorder characterized by hyperglycaemia because of defects in insulin secretion and sensitivity. The rapid increase in T2D is likely to reflect the influence of both genetic and environmental factors in disease development. However, the genetic aetiology of T2D remains largely unknown. Thus, the aim of this thesis was to study the role of genetic vari

Preskription innebär ett utsläckande av möjligheten att med rättsliga medel utkräva prestation enligt avtal. Reglerna om allmän preskription i den svenska rätten finns i Preskriptionslag (1981:130). Enligt denna är preskriptionstiden generellt 10 år. Preskriptionstiden kan dock förlängas genom så kallade preskriptionsavbrott, vilka kan åstadkommas av både borgenär och gäldenär. Borgenären kan väck

BACKGROUND: Persistent organic pollutants (POPs), such as PCBs, DDT and dioxins have in several cross-sectional studies shown strong associations with type 2 diabetes mellitus. Reversed causality can however not be excluded. The aim of this case-control study was to evaluate whether POPs concentration is a risk factor for type 2 diabetes. METHODOLOGY/PRINCIPAL FINDINGS: A case-control study was pe

In this talk recent progress in studying the short-distance properties of the hadronic light-by-light contribution to the muon g−2 is described. The intermediate and short-distance part contributes a large part of the error of the theoretical prediction as described in the white paper [1]. We showed that the massless quark-loop is the first term in a systematic expansion at short-distances, a resu

Hexokinase 2 (Hxk2p) from Saccharomyces cerevisiae is a bi-functional enzyme being both a catalyst and an important regulator in the glucose repression signal. In the presence of xylose Hxk2p is irreversibly inactivated through an autophosphorylation mechanism, affecting all functions. Consequently, the regulation of genes involved in sugar transport and fermentative metabolism is impaired. The ai

Popular Abstract in Swedish Typ 2 diabetes (även kallat sockersjuka eller åldersdiabetes) är en av våra vanligaste förekommande folksjukdomar och ungefär 5% av alla människor beräknas ha sjukdomen. Typ 2 diabetes karakteriseras av kroniskt förhöjda blodsocker-nivåer som orsakas dels av en oförmåga hos insulin att befrämja blodsockerupptag i dess målvävnader, fett och muskel, och dels av en oförmågType 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. The aim of thesis was to identify genetic risk factors for type 2 diabetes. In a g

Popular Abstract in Swedish Diabetes är en folksjukdom och dess förekomst ökar dramatiskt över hela världen. Typ 2 diabetes, eller åldersdiabetes, är den i särklass vanligaste varianten av diabetes. Typ 2 diabetes är starkt förknippat med övervikt och fetma vilket illustreras av att ca 90 % av alla typ 2 diabetiker är överviktiga. Typ 2 diabetes kan förhindras genom livsstilsförändringar. Många mäThere is currently a dramatic and global increase in obesity, type 2 diabetes (T2D) and associated metabolic disorders. T2D can be delayed or prevented in individuals at risk and identifying and developing new food concepts for the prevention of obesity and T2D is of utmost importance. This thesis describes our work on exploring new food concepts for the prevention of T2D. We have used 3T3-L1 adip

We identify biomarkers for disease progression in three type 2 diabetes cohorts encompassing 2,973 individuals across three molecular classes, metabolites, lipids and proteins. Homocitrulline, isoleucine and 2-aminoadipic acid, eight triacylglycerol species, and lowered sphingomyelin 42:2;2 levels are predictive of faster progression towards insulin requirement. Of ~1,300 proteins examined in two

The rising prevalences of type 2 diabetes and obesity constitute major threats to human health globally. Powerful social and economic factors influence the distribution of these diseases among and within populations. These factors act on a substrate of individual predisposition derived from the composite effects of inherited DNA variation and a range of environmental exposures experienced througho

Quest2ROS2 is an open-source ROS2 framework for bi-manual teleoperation designed to scale robot data collection. Extending Quest2ROS, it overcomes workspace limitations via relative motion-based control, calculating robot movement from VR controller pose changes to enable intuitive, pose-independent operation. The framework integrates essential usability and safety features, including real-time RV

Hur ska rampen luta? Formativ undervisning i fysik – systematiska undersökningar NINA AHOKAS OCH LUKASZ MICHALAK NRCF – NATIONELLT RESURSCENTRUM FÖR FYSIK Planering • Introduktion 15 min • Uppgift 1: Lutande planet • Praktiskt arbete 30 min • Erfarenheter 10 min • Fysiken i uppgiften 10 min • Uppgift 2: Elektricitet 10 min • Frågor och kommentarer 10 min • Utvärdering 5 min I systematiska undersök

https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2026-06/STEM%20UP%20Formativ%20undervisning.pdf - 2026-07-19