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Double minutes (dmin)-circular, extra-chromosomal amplifications of specific acentric DNA fragments-are relatively frequent in malignant disorders, particularly in solid tumors. In acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), dmin are observed in similar to 1% of the cases. Most of them consist of an amplified segment from chromosome band 8q24, always including the MYC gene. B
The most complete and realistic physiological data are derived from direct measurements during human experiments; however, they present some limitations such as ethical concerns, time and cost burden. Thermophysiological models are able to predict human thermal response in a wide range of environmental conditions, but their use is limited due to lack of validation. The aim of this work was to vali
In neuroblastoma (NB) patients, minimal residual disease (MRD) can be detected by real-time quantitative PCR (qPCR) using NB-specific target genes, such as PHOX2B and TH. However, it is unknown whether the mRNA levels of these targets vary either during treatment or at relapse. If marker genes are not stably expressed, estimation of MRD levels in bone marrow (BM) or peripheral blood will be hamper
Saccharomyces cerevisiae has emerged as a versatile platform for whole-cell biocatalysis, owing to its intrinsic regeneration of cofactors and amenability to genetic engineering. However, efficient reductive amination of aromatic carbonyls remains challenging due to competing redox pathways and product inhibition by pyruvate. Building on the redox-rewired TMB4133 strain (∆gpd1,2) that accumulates
Systolic tissue Doppler measurements (s') have been used to measure the velocity in myocardial motion and are a valuable tool for evaluating the systolic function of the left and right ventricles. Digestion of food is known to significantly alter hemodynamics and may therefore affect s'. The effect of food intake on s' parameters has not yet been studied. We assessed whether s' is affected by food
The growing need for human-machine interfaces (HMIs) underscores the importance of sensory feedback, with electrical stimulation offering efficient interaction in various applications. While its sensory effects are extensively studied, investigations into the reaction time (RT) following transcutaneous electrical stimulation (TES) remain limited. This study aimed to evaluate how stimulation parame
The current paper presents the results of behavioural observations in a field experiment with automated shuttles in Oslo, Norway. Video observations were conducted at five fixed locations along a challenging 1.2 km automated shuttle line with varying traffic conditions. Observed interactions between vulnerable road users and automated shuttles were coded using a predefined codebook, which allowed
Background: Congestion is associated with poor prognosis in cardiac amyloidosis (CA). The cardio-hepatic interaction and the prognostic impact of secondary liver affection by cardiac congestion in CA are poorly understood and require further characterisation. Methods: Participants of the amyloidosis cohort study AmyKoS at the Interdisciplinary Amyloidosis Centre of Northern Bavaria with proven tra
Sialylations are post-translational modifications of proteins and lipids that play important roles in many cellular events, including cell-cell interactions, proliferation, and migration. Tumor cells express high levels of sialic acid (SA), which are often associated with the increased invasive potential in clinical tumors, correlating with poor prognosis. To overcome the lack of natural SA-recept
Cutibacterium acnes is one of the most abundant bacteria on the skin. Being exposed to oxygen and oxic stress, the secretion of the bacterial antioxidant protein RoxP ensures an endogenous antioxidant system for the preservation of skin health. To investigate the impact of the antioxidant RoxP on oxidation of the bacteria, wildtype and an isogenic roxp mutant were cultured in anaerobic and oxic co
The transcription factor SOX2 is a well-established and important stem cell marker. Its role in cancer biology remains unclear, but it has been proposed to also be a marker of cancer stem cells. We investigated the role of SOX2 protein expression in women with high-grade serous ovarian cancer (HGSOC) to determine its potential prognostic and treatment predictive value. We constructed a tissue micr
Microsoft Word - Gu¨ldemann Fiedler 2021 Workshops.doc 1 Lund online workshop on gender, noun class and classifier systems 12/3/2021 The multiple challenges of Niger-Congo “noun classes” Tom Güldemann1,2 and Ines Fiedler1 Humboldt-Universität zu Berlin1 and MPI for Evolutionary Anthropology Leipzig2 1 The project “Noun classification systems in Africa between gender and nominal declension/‘derifle
Incoming Students As an exchange students you are expected to study full-time, 30 ECTS/semester, of which you must study one mandatory course at Malmö Academy of Music. You may include external courses at other faculties in your application, but you are neither prioritized nor guaranteed admission outside Malmö Academy of Music. If you are interested in studying more than 30 ECTS, please check wit
https://www.mhm.lu.se/en/course-catalogue-autumn-semester - 2026-07-21
Microsoft Word - Abeta and a-syn production (Protein production) 2019.docx Protein production 1. Short description of the platform Expression (in E coli) and purification to ultra-high purity of α-synuclein and amyloid β peptide (Aβ40 and Aβ42). All three proteins are made as wt and mutants, mostly natural abundance but sometimes with stable isotopes (13C,15N). Monomer is isolated in the morning o
https://www.multipark.lu.se/sites/multipark.lu.se/files/abeta_and_a-syn_production_protein_production_report_2019.pdf - 2026-07-23
Emotion and perception are expressed in every language, but their linguistic analysis is surprisingly sparse at typological level. In this paper, an initial attempt is made to describe typological characteristics of emotion and perception and form an initial classification.
Verbal constructions expressing emotion and perception normally have a slightly different argument structure in comparis
Professor Contact details Email: ebbe [dot] nordlander [at] chem [dot] lu [dot] se Phone: +46 46 222 81 18Organisation Chemical Physics Service point: 1 WebpageEbbe Nordlanders profile in Lund University research portalOther affiliations Profile area member Lund Laser Centre, LLC Profile area member LTH Profile Area: Photon Science and Technology Profile area member LU Profile Area: Light and Mate
https://www.chemphys.lu.se/ebbe-nordlander - 2026-07-22
Introduktion:Studiet af performance er i kulturteoretisk sammenhæng karakteriseret ved, at det på én og samme tid peger på et genstandsfelt og på et analytisk perspektiv. Iscenesættelse, materialenærhed, proces, deltagelse, subversion, gentagelse og transformation er ikke kun centrale begreber i forståelsen af performancekunst som felt, men er det også når performanceperspektivet anvendes som anal
