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Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

Efficacy of T-cell assays for the diagnosis of primary defects in cytotoxic lymphocyte exocytosis

Primary hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder associated with autosomal recessive variants in genes required for perforin-mediated lymphocyte cytotoxicity. A rapid diagnosis is crucial for successful treatment. Although defective cytotoxic T lymphocyte (CTL) function causes pathogenesis, quantification of natural killer (NK)–cell exocytosis triggered by K562 targe

Potentialities of manganese ore and iron-carbon particles for pharmaceuticals and personal care products removal in electroactive constructed wetland

This study explores the use of manganese ore, iron-carbon particles (Fe-C), and gravel as anode fillers in electroactive constructed wetlands (ECWs) to treat wastewater containing pharmaceuticals and personal care products (PPCPs) including ciprofloxacin (CIP), ofloxacin (OFL), and naproxen (NPX), while also assessing bioelectricity production. Although the presence of PPCPs reduced pollutant remo

Development and validation of a novel Simoa assay for NPTX2 in Alzheimer's disease and Down syndrome

INTRODUCTION: Synaptic dysfunction and loss are pathological hallmarks of neurodegenerative diseases. Neuronal pentraxin 2 (NPTX2), a presynaptic protein involved in synaptic plasticity, has been linked to cognitive decline in Alzheimer's disease (AD) and other neurodegenerative disorders. METHODS: We developed and validated a novel single molecule array (Simoa) for NPTX2 in cerebrospinal fluid, w

Energy transfer in the peridinin-chicrophyll protein complex reconstituted with mixed chlorophyll sites

We use femtosecond transient absorption spectroscopy to study chlorophyll (Chl)-Chl energy transfer in the peridinin-chlorophyll protein (PCP) reconstituted with mixtures of either chlorophyll b (Chlb) and Chld or Chla and bacteriochlorophyll a (BChla). Analysis of absorption and transient absorption spectra demonstrated that reconstitution with chlorophyll mixtures produces a significant fraction

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Master’s Dissertation Structural Mechanics INFLUENCE OF ANNUAL RING ORIENTATION ON COMPRESSION STRENGTH PERPENDICULAR TO GRAIN IN GLULAM Report TV SM -5203 PH ILIP W A LLIN IN FLU EN C E O F A N N U A L R IN G O R IEN TA TIO N O N C O M PR ESSIO N STR EN G TH PER PEN D IC U LA R TO G R A IN IN G LU LA M PHILIP WALLIN 5203HO.indd 15203HO.indd 1 2015-06-23 15:03:362015-06-23 15:03:36 DEPARTMENT OF C

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5203.pdf - 2026-05-18

Syllabi and reading lists

Spring Semester 2021 Semester 2 SMMV21 Methods in Social Sciences (15 credits) Syllabus Reading list For specialisation Culture and Creativity Management SMMX22 Service Development and Entrepreneurship (15 credits) Syllabus Reading list For specialisation Retail SMMV23 Service Logistics (7.5 credits) Syllabus Reading list Examiner SMMV24 Retail Marketing: Theoretical Perspectives and Concepts (7.5

https://www.ses.lu.se/en/education/study-information/syllabi-and-reading-lists/syllabi-and-reading-lists-15 - 2026-05-19

Syllabi and reading lists

Spring Semester 2022 Semester 2 SMMV21 Methods in Social Sciences (15 credits) Syllabus Reading list For specialisation Culture and Creativity Management SMMX22 Service Development and Entrepreneurship (15 credits) Syllabus Reading list For specialisation Retail SMMV23 Service Logistics (7.5 credits) Syllabus Reading list SMMV24 Retail Marketing: Theoretical Perspectives and Concepts (7.5 credits)

https://www.ses.lu.se/en/education/study-information/syllabi-and-reading-lists/syllabi-and-reading-lists-17 - 2026-05-19

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

Verksamhetsberattelse 2017 for eds nordic user group

Bilaga 1 Verksamhetsberättelse 2017 för EDS Nordic User Group Vid EDS Nordic User Groups årsmöte 2017-03-22 i Luleå valdes följande styrelsemedlemmar: ordförande Cilla Öhnfeldt, Stockholms universitet (omval), Per Falk, Högskolan i Gävle (nyval), Ann- Christin Persson, Lunds universitet (nyval), Tove Andersson, Region Skåne (nyval), Mikael Arvidsson, Karlstads universitet (omval) och Eva Sejmyr, L

https://www.ub.lu.se/sites/ub.lu.se/files/verksamhetsberattelse_2017_for_eds_nordic_user_group.pdf - 2026-05-20

Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells

Definitive hematopoiesis emerges via an endothelial-to-hematopoietic transition in the embryo and placenta; however, the precursor cells to hemogenic endothelium are not defined phenotypically. We previously demonstrated that the induction of hematopoietic progenitors from fibroblasts progresses through hemogenic precursors that are Prom1+Sca1+CD34+CD45- (PS34CD45-). Guided by these studies, we an

2024 VT_LP2 FMAN25 CEQ Course evaluation ver 9.0 (2021-01-23) LTH

2024 VT_LP2 FMAN25 CEQ Course evaluation ver 9.0 (2021-01-23) LTH Course evaluation report - CEQ, FMAN25 Basic facts Course name Calculus of Variations Course code FMAN25 ECTS credits 7.5 hp Year 202324 Study period the course was finishedVT_LP2 Programme all Registrated students 37 Number answers and response rate 5 / 14 % Number answers from males 2 Number answers from females 2 Study hours acco

https://www.maths.lu.se/fileadmin/maths/Matematik_NF/Kursutvaerderingar/VT2024/MATC25FMAN25VT24.pdf - 2026-05-18

Syllabi and reading lists

Spring Semester 2023 Semester 2 SMMX21 Methods in Social Sciences (15 credits) Syllabus Reading list Examiner For specialisation Culture and Creativity Management SMMX22 Service Development and Entrepreneurship (15 credits) Syllabus Reading list Examiner For specialisation Retail SMMV23 Service Logistics (7.5 credits) Syllabus Reading list Examiner SMMV24 Retail Marketing: Theoretical Perspectives

https://www.ses.lu.se/en/education/study-information/syllabi-and-reading-lists/syllabi-and-reading-lists-19 - 2026-05-19

Syllabi and reading lists - Cloned

Spring 2022 Semester 2 SMMV21 Methods in Social Sciences (15 credits) Syllabus Reading list Examiner For specialisation Culture and Creativity Management SMMX22 Service Development and Entrepreneurship (15 credits) Syllabus Reading list Examiner For specialisation Retail SMMV23 Service Logistics (7.5 credits) Syllabus Reading list Examiner SMMV24 Retail Marketing: Theoretical Perspectives and Conc

https://www.ses.lu.se/en/syllabi-and-reading-lists-cloned - 2026-05-19