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Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel

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Abstract in French La géométrie du tissue urbain a une grande influence sur le microclimat et influence donc le confort thermique extérieur des habitants et, le microclimat urbain influence à son tour indirectement le climat intérieur. Une mauvaise adaption climatique des environnements urbains a souvent pour conséquence l'utilisation d'une climatisation active et ainsi une augmentation de la cons

Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis

To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities

In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha

Purification of streptococcal protein G expressed by Escherichia coli by high performance liquid affinity chromatography using immobilized immunoglobulin G and albumin

A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz

Antibody-dependent allostery of the M1 protein

Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

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Alors, Nous allons dans une petite voyage en Italie, un pays trés jolie et trés haut. Ma petite souer arrivé avec moi aussi. Nous voyager avec ma voiture qui est trés petite. Ma soeur dis: - Nous avons un probléme maintenant.. - Qu´est que c´est ?, je dis. - Les valise est trop gros pour ta voiture. - Merde ! Nous allons avec quattre valises, deux valises pour moi et deux pour ma souer. Nous achet

https://projekt.ht.lu.se/fileadmin/user_upload/project/cefle/textes/le_sous-corpus_transversal/stade_b/Bernt.txt - 2026-05-16

Huvudrubrik

Huvudrubrik ‹# › Bli medlem i ett Saco-S-förbund Bli medlem i ett Saco-S-förbund 1 Bli medlem i ett Saco-S-förbund 1 Bli medlem i ett Saco-S-förbund Bli medlem i ett Sacoförbundwww.saco-s.se ‹# › Bli medlem i ett Saco-S-förbund Bli medlem i ett Saco-S-förbund • Säkerställa verksamhetens kvalitet och individuella resultat • säkerställa att SLU kan bemanna uppdrag med rätt person och rätt kompetens

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/slu/dokument/medarbetarsamtal-vid-slu-230322.pdf - 2026-05-17

Från förening till företag - Sportslig kontra ekonomisk framgång

Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser

Antenna protein composition of PS I and PS II in thylakoid sub-domains

Spinach thylakoids were separated into grana core, grana margin, and two different stromal lamella fractions in the absence of detergents. The levels of all light-harvesting chlorophyll a/b-binding (LHC) proteins were determined in all fractions, and were normalised to the amount of Photosystem I (PS I) and Photosystem II (PS II) centres. PS Iβ in the stroma lamellae was found to have a full compl

Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform

Delivery of antigenic peptides to antigen presenting cells (APCs) such as dendritic cells (DCs) using monoclonal antibodies (mAbs) is an attractive approach to evoke antigen-specific T cell activation and improve drug efficacy. Peptide linkage to mAbs has previously been achieved through genetic fusion, chemical conjugation, nano-engineered platforms and high affinity peptides. In this study, we h

Prekonceptionell halsa 20181218

Prekonceptionell hälsa och rådgivning Kvinnor och mäns levnadsvanor inför graviditet påverkar fostret och det blivande barnets hälsa. Under våren 2019 ges en utbildning i Prekonceptionell hälsa och rådgivning vid Lunds universitet. Utbildningen är den första kursen i Sverige inom prekonceptionell hälsa, vilket gör den unik i sitt slag. Den riktar sig till barnmorskor generellt, och i synnerhet til

https://www.medicin.lu.se/sites/medicin.lu.se/files/prekonceptionell_halsa_20181218.pdf - 2026-05-17

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Methane and carbon dioxide fluxes over a lake : Comparison between eddy covariance, floating chambers and boundary layer method

Freshwaters bring a notable contribution to the global carbon budget by emitting both carbon dioxide (CO2) and methane (CH4) to the atmosphere. Global estimates of freshwater emissions traditionally use a wind-speed-based gas transfer velocity, kCC (introduced by Cole and Caraco, 1998), for calculating diffusive flux with the boundary layer method (BLM). We compared CH4 and CO2 fluxes from BLM wit

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Justification and Theosis (deification) The Joint Declaration on Justification and the Dialogue between East and'West Gösta Hallonsten (Jniversidade de Lund - Suécia 248 Piero Codø reciproco (cf. Gv 13,31-35;15,I2-I3), riflesso e realizzaztone antropologi ca delle relazioni d' amore vissute nella Santissima Trinità, è dunque chiamataa scoprire in Maria il suo archetipo e la sua for- ma generatrice

https://www.ctr.lu.se/media/documents/persons/GostaHallonsten/Justif_Theosis_1.pdf - 2026-05-17

Jiffy press release english

Microsoft Word - Jiffy_press_eng.docx JULIA SJÖLIN JIFFY 3 APRIL–18 APRIL 2020 Julia once told me about a project which point of departure was to collect glass that had been formed by lightning striking sand. The project never happened but the glass and the discharge of energy from which the lightning emerge, still plays a central role in Julia Sjölin's practice and consequently in this exhibition

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/jiffy_press_release_english.pdf - 2026-05-17

Compatibility between Flooring Materials and Concrete

This article outlines an experimental and numerical study on compatibility between flooring materials and concrete. Full-scale cylinders and slabs with different kinds of floorings were tested. The cylinders were studied in the laboratory, and cured in the same way as at a building site. The slabs were ground, treated with plaster and/or untreated (reference concrete). These slabs were water-cured

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Course evaluation Course : Statistical Modelling of Extreme Values:MASM15 Evaluated on LTH: Yes Lecturer: Nader Tajvidi Number of students: 15 Grades 2 VG, 4 G, 9 U Summary: There were some issues regarding the examination of the course due to distance education otherwise the course works well. Comments: The issues related to distance eduation will be resolved the next time the course is given. 1

https://www.maths.lu.se/fileadmin/maths/utbildning_education/KU_Statistical_Modelling_of_Extreme_ValuesMASM15.pdf - 2026-05-16

Engelstalig academisch cv b keymeulen 08.01.2019

Keymeulen B Page 1 KEYMEULEN Bart Date, Place of Birth February 14, 1961, Aalst - Belgium Nationality Belgian Address Diabetes Research Center Vrije Universiteit Brussel Laarbeeklaan 103 B-1090 Brussel, Belgium Tel. 32-2-4774541 Fax. 32-2-4774545 E-mail: Bart.Keymeulen@vub.be Diabeteskliniek UZ Brussel Laarbeeklaan 101 B-1090 Brussel, Belgium Tel. 32-2-477 78 76 Fax. 32-2-477 78 03 E-mail: Bart.Ke

https://www.ludc.lu.se/sites/ludc.lu.se/files/engelstalig_academisch_cv_b_keymeulen_08.01.2019.pdf - 2026-05-17

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit