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Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors

BACKGROUND: Larotrectinib is a first-in-class, highly selective tropomyosin receptor kinase (TRK) inhibitor approved to treat adult and pediatric patients with TRK fusion-positive cancer. The aim of this study was to evaluate the efficacy and safety of larotrectinib in patients with TRK fusion-positive primary central nervous system (CNS) tumors.METHODS: Patients with TRK fusion-positive primary C

Evaluating Sex and Age Differences in ADI-R and ADOS Scores in a Large European Multi-site Sample of Individuals with Autism Spectrum Disorder

Research on sex-related differences in Autism Spectrum Disorder (ASD) has been impeded by small samples. We pooled 28 datasets from 18 sites across nine European countries to examine sex differences in the ASD phenotype on the ADI-R (376 females, 1763 males) and ADOS (233 females, 1187 males). On the ADI-R, early childhood restricted and repetitive behaviours were lower in females than males, alon

A genome-wide association study of IgM antibody against phosphorylcholine : Shared genetics and phenotypic relationship to chronic lymphocytic leukemia

Phosphorylcholine (PC) is an epitope on oxidized low-density lipoprotein (oxLDL), apoptotic cells and several pathogens like Streptococcus pneumoniae. Immunoglobulin M against PC (IgM anti-PC) has the ability to inhibit uptake of oxLDL by macrophages and increase clearance of apoptotic cells. From our genome-wide association studies (GWASs) in four Europeanancestry cohorts, six single nucleotide p

Standard set of health outcome measures for older persons

Background: The International Consortium for Health Outcomes Measurement (ICHOM) was founded in 2012 to propose consensus-based measurement tools and documentation for different conditions and populations.This article describes how the ICHOM Older Person Working Group followed a consensus-driven modified Delphi technique to develop multiple global outcome measures in older persons. The standard se

Informing implementation of Nature-based Solutions in marine and coastal environments : the MaCoBioS Blue NBS Toolbox

Interconnected societal challenges such as climate change, biodiversity loss and food security demand immediate and coordinated action across local to global scales, guided by coherent policies and management mechanisms. Reflecting on the critical need to address societal challenges, Nature-based Solutions in marine and coastal environments, known as blue NBS, have emerged as an important part of

International multicentre validation of the left pancreatectomy pancreatic fistula prediction models and development and validation of the combined DISPAIR-FRS prediction model

Background: Every fifth patient undergoing left pancreatectomy develops a postoperative pancreatic fistula (POPF). Accurate POPF risk prediction could help. Two independent preoperative prediction models have been developed and externally validated: DISPAIR and D-FRS. The aim of this study was to validate, compare, and possibly update the models. Methods: Patients from nine high-volume pancreatic

Sacrificial redox modulation by a secreted bacterial effector molecule mitigates oxidative stress and inflammation in vivo

Human-bacterial interactions play a crucial role in several essential aspects of life. Here, we describe how a secreted protein from the skin commensal Cutibacterium acnes, RoxP, functions as a sacrificial redox effector molecule that facilitates beneficial interactions with its human host by counteracting oxidative stress and reducing stress-induced inflammation. Using a combination of structural

PowerPoint-presentation

PowerPoint-presentation Studieteknik för akademiska studier STUDIEVERKSTADEN 2026-01-28 ➢ Studieteknik ➢ Akademiskt skrivande och läsande Studieverkstaden Atli D Sigurdsson Sandra PeterssonFrida Blomberg Cecilie FonnesbechMaria Källqvist Läs mer och boka tid för handledning på vår hemsida: www.lu.se/studieverkstaden Charlotte H Webb Utbud och resurser • Digitala resurser • Föreläsningar • Studietr

https://www.sol.lu.se/fileadmin/user_upload/sol/utbildning/Dokument/Studieteknik_SOL_2026-01-28.pdf - 2026-05-09

Alla nyheter – Sida 4 – Vetenskap och Hälsa

Alla nyheter – Sida 4 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Äldre barn mår sämst av hemlöshet 2025-12-12 Flertalet barn och unga i hemlöshet mår psykiskt och fysiskt dåligt. Annelie Björkhagen Turesson, forskare vid Malmö universitet, har intervjuat både hemlösa barn i Malmö och

https://www.vetenskaphalsa.se/alla-nyheter/page/4/ - 2026-05-09

Course Evaluations, Mathematics, Faculty of Science

Course Evaluations, Mathematics, Faculty of Science | Centre for Mathematical Sciences Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. The

https://www.maths.lu.se/english/education/courses/course-evaluations/course-evaluations-numerical-analyses-at-faculty-of-science/ - 2026-05-09

No title

1 3 February 2021 Management Response External Evaluation of the Raoul Wallenberg Institute Turkey Human Rights Capacity Development Programme, 2015-2020 Background In July 2020, the Raoul Wallenberg Institute of Human Rights and Humanitarian Law (RWI) commissioned an external evaluation of its Turkey Human Rights Capacity Development Programme 2015-2020 (the Programme) to assess the effectiveness

https://rwi.lu.se/wp-content/uploads/2022/04/Management-Response-to-Evaluation-final-002.pdf - 2026-05-09

No title

BACKGROUND BRIEF Key International Standards and Guidelines Relating to Displacement in the Context of Disasters and Climate Change Regional Asia Programme Report - Funded by Sida Title Written by Dr Matthew Scott* 2019 *Senior researcher and head of the People on the Move thematic area, Raoul Wallenberg Institute of Human Rights and Humanitarian Law (www.rwi.lu.se) http://www.rwi.lu.se TABLE OF C

https://rwi.lu.se/wp-content/uploads/2024/03/Key-International-Standard-and-Guidelines-Relating-to-Displacement.pdf - 2026-05-09

Rapport_Lönepremier för utbildning2.indd

Rapport_Lönepremier för utbildning2.indd Lönepremier för utbildning – Utveckling under 2000-talet 2 Sammanfattning Denna rapport granskar lönepremien för högskoleutbildning perioden 2001–2020. Högskolepremien har minskat och är lägre nu än den var i början av 2000-talet. Framför allt är utvecklingen negativ inom privat och statlig sektor. Högskole- premien ökar något de senaste åren, men det är

https://www.saco.se/globalassets/bilder-video-och-dokument/sacos-rapporter/2022/rapport_lonepremier-for-utbildning_webb.pdf - 2026-05-10

Blodet och immunförsvaret – Sida 6 – Vetenskap och Hälsa

Blodet och immunförsvaret – Sida 6 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kategori: Blodet och immunförsvaret Det här behöver du veta om sepsis 2018-11-06 – Trots att sepsis är ett livshotande tillstånd, är det många som inte hört talas om det. Ändå är det relativt vanligt. Det sä

https://www.vetenskaphalsa.se/kategori/blodet-och-immunforsvaret/page/6/ - 2026-05-10

Resistenta bakterier – smittad vid utlandsresan? – Vetenskap och Hälsa

Resistenta bakterier – smittad vid utlandsresan? – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Resistenta bakterier – smittad vid utlandsresan? 2012-06-05 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Johan Tham med sina kollegor Nathalie Nilsson och Des

https://www.vetenskaphalsa.se/resistenta-bakterier-smittad-vid-utlandsresan/ - 2026-05-10

Feature – Sida 11 – Vetenskap och Hälsa

Feature – Sida 11 – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Kategori: Feature Tema: Säkrare diagnos – effektivare behandling 2015-06-08 Foto: Roger Lundholm Att så tidigt som möjligt kunna ställa rätt diagnos kan vara avgörande för den som drabbats av sjukdom. Oavsett om det är en li

https://www.vetenskaphalsa.se/kategori/feature/page/11/ - 2026-05-10

GenderintheMENA Programme 202104[36]

Gender and Politics in the Middle East and North Africa: A Decade after the Arab Uprisings May 6, 7, 20, & 21, 2021 Virtual Workshop Ellen Lust, Program on Governance and Local Development, University of Gothenburg Marwa Shalaby, University of Wisconsin-Madison Lena Wägnerud, Quality of Government Institute, University of Gothenburg Hosted by The Program on Governance and Local Development at the

https://www.cmes.lu.se/sites/cmes.lu.se/files/2021-05/GenderintheMENA_Programme_202104%5B36%5D.pdf - 2026-05-10

Understand explain improve

UNDERSTAND, EXPLAIN, IMPROVE THEMATIC COLLABORATION INITIATIVES 2017–2022 EDITOR AND GRAPHIC FORM Bodil Malmström Cooperation office Research, Collaboration and Innovation Lund University TEXT Catrin Jakobsson, Noomi Egan, Bodil Malmström and Pia Romare PHOTO Kennet Ruona, Johan Bävman, Gunnar Menander, Erik Anders- son, Salar Haghighatafshar. Catrin Jakobsson, Bodil Malmström and Shutterstock PRO

https://www.lu.se/sites/www.lu.se/files/understand_explain_improve.pdf - 2026-05-10

Fault Tolerance for Real-Time Systems: Analysis and Optimization of Roll-back Recovery with Checkpointing

Popular Abstract in English In the modern world of today, we are surrounded with many electronic devices which offer previously unseen performance. These devices constitute a large part of the everyday consumer electronics such as laptops, tablets, smart phones, etc., but are also used in wide variety of domains such as automotive industry, avionics, medicine, etc. The constant demand for high perIncreasing soft error rates in recent semiconductor technologies enforce the usage of fault tolerance. While fault tolerance enables correct operation in the presence of soft errors, it usually introduces a time overhead. The time overhead is particularly important for a group of computer systems referred to as real-time systems (RTSs) where correct operation is defined as producing the correct re