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A Screening Tool to Quickly Identify Movement Disorders in Patients with Inborn Errors of Metabolism

BACKGROUND: Movement disorders are frequent in patients with inborn errors of metabolism (IEMs) but poorly recognized, particularly by nonmovement disorder specialists. We propose an easy-to-use clinical screening tool to help recognize movement disorders.OBJECTIVE: The aim is to develop a user-friendly rapid screening tool for nonmovement disorder specialists to detect moderate and severe movemen

New Inhibitors in the Ageing Population : A Retrospective, Observational, Cohort Study of New Inhibitors in Older People with Hemophilia

Introduction A second peak of inhibitors has been reported in patients with severe hemophilia A (HA) aged >50 years in the United Kingdom. The reason for this suggested breakdown of tolerance in the aging population is unclear, as is the potential impact of regular exposure to the deficient factor by prophylaxis at higher age. No data on hemophilia B (HB) have ever been reported. Aim The ADVANCE W

Benefits and harms of high-dose haemodiafiltration versus high-flux haemodialysis : The comparison of high-dose haemodiafiltration with high-flux haemodialysis (CONVINCE) trial protocol

Introduction End-stage kidney disease (ESKD) is a major public health problem affecting more than 2 million people worldwide. It is one of the most severe chronic non-communicable diseases. Haemodialysis (HD) is the most common therapeutic option but is also associated with a risk of cardiovascular events, hospitalisation and suboptimal quality of life. Over the past decades, haemodiafiltration (H

Towards validation of smart cyber-physical systems

Conventional technical system is designed with all details in the product development phase. Conditions of operation and modes of behaviour are known and validated before the product is launched to the market. This deterministic way of thinking is built into regulations procedures and it is requested at validation when safety is an issue. The existing way of validation that is based on predictive

Gene profiling reveals a contact allergy signature in most positive Amerchol L-101 patch-test reactions

Background: Diagnosis of contact allergy (CA) to Amerchol L-101 (AL-101), a marker for lanolin allergy, is problematic. Positive patch-test reactions are frequently doubtful or weakly positive and difficult to associate with clinical relevance. Objective: To gain further insight on the allergic or irritant nature of skin reactions induced by AL-101 patch test. Methods: We re-tested in a dose–respo

Lithium recovery through WS2 nanofillers-promoted solar photothermal membrane crystallization of LiCl

The recovery of raw materials represents one of the greatest challenges for a circular economy. Especially, the increased demand for lithium in the last years for its critical role in Li-ion batteries implies the need for green technology for Li recovery able to address market requests. Here, we devise and implement a new technology exploiting excitons-based light-to-heat conversion promoted by WS

Accurate Indoor Positioning Based on Learned Absolute and Relative Models

To improve the accuracy of indoor positioning systems it can be useful to combine different types of sensor data. This paper describes deep learning methods both for estimating absolute positions and for performing pedestrian dead reckoning, and then how to combine the resulting estimates using weighted least squares optimization. The positioning model is based on a custom neural network which use

Clinicians’ use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors : an international survey

The BOADICEA breast cancer (BC) risk assessment model and its associated Web Application v3 (BWA) tool are being extended to incorporate additional genetic and non-genetic BC risk factors. From an online survey through the BOADICEA website and UK, Dutch, French and Swedish national genetic societies, we explored the relationships between the usage frequencies of the BWA and six other common BC ris

High occurrence of transportation and logistics occupations among vascular dementia patients : An observational study

Background: Growing evidence suggests a role of occupation in the emergence and manifestation of dementia. Occupations are often defined by complexity level, although working environments and activities differ in several other important ways. We aimed to capture the multi-faceted nature of occupation through its measurement as a qualitative (instead of a quantitative) variable and explored its rel

Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes - Proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS

Definite progress has been made in the exploration of myelodysplastic syndromes (MDS) by flow cytometry (FCM) since the publication of the World Health Organization 2008 classification of myeloid neoplasms. An international working party initiated within the European LeukemiaNet and extended to include members from Australia, Canada, Japan, Taiwan and the United States has, through several worksho

Long term safety and visibility of a novel liquid fiducial marker for use in image guided radiotherapy of non-small cell lung cancer

Safety and clinical feasibility of injecting a novel liquid fiducial marker for use in image guided radiotherapy in 15 patients with non-small cell lung cancer are reported. No major safety or toxicity issues were encountered. Markers present at start of radiotherapy remained visible in cone beam computed tomography and fluoroscopy images throughout the treatment course and on computed tomography

Brain Fingerprinting Using FMRI Spectral Signatures On High-Resolution Cortical Graphs

Resting-state fMRI has proven to entail subject-specific signatures that can serve as a fingerprint to identify individuals. Conventional methods are based on building a connectivity matrix based on correlation between the average time course of pairs of brain regions. This approach, first, disregards the exquisite spatial detail manifested by fMRI due to working on average regional activities, se

Vem du är spelar roll vid återhämtning efter en hjärtinfarkt – Vetenskap och Hälsa

Vem du är spelar roll vid återhämtning efter en hjärtinfarkt – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Vem du är spelar roll vid återhämtning efter en hjärtinfarkt 2016-02-17 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Din personlighetstyp och hur

https://www.vetenskaphalsa.se/vem-du-ar-spelar-roll-vid-aterhamtning-efter-en-hjartinfarkt/ - 2026-04-21

Foreign language perceptual curiosity : construct, measurement, and applications

Learning a language is a creative process. It involves novelty and imagination. While curiosity can be highly beneficial, research is limited. Studies so far conducted have explored epistemic curiosity as a trait-like disposition. In contrast, the current study focuses on perceptual curiosity (PC). PC is a situational response evoked by novelty, complexity and ambiguities in sensory stimulation. P

MIRD Pamphlet No. 32 : A MIRD Recovery Coefficient Model for Resolution Characterization and Shape-Specific Partial-Volume Correction

Accurate quantification in emission tomography is essential for internal radiopharmaceutical therapy dosimetry. Mean activity concentration measurements in objects with diameters less than 10 times the full width at half maximum of the imaging system’s spatial resolution are significantly affected (>10%) by the partial-volume effect. This study develops a framework for PET and SPECT spatial resolu