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Ion beam methods are used to analyse material (Ion Beam Analysis, IBA) and to modify the target (Ion Beam Modification of Materials, IBMM). In this thesis, ion beams have been used in various IBA techniques to investigate the surface nanometre structures, and also in an ion beam synthesis (IBS) technique to form thin films and to modify material properties. The work is divided into two main parts:
Popular Abstract in Swedish Elakartade (maligna) blodsjukdomar uppstår i den blodbildande benmärgen, vilken är innesluten i hålrummen i de skelettdelar som kan sägas täckas av en badmössa och en gammaldags baddräkt. En av de celltyper som bildas i benmärgen är plasmacellen, en vit blodkropp som utgör mindre än 2% av benmärgscellerna och som tillverkar specifika antikroppar vid infektioner. Vid monAcquired genetic changes have proved to be of diagnostic and prognostic importance in different hematologic malignancies as well as in some solid tumor types. However, although multiple myeloma (MM), an incurable disease, and its proceeding stage monoclonal gammopathy of undetermined significance (MGUS) are quite common, little is known about the karyotypic features of these plasma cell dyscrasias
Popular Abstract in Swedish För att en organism ska fungera är det nödvändigt att alla de celler som bygger upp organismen kommunicerar med varandra. Denna kommunikation sker genom att speciella proteiner på cellens yta, s.k. receptorer, tar emot signaler från andra celler. G-proteinkopplade receptorer (GPCR) är den vanligaste typen av receptorer. Då en signalmolekyl binder till en GPCR ändrar deIn all higher organisms, there is a need for intercellular communication. G-protein coupled receptors (GPCRs), located on the cell surface, play an important role in this communication. Cells synthesize and release signalling molecules (ligands), which produce a specific response only in those cells that have a receptor for that ligand. The total number of GPCRs is estimated to be around 800 where
The first part of the investigation is related to the heat transfer and fluid flow problem inside ribbed ducts with a square cross section. The typical applications of this problem are in the cooling of gas turbine blades and guiding vanes. The second part is related to application of intercoolers in gas turbine systems. The intercooling is performed via intercoolers that usually are water-air hea
Popular Abstract in Swedish Recenta dödismiljöer framför Brúarjökull-glaciären på Island och Holmströmbreen på Svalbard har undersökts med speciellt fokus på landforms- och sedimentgenes samt kvantifiering av dödisavsmältningen. Fältmätningar, studier av tidsserier av flyg? och satellitbilder samt digitala terrängmodeller är dataunderlaget för kvantifieringen av dödisavsmältningen. SedimentologiskModern dead-ice environments in the glacier forefields of Brúarjökull, Iceland and Holmströmbreen, Svalbard were investigated with focus on landform and sediment genesis, as well as quantification of melting. Field monitoring and studies of multi-temporal aerial photographs, satellite imagery, and Digital Elevation Models (DEMs) provided data for the melting quantification. Sedimentological and ge
Combining data from spontaneous face-to-face conversations in the London-Lund Corpus (LLC) of spoken British English and a laboratory experiment, this paper analyses the dynamic nature of I think constructions in dialogue. We make use of the functional category of ENGAGEMENT in APPRAISAL theory as an analytical tool (Martin & White, 2005). More precisely, we examine whether I think constructio
BACKGROUND: Patellofemoral arthroplasty (PFA) is one option for the treatment of isolated patellofemoral osteoarthritis, but there are limited data regarding the procedure and results. Because isolated patellofemoral arthritis is relatively uncommon, available case series generally are small, and even within national registries, sample sizes are limited. Combining data from multiple registries may
The isoxazol leflunomide (N-(4-trifluoromethylphenyl)-5-methylisoxazol-4-carboxamide) and its active metabolite A77-1726 (N-(4-trifluoromethyl)-phenyl-2-cyano-3-hydroxy-crotonic acidamide) are promising disease-modifying antirheumatic drugs now in clinical trials. The malononitrilamides MNA279 (2-cyano-3-cyclopropyl-3-oxo-(4-cyanophenyl)propionamide) MNA715(N-(4-trifluoromethyl)-phenyl-2-cyano-3-h
The present study recorded 36 genera and 115 species of the lichen family Teloschistaceae in India. Three species, i.e. Caloplaca rajasthanica S. Y. Kondr., Upreti et G. P. Sinha, Huriella upretiana S. Y. Kondr., G. K. Mishra, Nayaka et A. Thell, and Squamulea uttarkashiana S. Y. Kondr., Upreti, Nayaka et A. Thell, are described as new species. Seven new combinations, i.e. Fulgogasparrea awasthii
In 1997-2003, a protocol for treatment of acute myeloid leukaemia (AML) (except promyelocytic leukaemia) was activated in four Swedish health care regions covering 50% of the national population. Based on cytogenetics and clinical findings, patients aged 18-60 yr were assigned to one of three risk groups. In this report we account for the long-term clinical outcome of enrolled patients. Patients r
The subject of this dissertation is the regulation of banks. The enquiry is built around three overreaching research questions:1. What is a bank?2. Why do banks have to be regulated?3. How should banks be regulated? Each of these three questions is dedicated a separate and comprehensive section, each consisting of several chapters. Even though the subject is jurisprudence, the perspective of the
Vocabulary for subsistence and technology may vary a great deal in their degree of borrowability, depending on time, place, inherent subsistence and technology, and the situation of the borrowing. In cross-linguistic typological studies of borrowability, these words tend to group somewhere from middle to high in borrowability, depending on lexical concept (Haspelmath & Tadmor, 2009).We have co
Basque is spoken by approximately 660,000 people (Trask 1997) in the Basque Country, straddling the border between northern Spain and southern France, particularly in rural areas of the Bizkaia and Gipuzkoa coastline, as well as inland Gipuzkoa and the foothills of the Pyrenees in Navarre. Virtually all Basque speakers are bilingual with either Spanish or French. Nevertheless, Basque is, due to it
“The implications and applications of biotechnology continue to be at the centre of public debate. In the light of rapid scientific advances and novel insights, the multi-faceted discussions are particularly fierce with regard to patents on DNA–related technology. In the often very emotionally-led debate basically two directly conflicting schools of thoughts can be identified. Some people believe
Jura novit curia anses innebära att parterna inte kan binda domstolen vid vilken rättsregel som är tillämplig. Och inte heller hur denna rättsregel ska tolkas och tillämpas. Denna princip vållar emellertid vissa problem. Syftet med denna uppsats har varit att utreda om principen om jura novit curias omfattning enligt gällande rätt är välavvägd samt att annars ge förslag på bättre lösningar. PrinciIura novit curia implies that the parties cannot, with binding effect for the court, choose which law should be applied. Nor can they choose how the law should be interpreted or applied. The purpose of this paper was to investigate whether the extent of the principle of iura novit curia in Swedish law is balanced. If not so, the aim is to provide suggestions for a better solution. Iura novit curia
Barnet bästa och barnets vilja är två nyckelbegrepp inom svensk barnrätt. Samspelet mellan begreppen kan vara intressant när frågor om barnets livssituation aktualiseras. I takt med stigande ålder och större mognadsgrad, till-mäts barnets vilja större vikt i enlighet med vad som stadgas i 6 kap. 2a § 3st. FB samt artikel 12 barnkonventionen. I praktiken kan detta medföra att yngre barns vilja bedöThe child's best interest and the child's will are two key concepts in Swedish Child law. The interaction between the two concepts can be interesting when questions about the child's life situation are raised. In line with rising age and greater maturity, the child's will is given greater significance in accordance with what is stipulated in Chapter 6, 2a § 3 subparagraph FB and Ar
The present study examined how statements about depression and suicidal thoughts are responded to on Swedish internet forums. The study was conducted on two public Swedish internet forums and their respective sub-forums focusing on mental illness. A total of 1475 posts in 72 different threads were analysed using thematic analysis with methodological inspiration from grounded theory. Six themes wer
Background and objective: The pharmacokinetics of mycophenolic acid (MPA) are complex, with large interindividual variability over time. There are also well documented interactions with ciclosporin, and assessment of MPA exposure is therefore necessary when reducing or stopping ciclosporin therapy. Here we report on the pharmacokinetic and pharmacodynamic behaviour of MPA in renal transplant patie
