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River flow response to changing electricity demand and centralized hydropower operations in the Paranapanema River basin, Brazil

Study region: The Paranapanema River Basin, located in southeastern Brazil, is characterized by a cascade of large hydropower plants regulated by a nationally coordinated dispatch system. This basin is a representative case of reservoir-regulated rivers in the country, where multiple dams interact to supply electricity while reshaping natural flow regimes. Study focus: This study examines hydropow

MIRD Pamphlet No. 33: MIRDpvc - A Software Tool for Recovery Coefficient-Based Partial-Volume Correction

Partial-volume effects (PVEs) arise from the limited spatial resolution of PET and SPECT imaging systems, causing the systematic underestimation of activity concentration in structures that may hold critical diagnostic, treatment, or dosimetric information that impacts patient management. Recovery coefficient (RC)-based partial-volume correction (PVC) is one of the simpler approaches used to corre

A structured lifestyle intervention to reduce cardiometabolic risk factors in individuals with obsessive-compulsive disorder : feasibility trial

Background Obsessive-compulsive disorder (OCD) is associated with an increased risk of cardiometabolic disorders. We developed a lifestyle intervention, named LIFT, aimed at improving lifestyle habits (physical activity, diet, alcohol and tobacco use, stress, sleep) and reducing cardiometabolic risk factors in OCD. Aims This study aimed to establish the feasibility and acceptability of LIFT, evalu

Cryptic Ontogenetic Changes in the Ventral Coloration of a Color Polymorphic Wall Lizard (Podarcis muralis)

Many animals undergo irreversible ontogenetic color changes (OCCs), yet these changes are often overlooked despite their potential ethological relevance. The problem is compounded when OCCs involve wavelengths invisible to humans. Wall lizards can perceive ultraviolet (UV) light, and their conspicuous ventral and ventrolateral coloration—including UV-reflecting patched—likely serves social communi

Person-Centred Nursing in Allogeneic Stem Cell Transplantation Using a Conversation Tool : A Qualitative Study

Background: Patients undergoing allogeneic haematopoietic stem cell transplantation (allo-HCT) often face complex and evolving needs throughout recovery. Person-centred nursing (PCN) is essential in this context yet remains underexplored in specialised care settings. In Sweden, the Assessment of Rehabilitation Needs Checklist (ARNC) is commonly used in cancer care, but its role in supporting perso

Sea Nomads, Sultans, and Raiders : History and Ethnogenesis in the Sulu Archipelago, Philippines

The Sulu Archipelago, nestled between Mindanao and Borneo, has been a melting pot of people and cultures for thousands of years. Major sociopolitical changes marked its history, attracting groups of people or forcing drastic dispersals. Today, the islands host various ethnolinguistic groups, including Sama-Badjaw and Tausug-speaking communities. We surveyed the literature from multiple disciplines

Recension av Swedish Students at the University of Leipzig in the Middle Ages

The book contains editions and studies of texts produced by Swedish academics active at the University of Leipzig in the fifteenth century. Academic texts from the Middle Ages are difficult to digest; the editions, translations and studies presented in this book and its companion volumes make them as accessible to the modern reader as one can possibly ask.

Comorbidity burden in adult atopic dermatitis : A population-based study

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease that has been shown to be associated with allergic comorbidities. However, studies examining comorbidities in patients with AD are incomplete, which may contribute to suboptimal care. Objectives: The objective was to compare the risk of developing different allergic and nonallergic comorbidities among adult patients with AD

Elective one-minute full brain multi-contrast MRI versus brain CT in pediatric patients : a prospective feasibility study

Background: Brain CT can be used to evaluate pediatric patients with suspicion of cerebral pathology when anesthetic and MRI resources are scarce. This study aimed to assess if pediatric patients referred for an elective brain CT could endure a diagnostic fast brain MRI without general anesthesia using a one-minute multi-contrast EPI-based sequence (EPIMix) with comparable diagnostic performance.

Predicting Perceptual Centers Located at Vowel Onset in German Speech Using Long Short-Term Memory Networks

Perceptual centers (p-centers) can be defined as the perceived centers of a syllable. Previous research regarding the location of p-centers in speech relied on experimental methods, and among the suggested acoustic features contributing to the location of p-centers in Germanic languages is the transition of the consonant to the vowel onset. The current study investigates the prediction of the loca

Binocular field configuration in owls : The role of foraging ecology

The binocular field of vision differs widely in birds depending on ecological traits such as foraging. Owls (Strigiformes) have been considered to have a unique binocular field, but whether it is related to foraging has remained unknown. While taking into account allometry and phylogeny, we hypothesized that both daily activity cycle and diet determine the size and shape of the binocular field in

Haemodynamic effects of fludrocortisone and midodrine in patients with symptoms due to hypotension

AIM: The study aimed to assess the haemodynamic effects of fludrocortisone and midodrine, alone or combined, in patients with recurrent syncope and/or symptoms due to hypotension and ≥ 1 daytime systolic blood pressure (SBP) drop < 90 mmHg or ≥ 2 daytime SBP drops < 100 mmHg recorded by 24-h ambulatory blood pressure monitoring (ABPM1).METHOD: A total of 53 patients (mean age, 40.9 ± 18.5 years, 3

Beneficial Effects of a Moderately High-Protein Diet on Telomere Length in Subjects with Overweight or Obesity

Background and aim: Telomere length (TL) is a key biomarker of cellular aging, with shorter telomeres associated with age-related diseases. Lifestyle interventions mitigating telomere shortening are essential for preventing such conditions. This study aimed to examine the effects of two weight loss dietary strategies, based on a moderately high-protein (MHP) diet and a low-fat (LF) diet on TL in i

Telomere length and 4-year changes in cognitive function in an older Mediterranean population at high risk of cardiovascular disease

Background: Cognitive decline, a common process of brain ageing, has been associated with telomere length (TL). Delving into the identification of reliable biomarkers of brain ageing is essential to prevent accelerated cognitive impairment. Methods: We selected 317 non-smoking 'Prevención con Dieta Mediterránea-Plus' (PREDIMED-Plus) participants (mean age, 65.8 ± 5.0 years) with metabolic syndrome

Evaluating the Applicability of a Real-Time Highly Oxygenated Organic Molecule (HOM)-Based Indicator for Ozone Formation Sensitivity at a Boreal Forest Station

Ground-level ozone (O3), formed via complex photochemistry involving nitrogen oxides (NOx) and volatile organic compounds (VOCs), is a critical secondary pollutant and oxidant. Therefore, understanding whether the formation of O3 is NOx- or VOC-limited is essential for effective air quality management. Recently, we demonstrated that the distribution of highly oxygenated organic molecules (HOMs) ca

Concussion in para sport : the first position statement of the Concussion in Para Sport (CIPS) Group

Concussion is a frequent injury in many sports and is also common in para athletes. However, there is a paucity of concussion research related to para sport, and prior International Concussion in Sport (CIS) consensus papers have not substantively addressed this population. To remedy this and to improve concussion care provided to para athletes, the concussion in para sport (CIPS) multidisciplinar

RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma

Background: RORγt is a transcription factor that enables elaboration of Th17-associated cytokines (including IL-17 and IL-22) and is proposed as a pharmacological target for severe asthma. Methods: IL-17 immunohistochemistry was performed in severe asthma bronchial biopsies (specificity confirmed with in situ hybridization). Primary human small airway epithelial cells in air liquid interface and p

Cardiovascular Profile of South African Adults with Low-Level Viremia during Antiretroviral Therapy

Chronic inflammation is an HIV infection feature, contributing to elevated risk of cardiovascular disease among people with HIV, which can be induced by viral replication. A proportion of antiretroviral therapy (ART) recipients fail to achieve viral suppression, despite not meeting criteria for treatment failure, so-called low-level viremia (LLV). We investigated the relationship between LLV and a