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Multigene assays for molecular subtypes and biomarkers can aid management of early invasive breast cancer. Using RNA-sequencing we aimed to develop single-sample predictor (SSP) models for clinical markers, subtypes, and risk of recurrence (ROR). A cohort of 7743 patients was divided into training and test set. We trained SSPs for subtypes and ROR assigned by nearest-centroid (NC) methods and SSPs
OBJECTIVES: Using a nationally-representative, cross-sectional cohort, we examined nutritional markers of undiagnosed type 2 diabetes in adults via machine learning.METHODS: A total of 16429 men and non-pregnant women ≥ 20 years of age were analysed from five consecutive cycles of the National Health and Nutrition Examination Survey. Cohorts from years 2013-2016 (n = 6673) was used for external va
The subject matter of the thesis is the comprehensive - legal and multidisciplinary - analysis of the terms 'peoples' and 'minorities' in international law. The argument of the author proceeds in four parts: the Problematique which deals with the 'minority challenge' and the international normative response to that challenge; the Critique, criticizing the basic underlying assumptions of the discou
Uppsatsen undersöker huvudsakligen gällande rätt beträffande tillåtligheten av skriftliga vittnesattester i svenska kommersiella skiljeförfaranden. Undersökningen är inriktad på förutsättningarna för skiljenämnden att tillåta, påbjuda eller förbjuda användandet av skriftliga vittnesattester när en av parterna bestrider att de ska användas. Undersökningens syfte är således att genom den rättsdogmat
I Sverige måste man som utgångspunkt samtycka till all hälso- och sjukvård. Det förutsätter att man har beslutsförmåga vilket för patienter med demens-sjukdom inte alltid är fallet. Tydliga regler för hur vård ska ges till patienter som inte har förmågan att samtycka och bestämma över sin vård saknas i Sverige. Denna framställning uppehåller sig kring denna problematik. Uppsatsen syfte är att undIn Sweden, consent is required for all health care. This requires the ability to make decisions, which is not always the case for patients with dementia. Clear rules on how care should be provided to patients who do not have the capacity to consent and decide on their care are lacking in Sweden. This presentation focuses on this problem. The aim of the paper is to examine the right to health of p
Arbetsdomstolen har i flera fall, i förhållande till kollektivavtalade avvikelser från semidispositiv rätt, tillämpat en princip om att sådana kollektivavtal är ogiltiga om de innebär en otillbörlig urholkning av arbetstagarnas lagstadgade rättigheter eftersom det strider mot lagens grunder. Med anledning av rättsfal-let AD 2023 nr 33, där den kollektivavtalade anställningsformen SLUV (viss-tid ”sThe Swedish Labour Court (Arbetsdomstolen) has, in several cases concern-ing deviations from semi-dispositive law as stipulated in collective agree-ments, applied a principle that such collective agreements are invalid if they result in an undue erosion of employees' statutory rights because it contra-venes the fundamental principles of the law. In light of the case AD 2023 no. 33, where the c
Every year, millions of people are internally displaced as a result of disasters and the adverse effects of climate change. Considering that climate change acts as a “threat multiplier”, thus, posing a serious risk to the fundamental rights, such as the rights to life, health, food, an adequate standard of living of individuals and communities worldwide, it is expected that the magnitude of this i
För närmare åtta år sedan, 2011, ändrade Högsta domstolen (HD) sin tidigare praxis avseende tolkningen av 1 kap. 2 § andra stycket brottsbalken (BrB) – alltså det lagrum som reglerar uppsåt vid självförvållat rus. Den nya tolkningen innebar att uppsåt i dessa fall skulle behandlas enligt vanliga regler om uppsåt. Det är således inte längre fråga om att fingera uppsåt, inte ens i någon mån. SuzanneNearly eight years ago, in 2011, the supreme court of Sweden changed its previously established practice regarding the interpretation of Chapter 1, art. 2, 2nd paragraph of the Penal Code1 where intent and self-induced intoxication are addressed. A consequence of the new interpretation was that criminal intent in such cases of intoxication should instead be tried as intent in general and thus ther
Förhållandet mellan dataskyddsförordningen (GDPR) och artikel 8 i Euro-peiska konventionen om de mänskliga rättigheterna (EKMR) utgör huvud-fokus för denna studie. I takt med att personuppgifter spelar en alltmer cen-tral roll i det moderna samhället blir de rättsliga standarderna för skydd av privatlivet viktigare, både i nationella och internationella sammanhang. GDPR betraktas ofta som ett instThe relationship between the General Data Protection Regulation (GDPR) and article 8 of the European Convention on Human Rights (ECHR) is the main focus of this study. As personal data plays an increasingly central role in modern society, the legal standards for privacy protection become more important, both in national and international contexts. The GDPR is often viewed as a high-standard data p
We are entering an era that some describe as the Fourth Industrial Revolution, triggered by the development of artificial intelligence. Considering the impact that developments in artificial intelligence have had, and will continue to have on society, discussions have arisen on the implications for the patent system. The DABUS case highlights that the inventorship status under European patent law
SAMMANFATTNING Syfte: Syftet med denna studie har varit att granska den litteratur som finns inom ämnet hälsofrämjande arbete i organisationer. Vår avsikt var att granska aktuella artiklar och inlägg i den pågående debatten. Design/metod/angripningssätt: Vi har studerat 62 olika källor för att skapa oss en trovärdig överblick av ämnet hälsofrämjande arbete. Dessa har granskats, generaliserats och
Wet room - demands and rules This paper explains how the legislative system is built concerning wet rooms within the construction industry. Legislation is developed by all involved authorities. The state has created laws and regulations through parliament and government. These laws are used as a foundation for Boverket, who has produced BBR, which specifies the minimum requirements for the propert
Stare decisis is the doctrine whereby judges and courts rely on previous cases to support a current decision. This doctrine has been associated with legal reasoning and with positive outcomes such as continuity, stability and predictability of the legal system . In the EU, the ECJ does not strictly adhere to this doctrine, unlike common-law systems. However, this court seldom depart from its case
När bestämmelserna om unionsmedborgarskap introducerades i Fördraget om Europeiska Unionen 1992 var det få som trodde att de skulle få någon betydelse bortom det symboliska. Genom en omfattande serie rättsfall har EU-domstolen utvecklat rättigheter kopplade till unionsmedborgarskap, där uppehållsrätten och rätten att fritt vistas inom Unionen är de centrala rättigheterna. Dessa rättigheter aktiverWhen the legal concept of Union citizenship was first introduced in the Treaty of the European Union in 1992, few thought that the provisions would gain any notable significance beyond the symbolical. But through its case law, the European Court of Justice (ECJ) has gradually developed a body of rights connected to the status of Union citizenship, with the rights of residence and free movement, an
Frågan huruvida det kan medges avdrag för ingående mervärdesskatt på råd-givningstjänster som hänför sig till planering av avyttring av dotterbolagsak-tier har var prövats ett flertal gånger. Uppfattningen i tidigare rättspraxis har varit att anskaffning av rådgivningstjänster i samband med aktieavyttringar inte kan medges avdragsrätt. Detta grundar sig i att kostnaderna för rådgiv-ningstjänsternaThe question of whether input VAT on advisory services relating to the plan-ning of the disposal of shares in a subsidiary can be deducted has been exam-ined several times. The view of previous case law has been that the acquisition of advisory services in connection with share disposals cannot be deducted. This is based on the fact that the costs of advisory services are too closely linked to sha
Abstract This essay will examine if there is a possibility that the Millennium Development Goal number 3 (MDG 3) can be achieved by year 2015 in Bangladesh. Therefore, an examination will be performed of the report The Millennium Development Goals, Bangladesh Progress Report 2011. Focus will be on MDG 3 which aims on promoting gender equality and women’s empowerment for instance in Bangladesh. In
This study is concerned with the collaboration between museums and amateur performers of historical reenactment and living history i Sweden. Historical reenactment were examined as a cultural phenomenon and as a potential way of bringing new volunteers and partners to the museum. Historical reenactment is part of a more traditional museology which emphasize the knowledge of museum collections and
