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Yacon (Smallanthus sonchifolius) is a native Andean plant rich in phenolic compounds, and its effects on dysmetabolism and cardiomyopathy in diabetic rats was evaluated. The rats (10/group) were allocated as follows: C, controls; C + Y, controls treated with Yacon leaf extract (YLE); DM, diabetic controls; and DM + Y, diabetic rats treated with YLE. Type 1 diabetes (T1DM) was induced by the admini

Introduction: The PRODIGE 7-trial investigated the additional value of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to cytoreductive surgery (CRS) for patients with colorectal peritoneal metastases (CPM). The results of PRODIGE 7 were presented at the 2018 ASCO meeting showing that 30 min oxaliplatin-based HIPEC did not improve overall survival. The current study investigated the impact of PR

As a way to understand vegetation changes, trend analysis on NDVI (normalized difference vegetation index) time series data have been widely performed at regional to global scales. However, most long-term NDVI datasets are based upon multiple sensor systems and unsuccessful corrections related to sensor shifts potentially introduce substantial uncertainties and artifacts in the analysis of trends.

Background: Widespread implementation of Alzheimer's disease biomarkers in routine clinical practice requires the establishment of standard operating procedures for pre-analytical handling of cerebrospinal fluid (CSF). Methods: Here, CSF collection and storage protocols were optimized for measurements of β-amyloid (Aβ). We investigated the effects of (1) storage temperature, (2) storage time, (3)

BACKGROUND: While experimental data suggest that selective intracoronary hypothermia decreases infarct size, studies in patients with ST-elevation myocardial infarction (STEMI) are lacking. AIMS: We investigated the efficacy of selective intracoronary hypothermia during primary percutaneous coronary intervention (PCI) to decrease infarct size in patients with STEMI. METHODS: In this multicentre ra

Many exemplary projects have demonstrated that Nature-based Solutions (NBS) can contribute to climate change adaptation, but now the challenge is to scale up their use. Setting realistic policy goals requires knowing the amount of different NBS types that can fit in the urban space and the benefits that can be expected. This research aims to assess the potential for a full-scale implementation of

BACKGROUND: Long QT syndrome (LQTS) is caused by the abnormal function of ion channels, which may also affect atrial electrophysiology and be associated with the risk of atrial fibrillation (AF). However, large-scale studies of AF risk among patients with LQTS and its relation to LQTS manifestations are lacking. We aimed to assess the risk of AF and its relationship to the LQTS genotype and the lo

Syftet med denna sammanläggningsavhandling är att belysa de etiska, juridiska och politiska konsekvenserna av olika försök att hantera lidande hos djur orsakat av industriell djurproduktion. På basis av kvalitativa studier utförda i Danmark undersöker avhandlingen hur skötseln av lantbruksdjur förhandlas inom olika sociala domäner. För detta ändamål använder avhandlingen rättssociologiska och tvärThis compilation thesis aims to develop an understanding of the ethical, legal and political implications associated with different strategies to address the suffering of animals caused by industrialised agriculture. Based on qualitative analysis conducted in Denmark, the research explores how ethical commitment to the situation of farmed animals is negotiated across different domains. The thesis

Mutation-bearing peptide ligands from mutated nucleophosmin-1 (NPM1) protein have been empirically found to be presented by HLA class I in acute myeloid leukemia (AML). We hypothesized that HLA genotype may impact allogeneic hematopoietic stem cell transplantation (allo-HCT) outcomes in NPM1-mutated AML owing to differences in antigen presentation. We evaluated the effect of the variable of predic

We present a method for human brain fixation based on simultaneous perfusion of 4% paraformaldehyde through carotids after a flush with saline. The left carotid cannula is used to perfuse the body with 10% formalin, to allow further use of the body for anatomical research or teaching. The aim of our method is to develop a vascular fixation protocol for the human brain, by adapting protocols that a

Groundwater is a crucial source of water supply in drought conditions, and an auxiliary water source in wet seasons. Due to its increasing importance in view of climate change, predicting groundwater level (GWL) needs to be improved to enhance management. We used adaptive neuro-fuzzy inference systems (ANFIS) to predict the GWL of the Urmia aquifer in northwestern Iran under various input scenario

This master’s thesis examines 21 master’s theses written in Library and Information Science in Sweden between the years 2010 and 2013. The master’s theses are written in Lund, Borås and Uppsala and all of them have literature and/or reading as subject matters. The aim of the thesis is to investigate how master’s theses in our time handle the question of reading and literature as a subject matter i

Detta arbete behandlar frågan om vad det inom migrationsrätten gällande beviskravet sannolikt innebär ur ett sannolikhetsteoretiskt perspektiv vid tillämpning framför allt av utlänningslagen (2005:716) 4 kap. 1 §. Utvald del av denna paragraf tolkas och delas upp i delteman. Utifrån dessa delteman undersöks vad som måste uppnå vilken sannolikhet och hur sannolikheten för olika delteman påverkar saThis is a thesis on the issue of what the evidentiary requirement within the field of migration law, probable, implies, from a probabilistic point of view, especially when applying the 1st article of the 4th chapter in the Swedish Aliens Act (2005:716), about refugee status. A selected part of this article is interpreted and divided into sub-themes of proof (these could also be referred to as prop

This thesis set the goal to contribute to the fields of diaspora studies and cultural studies from a media and communication studies angle by addressing the blank spots ‘white minorities’ and book use. White diasporas are nearly invisible within academia and very often ‘under the radar’ in society as well. Books are underresearched within media studies in favour of other media. On the other hand,

Economic inequality is growing rapidly worldwide. Despite research showing that higher inequality within a society corresponds with a higher rate of public health and social problems, there exist little organized resistance against the neo-liberal economic policies that allow the super-rich to pull away from the rest of the population. Even though the causes of poverty cannot be separated from the

The aim of this thesis is to shed some light on the emerging mainstream news discourses connected to marijuana’s legalization in parts of the United States by asking who is most involved in these discourses, what connections involvement may have to social status and social factors, most significantly gender, as well as what a few discursive themes in marijuana-related coverage might be, and what f

Populärvetenskaplig sammanfattning: Fjällen i Kebnekaiseområdet är bland de högsta i Sverige (runt 2000 m.ö.h.) och de är uppbyggda av en mängd olika bergarter. Dessa bergarter bildades ursprungligen långt väster om våran fjällkedja på olika platser och fördes samman under den så kallade Kaledoniska orogenesen. En orogenes orsakas vanligtvis av att två kontinenter kolliderar med varandra och berThe tectonostratigraphic units in northern Kebnekaise Mountains mainly belong to the Seve Nappe Complex. These rocks were originally formed at the continental margin of Baltica in Late-Proterozoic time and mainly consist of amphibolite, granitic gneisses and metasediments. The metamorphic grade is usually amphibolite facies. The areas investigated in this work, Nallo and Mårma, consist of four di