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PowerPoint Presentation ACS and Open Science David Armstrong Senior Marketing Manager, Institutional Partnerships darmstrong@acs-i.org 1 Our ‘open’ history Open data New Research Data Policy adopted from September 2021 Each ACS journal independently determines the most appropriate level for its community More information available in each journal’s Instructions for Authors Full details at publish.
Human carbonyl reductase 1 (CBR1), that is one of the enzymes responsible for the reduced efficiency of treatments by the antineoplastic agents anthracyclines, was functionally expressed in Saccharomyces cerevisiae. CBR1 was purified and kinetically characterised using daunorubicin as substrate. CBR1-catalysed reduction of daunorubicin followed an apparent Michaelis-Menten kinetics with K-M = 85.2
Enzymes of the xanthine oxidase family are among the best characterized mononuclear molybdenum enzymes. Open questions about their mechanism of transfer of an oxygen atom to the substrate remain. The enzymes share a molybdenum cofactor (Moco) with the metal ion binding a molybdopterin (MPT) molecule via its dithiolene function and terminal sulfur and oxygen groups. For xanthine dehydrogenase (XDH)
We have studied the convergence of QM/MM calculations with respect to the size of the QM system. We study a proton transfer between a first-sphere cysteine ligand and a second-sphere histidine group in [Ni,Fe] hydrogenase and use a 446-atom model of the protein, treated purely with QM methods as a reference. We have tested 12 different ways to redistribute charges close to the junctions (to avoid
Popular Abstract in English Proteins are a big biological molecules that help cells to function. Proteins play important roles in all vital processes of the living cell, transporting molecules, speeding up chemical reactions, supporting structure of other proteins and the cell, helping the cell to move. Various disease-causing agents (e.g. bacteria and viruses) are constant threat to us. It is thMost drugs act on biomacromolecules. The Cost of developing new drugs is very high. A method to accurately predict binding affinities would be very useful. We have studied molecular mechanics with generalised Born and surface--area solvation (MM/GBSA) and alchemical free energy perturbation methods (FEP) for use in calculations of ligand binding energies. For the MM/GBSA method we have tested: Ca
Remediation of contaminated sites may cause adverse negative effects like usage of non-renewable resources, high monetary cost, air emissions and an increased risk of accidents. Therefore, interest in sustainable remediation has increased in recent years. The aim with sustainable remediation is to integrate a holistic perspective on remedial projects and find the alternative that is considered bes
In recent years, hydrogels have been demonstrated as simple and cheap additives to improve the optical properties and material stability of organometal halide perovskites (OHPs), with most research centered on the use of hydrophilic, petrochemical-derived polymers. Here, we investigate the role of a peptide hydrogel in passivating defect sites and improving the stability of methylammonium lead iod
Climate change and human impact play a huge role in the sustainability and development of ecosystems and the services they offer to societies over temporal and spatial scales. Fossil pollen-based estimates provide unique information on past land cover change, but to date there are not many methods able to create spatially continuous maps and have a fine scale of land cover changes inferred from po
Proton Beam Therapy (PBT) is an increasingly utilised modality for treating tumours by utilising the physical properties of accelerated proton beams. This review explores the development of PBT, its dosimetric advantages over conventional x-ray-based radiotherapy, and the rationale behind its use in paediatric oncology whilst simultaneously considering the various challenges associated with its de
Research Strategy for Lund University 2023-2026 RESEARCH STRATEGY | 2023–2026 Research Strategy LUND UNIVERSITY | 2023–2026 RESEARCH STRATEGY | 2023–2026 3 RESEARCH STRATEGY | 2023–2026 L und University is a university rich in tradition with a broad range of subjects, excellent research and top- class research infrastructure. At a time of challenges that require global cooperation, and when compet
Affilierad forskare Kontaktinformation E-post: monika [dot] lindbekk [at] soclaw [dot] lu [dot] seOrganisation Rättssociologiska institutionen Hämtställe: 31 WebbplatsMonika Lindbekks profil i Lunds universitets forskningsportalAndra roller Postdoc Rättssociologiska institutionenForskningsområdenRättskulturer och komparativ rättGenusBeslutsfattande i domstolarPågående forskningMonika Lindbekks for
https://www.soclaw.lu.se/monika-lindbekk - 2026-07-06
EMP IMEP15 - ESA Environmental Systems and the Anthropocene Mandatory readingMandatory readingTextbookEnvironment, 10th EditionAuthors: David M. Hassenzahl; Mary Catherine Hager; Nancy Y. Gift; Linda R. Berg; Peter H. RavenChapter 1: Introducing Environmental Science and SustainabilityChapter 3: Ecosystems and EnergyChapter 4: Ecosystems and the Physical EnvironmentChapter 5: Ecosystems and Living
https://www.iiiee.lu.se/masters-programme-environmental-management-and-policy-emp/literature-lists - 2026-07-05
Microsoft Word - Lunds universitets exportkontrollprogram_STYR2020_2073_tillg Sida 1 av 22 Rektor BESLUT Diarienummer STYR 2020/2073 Datum 2021-10-21 Lunds universitets exportkontrollprogram – efterlevnadsprogram för produkter med dubbla användningsområden Fastställt av rektor 2021-10-21. Postadress Box 117 Besöksadress Sandgatan 5 Telefon 046-222 69 29, 046-222 00 00 E-post robert.collin@bygg.lu.
Non-covalently molecularly imprinted polymers (MIPs) for beta(2)-amino acids were prepared for the first time. N-(2-chlorobenzyloxycarbonyl)-(R)-beta(2)-homophenylalanine (N-2-ClZ-(R)-beta(2)-HPhe)was imprinted with methacrylic acid (MAA) and/or 4-vinylpyridine (4-VPy) as the functional monomers, with ethylene glycol dimethacrylate ( EDMA) as the cross-linker. The MIPs made with different ratios o
Digital elevation models (DEMs) can be captured and analysed by various methods. Elevation capturing with RTK-GPS and airborne laser scanning is presented and evaluated in terms of height accuracy of raw data and interpolated DEMs for study sites in Sweden and Germany. Applications for precision agriculture are based on the connection of land surface and the movement of water in the landscape. Thr
Both spring temperature and date of the first Starling Sturnus vulgaris egg were highly correlated between different study sites and weather stations in the southern half of Sweden. In southern Sweden, but not in northern Sweden, onset of breeding correlated strongly with spring temperature, particularly during the last ten days of April, the period that happens to coincide with the start of breed
Abstract. This study presents a comprehensive assessment of the meteorological conditions and atmospheric flow during the Lagrangian-type "Hill Cap Cloud Thuringia 2010" experiment (HCCT-2010), which was performed in September and October 2010 at Mt. Schmücke in the Thuringian Forest, Germany and which used observations at three measurement sites (upwind, in-cloud, and downwind) to study physical
This study sheds light upon how memes about rioting in present-day Belfast are read by their audiences. As such, it answers to a distinct research gap in the meme studies literature, which has mostly shied away from in-depth engagements with audiences, favouring instead the intertwined concepts ‘imagined audience’ and the ideological ‘directionality’ of memes. Drawing on semi-structured interviews
MARS MÅNAD nr.3 MÅNADSBREV FRÅN DET MODEVETENSKAPLIGA STUDIERÅDET Hej kära läsare! Hoppas att ni har haft en underbar vår än så länge och att ni njuter när solen väl tittar fram. Just nu är vi i det Modevetenskapliga Studie- rådet mitt i en tentaperiod och har därför valt att ge ut ett lite mindre månadsbrev än vanligt. I en virvelvind av vårtrötthet och deadlines måste jag erkänna att inspira- ti
https://www.kultur.lu.se/fileadmin/user_upload/kultur/Utbildning/Mode_maanadsbrev/Maanadsbrev_Mars_2023.pdf - 2026-07-06
Ground level ozone [ozone] is considered a harmful air pollutant but there is a knowledge gap regarding its long term health effects. The main aim of this study is to develop local Land Use Regression [LUR] models that can be used to study long term health effects of ozone. The specific aim is to develop spatial LUR models for two Swedish cities, Umea and Malmo, as well as a temporal model for Mal
