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Enzymatic Reduction of Ketones

Methods have been studied for the production of chiral alcohols, which are of importance in organic synthesis of pharmaceuticals, agro-chemicals and fragrances, etc., through the enzymatic or microbial reduction of ketones. Classical reaction engineering was combined with genetic engineering to improve the production of chiral alcohols and kinetic resolution of racemic ketones with high enantiomer

Extensive central nervous system involvement in Merkel cell carcinoma : a case report and review of the literature

INTRODUCTION: Merkel cell carcinoma is a rare malignant cutaneous neoplasm that is locally invasive and frequently metastasizes to lymph nodes, liver, lungs, bone and brain. The incidence of Merkel cell carcinoma has increased in the past three decades.CASE PRESENTATION: A 65-year-old Caucasian man presented with a sudden onset of severe headache and a three-month history of balance disturbance. M

Geophysical investigation of arural water point installation program in Nampula province, Mozambique

There are many projects in Mozambique for poverty reduction. One of these projects is funded by Millennium Challenge Account (MCA) and is aimed to install a total of 600 rural water points in the province of Nampula and Cabo Delgado in crystalline rock zone. Each water point consists of a drilled well, a water pump and a communal washing basin. Vertical Electrical Sounding (VES) was used for asses

Synthesis of naproxen-imprinted polymer using Pickering emulsion polymerization

For the last decades, molecular imprinting is developing intensively, especially in the case of the application of new imprinting techniques. In this work, for the first time, a Pickering emulsion polymerization was used to synthesize the S-naproxen-imprinted polymer spheres following a noncovalent protocol. To enhance the knowledge about imprinting process using mentioned technique, thorough anal

Antarctic glacial history since the Last Glacial Maximum: an overview of the record on land

This overview examines available circum-Antarctic glacial history archives on land, related to developments after the Last Glacial Maximum (LGM). It considers the glacial-stratigraphic and morphologic records and also biostratigraphical information from moss banks, lake sediments and penguin rookeries, with some reference to relevant glacial marine records. It is concluded that Holocene environmen

Poly(arylene piperidinium) hydroxide ion exchange membranes: synthesis, alkaline stability and conductivity

A series of poly(arylene piperidinium)s (PAPipQs) devoid of any alkali-sensitive aryl ether bonds or benzylic sites are prepared and studied as anion exchange membranes (AEMs) for alkaline fuel cells. First, the excellent alkaline stability of the model compound 4,4-diarylpiperidinium is confirmed. Medium molecular weight poly(arylene piperidine)s are then synthesized in polycondensations of N-met

Improving the Performance of OTDOA based Positioning in NB-IoT Systems

In this paper, we consider positioning with observed-time-difference-of-arrival (OTDOA) for a device deployed in long-term-evolution (LTE) based narrow-band Internet-of-things (NB-IoT) systems. We propose an iterative expectation- maximization based successive interference cancellation (EM-SIC) algorithm to jointly consider estimations of residual frequency- offset (FO), fading-channel taps and ti

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay

Lysosomal membrane permeabilization (LMP) contributes to tissue involution, degenerative diseases, and cancer therapy. Its investigation has, however, been hindered by the lack of sensitive methods. Here, we characterize and validate the detection of galectin puncta at leaky lysosomes as a highly sensitive and easily manageable assay for LMP. LGALS1/galectin-1 and LGALS3/ galectin-3 are best suite

The Ordovician System of South Africa : a review

Outcrops of the Ordovician System in South Africa are extensive; they cover significant portions of the Northern, Western and Eastern Cape provinces as part of the Cape Fold Belt as well as the KwaZulu-Natal Province as supracrustal cover overlying the Natal sector of the Paleoproterozoic Namaqua-Natal metamorphic province. Within the Cape Fold Belt, Ordovician rocks of the Table Mountain Group (P

Oxidation of 5-hydroxymethylfurfural with a novel aryl alcohol oxidase from Mycobacterium sp. MS1601

Bio-based 5-hydroxymethylfurfural (HMF) serves as an important platform for several chemicals, among which 2,5-furan dicarboxylic acid (FDCA) has attracted considerable interest as a monomer for the production of polyethylene furanoate (PEF), a potential alternative for fossil-based polyethylene terephthalate (PET). This study is based on the HMF oxidizing activity shown by Mycobacterium sp. MS 16

Ett liv i trängsel

The aim of this paper was to analyse how stakeholders such as municipalities and tourism operators at small-scale destinations strategically work to handle issues regarding carrying capacity in order to protect the social sustainability. The paper examines the world heritage site Cinque Terre in Italy, which has experienced a major change in tourist flows during the last decade. The comprising fiv

Translating the City : Identity and Mobility in a Mediated City - A Case Study of Recent Turkish Immigrants in Berlin,Germany

The aim of this study is to explore the relationship of recent Turkish immigrants with the city of Berlin through the lens of media and communication, and to identify the identity dynamics in this relationship. The relationship with, and links of immigrants to their countries of origin is a common subject in diaspora studies, human geography, and media and communication studies. However, more rese

Jonas Helgertz

Vicerektor forskning, Docent Kontaktinformation E-post: jonas [dot] helgertz [at] ekh [dot] lu [dot] se Telefon: +46 46 222 36 66Organisation Ekonomisk-historiska institutionen Besöksadress: Scheelevägen 15 B, Lund Rumsnummer: Alfa 1:2008 Hämtställe: 10 WebbplatsJonas Helgertz profil i Lunds universitets forskningsportalAndra roller Universitetslektor Ekonomisk demografi Professor Ekonomisk-histor

https://www.ehl.lu.se/jonas-helgertz - 2026-04-30

Simulation of periodic counter-current chromatography purification of monoclonal antibodies with column degradation

Uppreningsprocessen av monoklonala antikroppar (mAbs) är dyr, speciellt det kromatografisteg där antikropparna separeras från andra protein och celler i lösningen från tidigare steg i processen. Antikropparna separeras från lösningen med hjälp av affinitetskromatografi, där det endast är antikropparna som interagerar med innehåller i kolonnen och stannar kvar, medan resten passerar obehindrat. AntThe purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column

Ebsco-new-databases-ahmed-kafafi

Välkomna till EBSCO Roadshow 2024 / Welcome to EBSCO Roadshow 2024 | www.ebsco.com |1 Account Executive Ahmed Kafafi Region Sales Manager, Mats Påhlsson | www.ebsco.com |2 Agenda • MEDLINE Ultimate • CINAHL Ultimate • LitBase • RIPM • Questions | www.ebsco.com |3 MEDLINE Ultimate | www.ebsco.com |4 MEDLINE Ultimate provides active full text for 46% of MEDLINE’s currently indexed journals • Active

https://www.ub.lu.se/sites/ub.lu.se/files/2024-05/ebsco-new-databases-ahmed-kafafi.pdf - 2026-05-01

Towards modeling and improving human-centered code review

Tool-based code review has been an established software engineering practice for at least a decade. However, while software development environments have improved significantly during this time with advanced features for code comprehension, refactoring, and AI support, code review tools have remained more static and are still centered around a two-way textual diff view with features similar to whe

Machine learning evaluation for identification of M-proteins in human serum

Serum electrophoresis (SPEP) is a method used to analyze the distribution of the most important proteins in the blood. The major clinical question is the presence of monoclonal fraction(s) of antibodies (M-protein/paraprotein), which is essential for the diagnosis and follow-up of hematological diseases, such as multiple myeloma. Recent studies have shown that machine learning can be used to asses

Resource Management in Distributed Camera Systems

The aim of this work is to investigate different methods to solve the problem of allocating the correct amount of resources (network bandwidth and storage space) to video camera systems. Here we explore the intersection between two research areas: automatic control and game theory. Camera systems are a good example of the emergence of the Internet of Things (IoT) and its impact on our daily lives

Global Cell-ID Positioning Using Artificial Neural Networks

Den som har använt GPS under en längre tid med en äldre telefon eller en smart klocka har antagligen märkt att batteriet snabbt tar slut. GPS har dessutom sämre precision om du är inomhus eller i en större stad med höga byggnader. I detta examensarbete så undersöks en alternativ teknik för utomhuspositionering som är mer batterivänlig än GPS. GPS har länge dominerat inom positionering på grund avFor many years, outdoor localization has been dominated by Global Positioning System (GPS) and other GNSS-based methods. While GPS provides global coverage and usually high accuracy, it has its limitations. GPS has lower accuracy in areas with many obstructions, such as buildings or trees, and is power consuming compared to other localization methods. Therefore, GPS may not be the best localizatio

The Number of the Beast : Reducing Additions in Fast Matrix Multiplication Algorithms for Dimensions up to 666

While a naive algorithm for multiplying two 2 × 2 matrices requires eight multiplications and four additions, Strassen showed how to compute the same matrix product using seven multiplications and 18 additions. Winograd reduced the number of additions to 15, which was assumed to be optimal. However, by introducing a change of basis, Karstadt and Schwartz showed how to lower the number of additions