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The rationale for thrombolysis, the most promising pharmacological approach in acute ischaemic stroke, is centred on the principal cause of most ischaemic strokes: the thrombus that occludes the cerebral artery, and renders part of the brain ischaemic. The occluding thrombus is bound together within fibrin. Fibrinolysis acts by activation of plasminogen to plasmin; plasmin splits fibrinogen and fi
This thesis addresses the impact of glaucoma on the patients’ vision from both a measurement based and a functionally based perspective. The risk of visual disability is probably the most important question for a newly diagnosed glaucoma patient and maintaining vision-related quality of life (VRQOL) has become the ultimate goal of glaucoma treatment. The objectives of the present thesis were to de
Popular Abstract in Swedish Kroniska ländryggsbesvär är en ekonomisk belastning för sjukvården och samhället i stort, och ger framför allt ett personligt lidande för den drabbade. Nästan alla (75-80 %) kommer att ha åtminstone en episod med ryggbesvär någon gång under sin livstid. Hälften av dessa kommer att ha utstrålande bensmärtor och ofta är besvären ett symtom på ischias (nervrotspåverkan). MRadicular pain is in the majority of cases caused by a disc herniation with a coexisting inflammation. It is characterized by positive neural tension tests, such as the Slump test, and by decreased range of motion (ROM) in the straight leg raising test (SLR) and lumbar flexion (Fingertip-to-floor test[FTF]). This may suggest that improvement in ROM correlates to reduction of self-reported disabili
Det är inte ovanligt att upphandlande myndigheter använder sig av referenser i upphandlingsprocessen. Ett exempel är att den upphandlande myndigheten ställer krav på att anbudsgivarna ska presentera referenser, exempelvis om hur en tjänst likartad den som offereras i upphandlingen tidigare har utförts eller referenser som styrker krav på en viss kompetens. Det är då fråga om referenser i form av kIt is not uncommon for contracting authorities make use of references in the procurement process. One example is that the contracting authority requires that bidders must present credentials, such as how a service similar to that quoted in the contract has been experienced or references proving the requirement for a specific skill. This is then a question of credentials in the form of qualificatio
Surrogatmoderskap har sedan mitten av 1980-talet varit omdiskuterat i Sverige i och med att frågan om assisterad befruktning då uppmärksammades, men än så länge är surrogatmoderskap inte tillåtet i landet. I juni 2015 ska det dock publiceras en statlig utredning vilken ska uttala huruvida en legalisering av arrangemanget borde ske och hur detta i så fall ska regleras. Statens medicinsk-etiska rådEver since the middle of the 1980s when artificial insemination was given attention surrogacy have been much-disputed in Sweden, but so far surrogacy is not legal in the country. However in June 2015 a government investigation will be published which will convey whether or not surrogacy should be legalised and if so how the arrangement should be regulated. Statens medicinsk-etiska råd published a
The maritime transportation of hazardous cargo has created a sometimes intense dispute between the shipping industry and coastal states. The arguments feeding this discussion are the right of innocent passage, claimed by shipping states, and on the other hand, the obligation to protect the environment stressed by coastal states. Two sets of rules, both codified in international law, stand in confl
Populärvetenskaplig sammanfattning: De begravda jordmånsbildningarna vid Sandhammaren och Skanörs ljung, södra Sverige, är lokaliserade inom kustnära dynlandskap som har bildas i response till land-och havsnivåförändringar efter den sista istiden (efter ca. 10 000 år sedan). Jordmånerna är begravda av flygsand och karakteriseras av flera organiska lager med tillhörande urlaknings-och anrikningshorThe palaeosoils at Sandhammaren and Skanörs ljung, southern Sweden, are located within a coastal dune landscape that developed in response to Holocene land/sea changes. These buried soils are characterised by several organic layers including pedological horizons. They were studied for fossil pollen, and soil chemistry (iron, aluminium, manganese, phosphorous, carbon and pH) in order to appreciate
Abstract COPD is a major cause of chronic morbidity and mortality throughout the world. It is a preventable and treatable disease. Smoking is the most commonly encountered risk factor for COPD and the habit now unfortunately starts at earlier ages than before. There is a strong necessity to diagnose COPD in early stages before symptoms present themselves. MRI with hyperpolarized 3He using diffusio
Reinforced concrete is one of the most widely used building materials and if it is properly designed and produced, it is an extremely durable material with a service life up to 100 years. However, under certain environmental conditions the service life of reinforced concrete structures is more limited. Deterioration of concrete structure is in most cases caused by the penetration of aggressive med
Popular Abstract in Swedish Stroke är en sjukdom som främst drabbar äldre och är den största anledningen till att människor får olika slags handikapp såsom förlamning och afasi. Det finns ännu ingen effektiv behandling för att lindra symtom och lidande efter en stroke, förutom rehabilitering, och därför kostar stroke samhället enormt mycket pengar. Befolkningen blir allt äldre, vilket även medför Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. The human fetal brain is one potential source of neural stem cells (NSCs) for cell replacement therapy in neurodegenerative disorders such as stroke. Stroke is
The study of Federalism has attracted scholars of various fields for a long time. Federalism as an instrument of balancing the tension between universalism and particularism has drawn more attention in pluralistic societies. After the end of the cold war era there is a drift in to reaffirmation of ethnic identity as a means of determining the public life of a society, the venture to ethnify federa
Title: Finding optimal logistical hubs for Swedish export - A study of selecting global locations Authors: Cecilia Eskilsson and Fredrik Hansson Tutors: Andreas Norrman, Professor, Department of Industrial Management and Logistics, Faculty of Engineering, Lund University, Oskar Henkow, Lecturer, Department of Business Law, School of Economics and Management, Lund University Henrik Danielsson, He
En aktuell debatt i svensk politik är hushållens växande skulder, framför allt i storstadsområdena. Förslag har lagts fram från Finansinspektionen och Sveriges Riksbank om amorteringskrav, skuldkvotstak och sänkt ränteavdrag. Detta för att hämma en eventuellt fortsatt ökning av hushållens skulder. Den svenska hushållssektorns ökande skuldsättning tillskrivs främst de lägre kostnaderna för bolån soA current topic in Swedish politics is the increasing household debt, particularly in the metropolitan areas. The Swedish Central Bank and the Financial Supervisory Authority have made proposals for several policies, to inhibit a continued growth of the household debt. These policies include introducing amortization requirements, a debt-to-income ratio limit and reduced home mortgage interest dedu
Skattelättnader för högkvalificerad utländsk arbetskraft är ett aktuellt ämne i dagens samhälle, eftersom konkurrensen om viss kompetens är hård på den internationella arbetsmarknaden. Syftet med denna uppsats är att analysera de svenska expertskattereglerna i ljuset av motsvarande danska regler. De frågeställningar som har formulerats för att uppnå syftet är hur expertskattereglerna respektive deIn today’s international labour market, the competition for certain competences and skills is tough. Therefore, tax concessions for highly qualified foreign labour has become an increasingly relevant subject. The purpose of this paper is to analyse the Swedish expert tax law vis-á-vis its Danish equivalent. In order to accomplish this, the thesis seeks to investigate how the tax concessions in Swe
Methane is a potent greenhouse gas that plays a major role in climate change. Significant uncertainty exists in the estimates of emissions from natural methane sources. This uncertainty in data is one of the primary scientific challenges in climate model. Geological seepage considered as the second largest natural source of methane after wetlands and today is recognized as a major contributor to a
Background Supply chains in low margin, high innovation speed industries with strong customers generate a highly competitive environment. The conditions for such environment are continuously changing and put high demands on its actors. FlatFrog is a case company, which was founded in 2007 and develops a unique touch technology targeting a wide range of screens sizes and applications. External capi
Purpose: According to guideline recommendations, chest compressions (CC) during cardiopulmonary resuscitation (CPR) should be performed at a rate of 100 - 120 per minute, with a CC fraction (CCF) of ≥80%. The aim of this work is to explore whether CC quality differs between advanced life support (ALS) and basic life support (BLS) performed by two rescuers. Method: Cardiopulmonary resuscitation was
Aims: This study surveyed individuals and caregivers of children who received teplizumab at stage 2 type 1 diabetes (T1D) to garner real-world experiences and their health outlook for the future following treatment with the first approved disease-modifying immune therapy for delaying the onset of Stage 3 T1D. Materials and Methods: This was a cross-sectional, observational, online survey (conducte
Inom beredskapen mot radiologiska och nukleära olyckor och katastrofer spelar strålningsmätningar en avgörande roll för att ta reda på vad som har hänt och hur farligt det är för människa, djur och natur och på vilket sätt det påverkar miljö och samhällsfunktioner. I Sverige och många andra länder i världen har allmänheten en rättighet att få reda på vad som hänt och vad de utsätts för i ett eventThis thesis describes investigations made on mobile and stationary gammaspectrometry made both under laboratory conditions and in situ. The objective hasbeen to identify and quantify radionuclides in the form of point sources,contamination and widespread deposition in situations where the measurementgeometry is not known beforehand. Both scintillators and semiconductor detectors ofsimilar size wer
Background. In the European Study for Pediatric Ph+ ALL (EsPhALL), a total of 128 patients aged 1 to 18 years diagnosed with ALL and evidence of t(9;22)(q34;q11) received post-Induction Imatinib on top of BFM high risk chemotherapy backbone, either in Good Risk (GR) (after randomization, n=58) or in Poor Risk (PR) (n=70), as defined according to early response to the National induction treatment.
