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BACKGROUND: De novo oligometastatic prostate cancer (omPCa) on prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is a new disease entity and its optimal management remains unknown. OBJECTIVE: To analyze the outcomes of patients treated with cytoreductive radical prostatectomy (cRP) for omPCa on PSMA-PET. DESIGN, SETTING, AND PARTICIPANTS: Overall, 116 patients treated wi

Enligt forskare och praktiker innebär klimatförändringarna särskilda utmaningar för freden. För att förstå vilka dessa utmaningar är och hur man ska hantera dem måste man ta hänsyn till kön, eftersom både erfarenheter av och processer för fred, samt drivkrafter bakom klimatförändringar är könsbundna. Exempelvis kan kvinnor och män uppleva förhållandena efter en vapenvila på olika sätt, eller så kaScholars and practitioners argue that climate change poses particular challenges for peace. In order to understand what these challenges are and how to tackle them necessitates attention to gender, since experiences and processes of peace are gendered, as are experiences and drivers of climate change. For instance, women and men may experience conditions after a ceasefire differently, or climate h

IMPORTANCE: Prostate-specific antigen (PSA) screening has potential to reduce prostate cancer mortality but frequently detects prostate cancer that is not clinically important.OBJECTIVE: To describe rates of low-grade (grade group 1) and high-grade (grade groups 2-5) prostate cancer identified among men invited to participate in a prostate cancer screening protocol consisting of a PSA test, a 4-ka

Introduction: The impact of exposure to endemic infections on basal immunity and susceptibility to HIV-1 acquisition remains uncertain. We hypothesized that exposure to infections such as cytomegalovirus (CMV), malaria and sexually transmitted infections (STIs) in high-risk individuals may modulate immunity and subsequently increase susceptibility to HIV-1 acquisition. Methods: A case-control stud

Background: Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) using magnitude inversion recovery (IR) or phase sensitive inversion recovery (PSIR) has become clinical standard for assessment of myocardial infarction (MI). However, there is no clinical standard for quantification of MI even though multiple methods have been proposed. Simple thresholds have yielded varying re

Background: The risk of sustaining a graft rupture after anterior cruciate ligament reconstruction (ACLR) is high. Contributing risk factors are, however, still not clearly identified. Objective: The aim of this systematic review was to identify and quantify risk factors for graft rupture after ACLR. Methods: A systematic review with meta-analysis (PROSPERO CRD42020140129) based on PRISMA guidelin

This paper revises the design process for closed-loop combustion control based on in-cycle feedback. Methods for the necessary observers, detectors and virtual sensors are also discussed. The control problem tackles the indicated efficiency optimization, following two approaches, direct and indirect optimization. The argumentation provides a comprehensive overview on how to specify and integrate d

Importance: Recent studies have questioned the presumed low-risk status of patients with asymptomatic nonsevere aortic stenosis (AS). Whether annual N-terminal pro-brain natriuretic peptide (NT-proBNP) measurements are useful for risk assessment is unknown. Objective: To assess the association of annual NT-proBNP measurements with clinical outcomes in patients with nonsevere AS. Design, Setting, a

Objective. To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome (pSS). Methods. By January 2021, the participant centres had included 12,753 patients from 25 countries that fulfilled the 2002/2016 classification criteria for pSS. The age at diagn

Background: Healthy lifestyles are inversely associated with the risk of noncommunicable diseases, which are leading causes of death. However, few studies have used longitudinal data to assess the impact of changing lifestyle behaviours on all-cause and cancer mortality. Methods: Within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, lifestyle profiles of 308,497 ca

BACKGROUND: Patients on dialysis who have an acute myocardial infarction (AMI) have an exceedingly poor prognosis, but it is unknown to what extent guideline-recommended interventions and treatments are used and to which benefit. We aimed to assess temporal changes in the use of treatments and survival rates in dialysis patients with an AMI. METHODS AND RESULTS: All consecutive AMI cases from 1996

Objectives Registries have been highlighted as means to improve quality of care. Here, we describe temporal trends in risk factors, lifestyle and preventive medication for patients after myocardial infarction (MI) registered in the quality registry Swedish Web-system for Enhancement and Development of Evidence-based care in Heart disease Evaluated According to Recommended Therapies (SWEDEHEART). D

BackgroundTennis is a multidirectional high-intensity intermittent sport for male and female individuals played across multiple surfaces. Although several studies have attempted to characterise the physical demands of tennis, a meta-analysis is still lacking.ObjectiveWe aimed to describe and synthesise the physical demands of tennis across the different court surfaces, performance levels and sexes

Professorsinstallation LUNDS UNIVERSITET | AULAN | 14 OKTOBER 2016 KL 16.00 Denna broschyr finns på installandis institutioner och kan också beställas från sektionen Kommunikation, tel 046-222 70 10, e-post info@kommunikation.lu.se. Broschyren finns även på www.lu.se/om-universitetet/akademiska-hogtider/professorsinstallationer Produktion Sektionen Kommunikation och Media-Tryck, Lunds universitet

https://www.huntington-research.lu.se/sites/huntington-research.lu.se/files/broschyr-professorsinstallation-lunds-universitet-14okt2016.pdf - 2026-05-24

Popular Abstract in Swedish Stroke är en sjukdom som främst drabbar äldre och är den största anledningen till att människor får olika slags handikapp såsom förlamning och afasi. Det finns ännu ingen effektiv behandling för att lindra symtom och lidande efter en stroke, förutom rehabilitering, och därför kostar stroke samhället enormt mycket pengar. Befolkningen blir allt äldre, vilket även medför Cell replacement by neural transplantation can, in animal models of neurodegenerative diseases, reconstruct damaged brain circuitry. In the clinical situation, the graft material used for cell therapy must, most likely, be of human origin. The human fetal brain is one potential source of neural stem cells (NSCs) for cell replacement therapy in neurodegenerative disorders such as stroke. Stroke is

Background: Previous literature indicate retinal hyperspectral imaging as a non-invasive method with the potential for identifying amyloid-beta (Aβ) protein deposits. Current diagnostic methods, such as cerebrospinal fluid analysis or positron emission tomography, are costly, invasive, and non-scalable. Hyperspectral imaging offers a potentially accessible alternative for early detection of Alzhei

LIV U tom jordiskt Syntetisk A rtificiellt Jessica A bbott & Erik Persson (red.) LIV Utomjordiskt Syntet iskt Art i f ic ie l l t Jessica Abbott & Erik Persson (red.) Pufendorfinstitutet/Pufendorf Institute for Advanced Studies Liv är ett centralt begrepp inom många forskningsområden, exempelvis inom biologi, astrobiologi, kemi och medicin, såväl som inom juridik, teologi och filosofi. Liv är ocks

https://www.pi.lu.se/sites/pi.lu.se/files/liv.pdf - 2026-05-24

Skattelättnader för högkvalificerad utländsk arbetskraft är ett aktuellt ämne i dagens samhälle, eftersom konkurrensen om viss kompetens är hård på den internationella arbetsmarknaden. Syftet med denna uppsats är att analysera de svenska expertskattereglerna i ljuset av motsvarande danska regler. De frågeställningar som har formulerats för att uppnå syftet är hur expertskattereglerna respektive deIn today’s international labour market, the competition for certain competences and skills is tough. Therefore, tax concessions for highly qualified foreign labour has become an increasingly relevant subject. The purpose of this paper is to analyse the Swedish expert tax law vis-á-vis its Danish equivalent. In order to accomplish this, the thesis seeks to investigate how the tax concessions in Swe

Bevisvärdering av barns och vuxnas utsagor har länge varit ett omdiskuterat ämne där rättssäkerheten i domstolens fria bevisvärdering har ifrågasatts. I våldtäktsmål är det vanligt att stödbevisning saknas och att ord står mot ord. Hela åtalet tvingas då bygga på målsägandens utsaga, men hur duktig är egentligen domaren på att avgöra huruvida en utsaga är sann eller falsk? Har domaren den kunskap Evaluation of evidence of children's and adults' statements has, for a long time, been a controversial subject where the legal certainty in the court's free evaluation has been in question. In rape cases it is common that they lack direct evidence. The entire prosecution is then forced to build on the complainant’s statement, but how accurate is the judge in determining whether a state

Abstract COPD is a major cause of chronic morbidity and mortality throughout the world. It is a preventable and treatable disease. Smoking is the most commonly encountered risk factor for COPD and the habit now unfortunately starts at earlier ages than before. There is a strong necessity to diagnose COPD in early stages before symptoms present themselves. MRI with hyperpolarized 3He using diffusio