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Background: Wasting is a common complication of kidney failure that leads to weight loss and poor outcomes. Recent experimental data identified parathyroid hormone (PTH) as a driver of adipose tissue browning and wasting, but little is known about the relations among secondary hyperparathyroidism, weight loss, and risk of mortality in dialysis patients. Methods: We included 42,319 chronic in-centr
Context. After more than 50 years, astronomical research still struggles to reconstruct the history of lithium enrichment in the Galaxy and to establish the relative importance of the various 7Li sources in enriching the interstellar medium (ISM) with this fragile element. Aims. To better trace the evolution of lithium in the Milky Way discs, we exploit the unique characteristics of a sample of op
District heating and cooling are considered effective solutions to decarbonise the energy use in the building sector. The latest generation of district heating and cooling also increases the potential of integrating heat pumps and chillers in each building substation. The benefits of such integration are the reduction of network temperature and distribution losses; the recovery of waste heat throu
Support for developing a work identity hasbeen shown to be essential for the recovery process ofyoung adults with mental health problems. Sinceresearch shows that the development of a student roleduring the educational years for these young adultsmay be interrupted, this time period may be relevant toexplore in order to support career development and thecritical transition to adulthood for this ta
Synthetic glucocorticoids (GCs) are widely used in the variety of dosages for treatment of premature infants with chronic lung disease, respiratory distress syndrome, allergies, asthma, and other inflammatory and autoimmune conditions. Yet, adverse effects such as glucocorticoid-induced osteoporosis and growth retardation are recognized. Conversely, 2-oxoglutarate (2-Ox), a precursor of glutamine,
Eukaryotic phytoplankton exhibit an enormous species richness, displaying a range of phylogenetic, morphological and physiological diversity. Yet, until recently, very little was known about the diversity, genetic variation and evolutionary processes within species and populations. An approach to explore this diversity and to understand evolution of phytoplankton is to use population genetics as a
Background: There are currently no methods in clinical use that can detect early systemic dissemination of urothelial tumor cells. Objective: To evaluate measurement of circulating tumor cells (CTCs) as a biomarker for disseminated disease in patients with advanced bladder cancer. Design, setting, and participants: Between March 2013 and October 2015, 88 patients were prospectively included in the
This study focuses on communication and conceptions of obstetric care to address the postulates that immigrant women experience sensitive care through the use of an ethnically congruent interpreter and that such women prefer to meet health providers of the same ethnic and gender profile when in a multiethnic obstetrics care setting. During 2005-2006, we conducted in-depth interviews in Greater Lon
In this study, we examine the development of age at leaving the parental household in Sweden between the years 1830-1959. We utilize individual-level longitudinal data from two geographically and socioeconomically different regions: the county of Scania in the very south of Sweden, and Västerbotten to the north. We use descriptive and multivariate analyses to investigate how determinants, such as
The European spruce bark beetle (Ips typographus L.) is a major disturbance agent in Norway spruce (Picea abies (L.) Karst) forests in Europe and it is estimated that a changing climate will result in more severe outbreaks in the future. To reduce the risk of large outbreaks it is important to have methods that enable early detection of bark beetle attacks to help forest managers to prevent popula
The purpose of this paper is to interpret an American military media strategy designed for the Iraq war from a perspective drawing on recent theoretical discussions of space and time. The material consists of a short white paper that was declassified under the Freedom of Information Act and published by the NSA in 2007. It outlines a ‘Rapid Reaction Media Team’ which was tasked with designing and
Objectives: Audiologists provide professional contact and support between appointments to clients with hearing impairment using telephone and e-mail, but more advanced and flexible technological platforms are also possible. The present study aimed to evaluate the clinical application of an Internet-based support system for audiologists and their first-time hearing aid clients. Design: An Internet-
This dissertation examines the labor market outcomes of a population of natives and immigrants in Sweden from 1968 and until 2001. Previous research has consistently pointed to the importance of an individual’s country of origin, without being able to fully explain why this is the case. The standard approach is to use the country of origin as a way to measure everything occurring prior to migratio
Introduction: The prevalence of overweight and obesity in children and adolescents continues to rise, and there is a lack of long-term follow-up to clarify health and well-being trajectories into adolescence and adulthood. This study investigated anthropometry and quality of life (QoL) trajectories in 7-14-year-old vulnerable children three years after attending a lifestyle camp. Methods: Vulnerab
Internet has made information more easy to get, but also more difficult to retrieve. There is a need for information retrieval systems that assure accurate, reliable and up to date information. Quite a number of both commercial and non commercial search services has been developed on the Internet. We have made a qualitative study of one for-pay product in particular, NetS k, produced by BTJ (Bibli
Förstainstansrättens dom i målet Microsoft mot Kommissionen har gett upphov till många konkurrensrättsliga frågor, bl.a. gällande Microsofts tying av Windows Media Player till sitt operativsystem Windows. Denna uppsats för framförallt ett resonemang kring frågan om huruvida de ”traditionella” EG-rättsliga metoder som idag används vid bedömningen av kopplingsförbehåll (tying) är förlegade när dessa
Aims/hypothesis: Type 1 and type 2 diabetes differ with respect to pathophysiological factors such as beta cell function, insulin resistance and phenotypic appearance, but there may be overlap between the two forms of diabetes. However, there are relatively few prospective studies that have characterised the relationship between autoimmunity and incident diabetes. We investigated associations of a
We report here on a peptide hydrogel system, which in contrast to most other such systems, is made up of relatively short fibrillar aggregates, discussing resemblance with colloidal rods. The synthetic model peptides A8K and A10K, where A denotes alanine and K lysine, self-assemble in aqueous solutions into ribbon-like aggregates having an average length 〈L〉 on the order of 100 nm and with a diame
Background: Existing research has shown that those ageing with severe mental illness face significant challenges in daily life. Attendance at community-based day centres (DCs) is offered to support daily structure and break isolation. However, little is known about the experiences of those receiving this type of support while transitioning into retirement age. Aim: To explore experiences of everyd
Research on business models for sustainability (BMfS) has primarily focused on the conceptual aspects and sustainability potential of BMfS rather than their actual impact. There is a need to understand whether BMfS have less environmental impact on society than conventional business models and in what context and conditions they can reduce impact. This research conducted a systematic literature re
