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Predict with Confidence: Application of a Bayesian-Based Assimilation Framework to Optimise Wetland CH4 Emissions from a Terrestrial Ecosystem

Uncertainty in our calculations of a system reveals the limits of our knowledge. This limitation makes model representations of the Earth system challenging and our predictions less reliable. However, despite appearing chaotic and non-linear, a system always follows a deterministic trajectory, which can often be expressed probabilistically. Building on this concept, this thesis applies data assimi

Plasma Phosphorylated Tau 217 and Aβ42/40 to Predict Early Brain Aβ Accumulation in People Without Cognitive Impairment

Importance: Phase 3 trials of successful antiamyloid therapies in Alzheimer disease (AD) have demonstrated improved clinical efficacy in people with less severe disease. Plasma biomarkers will be essential for efficient screening of participants in future primary prevention clinical trials testing antiamyloid therapies in cognitively unimpaired (CU) individuals with initially low brain β-amyloid (

Did the Bronze Age deforestation of Europe affect its climate? A regional climate model study using pollen-based land cover reconstructions

This paper studies the impact of land use and land cover change (LULCC) on the climate around 2500 years ago (2.5 ka), a period of rapid transitions across the European landscape. One global climate model was used to force two regional climate models (RCMs). The RCMs used two land cover descriptions. The first was from a dynamical vegetation model representing potential land cover, and the second

Mechanisms Underlying the Specification of Definitive Hematopoiesis

Hematopoietic stem cells (HSCs) maintain blood through self-renewal and differentiation. Although HSC transplantation is the only cure for various blood disorders, generating and maintaining HSCs in vitro remains challenging, partly due to a limited understanding of the cellular and molecular mechanisms underlying human HSC ontogeny. In embryos, definitive HSCs arise from hemogenic endothelium via

Diclofenac for acute postoperative pain in children

Background: Many children undergo various surgeries, which often lead to acute postoperative pain. This pain influences recovery and quality of life. Non-steroidal anti-inflammatory drugs (NSAIDs), specifically cyclo-oxygenase (COX) inhibitors such as diclofenac, can be used to treat pain and reduce inflammation. There is uncertainty regarding diclofenac's benefits and harms compared to placebo or

What Encourages Academic Staff to Engage in Systematic, Sustained Change in Teaching Practices?

Representing an international, multi-institutional research team, the panel presents a theoretical framework for understanding what prompts academic staff/faculty to change towards sustained use of pedagogies that make a meaningful difference in student learning. The theory grows out of a synthesis of literature on: the role of leadership and resources in emerging changes to teaching practices (Gi

Human motor control, autonomic and decision processes under physical and psychological stress. Instinctive, reflexive and adaptive aspects.

The stress response is governed by automatic neurological and hormonal processes that occur before we become consciously aware of a dangerous situation. If stress ensues for 15-30 seconds, the hormonal processes may have progressed so far that recovery takes an hour or longer instead of minutes. Stress can affect our behavior and in certain professions, such as the police force and emergency servi

Taking Care of Business: A Study of the Governing of Care Choice Systems in Swedish Home Care

This study provides an account of the introduction of care choice systems into the provision of home care by Swedish municipalities. Care choice systems in elder care are at the centre of a conflict about the broader principles of the welfare state. Studying them is thus a way of revealing the outlines of this conflict. In this thesis, I show how the introduction of care choice systems changes the

Borrowability, inheritance, and semantic change in the Indo-European and Caucasian vocabulary for hunting, farming, and technology

Vocabulary for subsistence and technology may vary a great deal in their degree of borrowability, depending on time, place, inherent subsistence and technology, and the situation of the borrowing. In cross-linguistic typological studies of borrowability, these words tend to group somewhere from middle to high in borrowability, depending on lexical concept (Haspelmath & Tadmor, 2009).We have co

Unthinking sustainability through resourcification studies

In a world of nearly 10 billion people, competition for the conditions of life and wealth can only accelerate. Our contention is that with such increasing competition, more and more material as well as immaterial things will be turned into resources – a process that we suggest to label resourcification.Resourcification is not another term for processes of economisation such as commodification and

Errors in medication history at hospital admission : Prevalence and predicting factors

Background: An accurate medication list at hospital admission is essential for the evaluation and further treatment of patients. The objective of this study was to describe the frequency, type and predictors of errors in medication history, and to evaluate the extent to which standard care corrects these errors.Methods: A descriptive study was carried out in two medical wards in a Swedish hospital

Patenting human DNA sequences in Europe and the US - A comparative analysis of patentability requirements for nucleic acid sequences with special emphasis on novelty and inventive step

DNA is presently at the centre of a storm. On the one hand, the breathtaking development of DNA related sciences during the last decades led to a technological and medical revolution. Due to the far reaching possibilities connected to this technology, it is the focus of many people’s interest and one source of the hope that one day we will find cures for terrible illnesses. Unsurprisingly, DNA rel

Spring photosynthetic recovery of boreal Norway spruce under conditions of elevated [CO2] and air temperature

Accumulated carbon uptake, apparent quantum yield (AQY) and light-saturated net CO2 assimilation (A(sat)) were used to assess the responses of photosynthesis to environmental conditions during spring for three consecutive years. Whole-tree chambers were used to expose 40-year-old field-grown Norway spruce trees in northern Sweden to an elevated atmospheric CO2 concentration, [CO2], of 700 mu mol C

The potential transient dynamics of forests in New England under historical and projected future climate change

Projections of vegetation distribution that incorporate the transient responses of vegetation to climate change are likely to be more efficacious than those that assume an equilibrium between climate and vegetation. We examine the non-equilibrium dynamics of a temperate forest region under historic and projected future climate change using the dynamic ecosystem model LPJ-GUESS. We parameterized LP

Late-Glacial and Holocene forest dynamics at Steregoiu in the Gutaiului Mountains, Northwest Romania

Pollen analyses and AMS C-14 measurements were performed on lacustrine sediments and peat deposits from the former crater lake Steregoiu in a mid-altitude area in the Gutaiului Mountains in NW Romania in order to provide a detailed reconstruction of the vegetational development of the area during the Late-Glacial and Holocene. The bottom sediments are siliciclastic and were deposited probably duri

Means to Optimize the Nutritional Properties of Starch in Potato Products - Impact on glycaemia, satiety and resistant starch content

Popular Abstract in Swedish Potatis har varit, och är fortfarande ett viktigt baslivsmedel i svensk kosthållning. Det finns många sorter med olika egenskaper vilket bidrar till dess variationsrikedom. Potatisen är en rik källa till stärkelse, kostfibrer samt vitaminer och mineraler, t ex C-vitamin och järn. En invändning mot potatis ur nutritionell synvinkel är att stärkelsen lätt bryts ned av enzDespite decreased consumption potatoes still constitute an important staple in the Swedish diet. An objection to potatoes and potato products from a nutritional point of view is the ease by which the starch is digested and absorbed in the gastrointestinal tract. This results in unfavourably high glycaemic and insulinaemic responses (glycaemic index, GI and insulinaemic index, II, respectively). Su

Låsta bevis: En nyckelfråga? - En studie av krypterat material som bevismedel i brottmål

Åtkomst till bevismaterial är avgörande för att förverkliga det straffrättsliga ansvaret. Idag är en stor del av detta bevismaterial digitalt och i syfte att skydda och hemlighålla sådan information används i allt större utsträckning kryptering. Kryptering, som enklast möjligt kan sägas utgöra den digitala versionen av att låsa in material i ett kassaskåp, innebär att man utan den särskilda dekrypBeing able to access evidence is crucial for the realisation of responsibility under criminal law. In today’s world, a large part of what can potentially be evidence is stored digitally. In order to protect and keep digital information confidential, encryption is becoming widespread. Encryption, put simply, can be said to be the digital version of locking material in a safe, and basically means th

May the Strategy be with you: Strategi och struktur i nystartade företag

Examensarbetets titel: May the Strategy be with you: Strategi och struktur i nystartade företag Seminariedatum: 2016-01-14 Ämne/kurs: FEKH19 Företagsekonomi: Examensarbete i Strategic Management, 15 HP Författare: Aron Johansson, Matilda Karlsson, Fabian Söderström Handledare: Christine Blomquist Nyckelord: Strategi, Struktur, Effectuation, Nystartade företag, Företags livscykler Syfte: SyftTitle: May the Strategy be with you: Strategy and structure in new business ventures Seminar date: 2016-01-14 Course: FEKH19 Degree Project Undergraduate level, Business Administration, Undergraduate level, 15 University Credit Points (UCP or ECTS-cr) Authors: Aron Johansson, Matilda Karlsson, Fabian Söderström Advisor: Christine Blomquist Key words: Strategy, Structure, Effectuation, New Bus

Modellering av tågnät på Arriva DK

Purpose: The purpose of this thesis is to develop two simulation models of Arrivas train network in Denmark to facilitate the process of timetabling. One of the models assumes deterministic times in the other model these times are stochastic. The purpose of the deterministic model is to evaluate if timetables are free from conflicts, a process that currently involves a lot of manual labor. The mai