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3D Verification of Dynamic and Breathing Adapted Radiotherapy using Polymer Gel Dosimetry

Popular Abstract in Swedish En cancerpatient kommer till sjukhuset för att genomgå en strålbehandlig. Sjukhusets personal tar bilder av patienten och identifierar tumörens placering och utbredning. Bilderna läggs in i ett datorprogram, som i sin tur simulerar en strålbehandling. Strålningsapparaten, dvs. linjäracceleratorn, har flera justerbara parametrar; strålfältets storlek, vinkeln på den infaPolymer gel dosimetry has been used since the 1990s, and several studies have shown that this detector system can be used for verification of static absorbed dose distributions in three dimensions (3D). Its unique properties, such as high resolution, normal tissue equivalence and independency of energy, field size and direction of the incident radiation, should also be advantageous for dosimetric

Cloud Studies with the Droplet Aerosol Analyzer

Climate change and atmospheric aerosols are a threat for human health and life. Reducing aerosol emissions would save human lives close to the aerosol source, but could lead to more death due to the implications of a warmer climate. Aerosol particles acting as cloud or ice nuclei can induce a change in cloud properties and thus indirectly induce a change in planetary albedo, which is considered th

Retail and fashion - A happy marriage? The making of a fashion industry research design

Fashion and retail ought to be a happy marriage. Yet several entrepreneurs in the field of fashion speak of a climate that is difficult to penetrate because of economic and cultural factors. For example, the chain store concept is an expression of the specific and current fashion situation in Sweden: democratic fashion that is cheap and accessible. At the same time, customers now demand personal,

High-resolution calculations of merging neutron stars - I. Model description and hydrodynamic evolution

We present the results of 3D high-resolution calculations of the last inspiral stages and the final coalescence of neutron star binary systems. The equations of hydrodynamics are solved using the smoothed particle hydrodynamics method with up to 106 particles. Using Newtonian gravity, but adding the forces emerging from the emission of gravitational waves, we focus on the impact of microphysics on

The effect of terbutaline on the absorption of pulmonary administered insulin in subjects with asthma

center dot People with mild and moderate asthma have been shown to absorb less inhaled insulin than healthy subjects. center dot In people with moderate asthma, the administration of a bronchodilator before inhalation of insulin has been shown to lead to increased uptake of inhaled insulin compared with no prior administration of bronchodilator. WHAT THIS STUDY ADDS center dot This study is the fi

Nordic perspective on System Integrity Protection Schemes in relation to capacity allocation

The urgent need to address climate change and pollution prompts societies worldwide to adopt carbon neutral energy and electrification. To facilitate this, a range of technologies and policies will be needed. Alternatives to traditional power grid reinforcement, such as grid-enhancing technologies and system automation, are particularly attractive due to their potentially low cost and fast deploym

Making Sense of Exploitation : Teenage Workers’ Experiences of Unpaid Labour in Low-Wage Service Jobs

This article explores the rationales through which teenage students make sense of and legitimise unpaid labour in low-wage service jobs, contributing to theorising how such exploitation becomes normalised as part of their working lives. Based on 40 in-depth interviews with working school students in Sweden, it focuses on experiences of wage theft and coercive extra shifts, understood as employer s

Influence of Corrosion Extent on Residual Tensile Strength and Corrosion Fatigue Properties of an Mg-Y-Nd Alloy Characterized by μCT

This study focuses on the influence of inhomogeneous corrosion on the quasi-static and cyclic properties of an Mg−Y−Nd alloy. Uniform corrosion is essential for biodegradable implant materials to avoid notching effects and premature failure. Previous studies on extruded Mg−3Y−3RE have shown a pitting tendency in Ringer’s solution at 37 °C. Tensile tests on pre-corroded samples with different corro

Higher target attainment for B-lactam antibiotics in patients with Gram-negative bloodstream infections when four times actual minimum inhibitory concentrations and epidemiological cutoff values are applied compared to clinical breakpoints

IntroductionBeta-lactam antibiotics are essential in the treatment of Gram-negative bloodstream infections. The effect of beta-lactam antibiotics depends on the time of unbound antibiotic concentration above the minimal inhibitory concentration (MIC). An antibiotic concentration above MIC during the whole dosing interval (100% ƒT > MIC) has been suggested as a target for severe infections. The aim

Tourism challenges within a high cost of living crisis

Living costs have been increasing at an unprecedented rate compared to average trends over the last decade due to increasing uncertainty from various global events, including the COVID-19 pandemic and geopolitical tensions. Previous research indicates that people prioritize essential consumption over leisure and tourism activities during high cost-of-living crises. However, prior studies have over

Evalutation of two commercial deep learning OAR segmentation models for prostate cancer treatment

Purpose or ObjectiveTo evaluate two commercial, CE labeled deep learning-based models for automatic organs at risk segmentation on planning CT images for prostate cancer radiotherapy. Model evaluation was focused on assessing both geometrical metrics and evaluating a potential time saving.Material and MethodsThe evaluated models consisted of RayStation 10B Deep Learning Segmentation (RaySearch Lab

Screening for prostate cancer : an update.

The introduction of total prostate-specific antigen (tPSA) testing in serum has revolutionized the detection and management of men with prostate cancer. This review will highlight some of the exciting new developments in the field of prostate cancer screening in general and from our SPORE research program at Memorial-Sloan Kettering Cancer Center. First, it is important to understand that the inhe

Radio för alla? : Inslag på engelska och andra språk i Sveriges Radios svenskspråkiga radioprogram

Radio for everyone? Passages in English and other languages in Swedish publicservice radioThis article focuses on Swedish public service radio (Sveriges Radio, SR) and howinterviews in languages other than Swedish are given in SR. In the article, the result of a close analysis of 42 hours of broadcasting from SR is presented. All in all, a dozen languages are identified; however, English clearly d

European Multicentric Experience with Fenestrated-Branched ENDOvascular Stent-grafting after Previous FAILed Infrarenal Aortic Repair : the EU-FBENDO-FAIL Registry

OBJECTIVE: To report the mid-term outcomes of fenestrated-branched endovascular aneurysm repair (F-BEVAR) following a failed previous endovascular aneurysm repair (pEVAR) or previous open aneurysm repair (pOAR).METHODS: Data from consecutive patients who underwent F-BEVAR for pEVAR or pOAR from 2006-2021 from 17 European vascular centres were analyzed. Endpoints included technical success, major a

'The digital cardiologist' : How technology is changing the paradigm of cardiology training

In the same way that the practice of cardiology has evolved over the years, so too has the way cardiology fellows in training (FITs) are trained. Propelled by recent advances in technology-catalysed by COVID-19-and the requirement to adapt age-old methods of both teaching and healthcare delivery, many aspects, or 'domains', of learning have changed. These include the environments in which FITs wor

Clients and cases: ambiguity and the division of labour in professional service firms

PurposeBy drawing on a detailed case study of the work of tax consultants, the purpose of this paper is to develop a more detailed understanding of the role of ambiguity in professional work, and its relationship to the division of labour in professional service firms (PSFs).Design/methodology/approachThe paper is based on a three-year, longitudinal interpretive case study comprising 42 interviews

Debatten om det kommunala självstyret 1978 och 1998. En analys av en tillsynes odödlig debatt.

In this essay I will look at the independence of the Swedish municipalities. By looking at articles for the biggest journal in Sweden on this subject Kommun aktuellt I will look at the discussion for the years of 1978 and 1998 to see if one can draw some parallels in the debate and see if some subjects are always returning in the agenda for the independence. The autonomy of the Swedish municipalit

Does the 5–2-1 criteria identify patients with advanced Parkinson's disease? Real-world screening accuracy and burden of 5–2-1-positive patients in 7 countries

Background: The burden of Parkinson’s disease (PD) worsens with disease progression. However, the lack of objective and uniform disease classification challenges our understanding of the incremental burden in patients with advanced Parkinson’s disease (APD) and suboptimal medication control. The 5–2-1 criteria was proposed by clinical consensus to identify patients with advancing PD. Our objective

Effect of a Smoking and Alcohol Cessation Intervention Initiated Shortly Before Radical Cystectomy—the STOP-OP Study : A Randomised Clinical Trial

Background: Evidence concerning the reduction of postoperative complications due to smoking and alcohol drinking in patients undergoing radical cystectomy is incomplete. Objective: To evaluate the efficacy of a 6-wk smoking and/or alcohol cessation intervention, initiated shortly before surgery and continued until 4 wk after, in reducing complications. Design, setting, and participants: Between 20

Stability of oxaliplatin in chloride-containing carrier solutions used in hyperthermic intraperitoneal chemotherapy

PURPOSE: Oxaliplatin is increasingly becoming the chemotherapeutic drug of choice for the treatment of peritoneal malignancies using cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC). Oxaliplatin is unstable in chloride-containing media, resulting in the use of 5% dextrose as the carrier solution in these procedures. Exposure of the peritoneum to 5% dextrose during pe