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Many bird species demonstrate a variable mating system, with some males being monogamously mated and other males able to attract more than one mate. This variation in avian mating systems is often explained in terms of potential costs of sharing breeding partners and compensation for such costs. However, whenever there is a difference in the optimal mating system for males and females, a sexual co
1. The sense of smell is crucial for fitness of most animals, enabling them to find mates, food and egg laying sites and to stay away from danger. Hence, odour molecules are detected by sensitive and specific olfactory sensory neurons (OSNs). In insects, the OSNs are stereotypically grouped into olfactory sensilla located mainly on the antennae. The functional significance of this co-localization
In the present study we investigate the fate of citalopram (CIT) at neutral pH using advanced water treatment technologies that include O(3), ClO(2) oxidation, UV irradiation and Fenton oxidation. The ozonation resulted in 80% reduction after 30min treatment. Oxidation with ClO(2) removed>90% CIT at a dosage of 0.1mgL(-1). During UV irradiation 85% reduction was achieved after 5min, while Fenton w
Evaluating potentially analgesic effects of drugs and various treatments is critically dependent on valid animal models of pain. Since primary somatosensory (SI) cortex is likely to play an important role in processing sensory aspects of pain, we here assess whether monitoring SI cortex nociceptive C fibre evoked potentials can provide useful information about central changes related to hyperalges
We investigated the immunosuppressive effects of the dihydroortate dehydrogenase (DHODH) inhibitor compounds ABR-222417 and ABR-224050 from Active Biotech (Sweden). We verified the inhibitory effects of these compounds on the proliferation of CD4(+) and CD8(+) T-cells in vivo by using superantigen staphylococcus enterotoxin A (SEA)-mediated proliferation test. To evaluate their efficacy, the compo
The free volume changes of poly[1-(trimethyl-silyl)-1-propyne] (PTMSP) treated in supercritical CO2 (scCO(2)) were investigated with positron annihilation lifetime spectroscopy (PALS). CO2 is known to plasticize and increase the free volume size of a broad range of polymers. In this work dense PTMSP films were treated with scCO(2) under different pressures and temperatures, resulting in the enlarg
Heparan sulfate inhibits the proliferation of normal human lung fibroblasts (HFL-1) but not of a human lung carcinoma cell-line (A549). in this study we investigated possible mechanisms and structural requirements by which anti proliferative heparan sulfates exerts its effects on binding, uptake and subcellular localisation. Both HFL-1 and A549 cells were incubated with I-125- or rhodamine-labeled
A series of triclinic Fe1−xAlxVO4 phases with 0 <= x <= 1 were prepared and used in the oxidation of methanol to formaldehyde. The activity measurements revealed that both the activity and especially the selectivity to formaldehyde increased with time of operation for at least 16 h, indicating restructuring of the catalysts. Characterisation of the catalysts with XRD, XANES, and electron microscop
Nuclear spin relaxation by intermolecular dipole–dipole interactions between macromolecular and solvent nuclear moments forms the basis of a widely used method for investigating macromolecular solvation. In particular, intermolecular cross-relaxation [or nuclear Overhauser effect (NOE)] between protein and water protons has been used to probe the mobility of water molecules interacting with the pr
BACKGROUND: The method of treatment of aortic valve stenosis in early infancy is still controversial. This study was performed to evaluate short-term and long-term outcome in our center during a 14-year period.METHODS: Between 1991 and 2004, 64 consecutive patients younger than 3 months old underwent open surgical commissurotomy because of aortic valve stenosis. Median age was 18 days (range, 1 to
Background: Sentinel lymph node biopsy is an established staging method in early breast cancer. After a negative biopsy, most institutions will not perform a completion axillary dissection. The present study reports the current axillary recurrence (AR) rate, overall and disease-free survival in the Swedish Multicenter Cohort Study. Methods: From 3534 patients with primary breast cancer <= 3 cm pro
Objectives The aim of the present study was to test whether construction workers, who are known to have a relatively higher risk of cardiovascular disease (CVD), had higher concentrations of cortisol in saliva and a lower relative variability when compared with white-collar workers. Methods Data from two groups of male construction workers with physically demanding job assignments, with either reg
We reported previously the formation of microtears in an in vivo loaded Flexor Digitorum Profundus (FDP) rabbit tendon with a repetition rate of 60 repetitions per minute and a peak force of 15% of maximum peak tetanic force for 80 cumulative hours. Tear area as a percent of tendon area, tear density (tears/mm(2)), and mean tear size (mu m(2)) were higher in tendons from the loaded limb compared t
Ammoxidation of 3-picoline was studied on reduced V-Ti-O catalysts with V6O13 as the major vanadium oxide. The results showed that the initial activity as a function of the TiO2 content reached a maximum at 50–60 mole% TiO2. It is proposed that there is maximum contact between the vanadium and titanium phases at this composition, which results in a weakening of the (VO)3+ surface bond. The selecti
Here we report on the development of a proteomic platform utilizing a piezoelectric flow-through dispensing unit made from silicon microstructures. The use of a novel surface coating, where matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI MS) targets were uniformly precoated with a thin film of matrix/nitrocellulose, made the sample preparation straightforward an
The aim of this study was to determine the threshold of fracture probability at which interventions became cost-effective in women based on data from the UK. We modelled the effects of an intervention costing pound350 per year given for 5 years that decreased the risk of all osteoporotic fractures by 35% followed by a waning of effect (offset time) for a further 5 years. Sensitivity analyses inclu
We have analyzed the M-bcr breakpoint position in 133 Philadelphia-positive chronic myeloid leukemia patients and correlated the findings with clinical, hematologic, and cytogenetic data. We also investigated the splicing pattern of the BCR-ABL mRNA in 30 patients, using reverse transcriptase PCR. No statistically significant differences were found between breakpoint position within M-bcr and clin
