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Differences in the uptake and nuclear localization of anti-proliferative heparan sulfate between human lung fibroblasts and human lung carcinoma cells

Heparan sulfate inhibits the proliferation of normal human lung fibroblasts (HFL-1) but not of a human lung carcinoma cell-line (A549). in this study we investigated possible mechanisms and structural requirements by which anti proliferative heparan sulfates exerts its effects on binding, uptake and subcellular localisation. Both HFL-1 and A549 cells were incubated with I-125- or rhodamine-labeled

Oxidation of methanol to formaldehyde over a series of Fe(1-x)Al(x)-V-oxide catalysts

A series of triclinic Fe1−xAlxVO4 phases with 0 <= x <= 1 were prepared and used in the oxidation of methanol to formaldehyde. The activity measurements revealed that both the activity and especially the selectivity to formaldehyde increased with time of operation for at least 16 h, indicating restructuring of the catalysts. Characterisation of the catalysts with XRD, XANES, and electron microscop

Cross-relaxation between macromolecular and solvent spins: the role of long-range dipole couplings.

Nuclear spin relaxation by intermolecular dipole–dipole interactions between macromolecular and solvent nuclear moments forms the basis of a widely used method for investigating macromolecular solvation. In particular, intermolecular cross-relaxation [or nuclear Overhauser effect (NOE)] between protein and water protons has been used to probe the mobility of water molecules interacting with the pr

Axillary recurrence rate after negative sentinel node biopsy in breast cancer - Three-year follow-up of the Swedish Multicenter Cohort Study

Background: Sentinel lymph node biopsy is an established staging method in early breast cancer. After a negative biopsy, most institutions will not perform a completion axillary dissection. The present study reports the current axillary recurrence (AR) rate, overall and disease-free survival in the Swedish Multicenter Cohort Study. Methods: From 3534 patients with primary breast cancer <= 3 cm pro

Effect of repetition rate on the formation of microtears in tendon in an in vivo cyclical loading model

We reported previously the formation of microtears in an in vivo loaded Flexor Digitorum Profundus (FDP) rabbit tendon with a repetition rate of 60 repetitions per minute and a peak force of 15% of maximum peak tetanic force for 80 cumulative hours. Tear area as a percent of tendon area, tear density (tears/mm(2)), and mean tear size (mu m(2)) were higher in tendons from the loaded limb compared t

Geon05 syllabus english 2016-05-03

Kursguide - Course Syllabus Details of approval The syllabus was approved by Study programmes board, Faculty of Science on 2016- 04-04 to be valid from 2016-07-01, autumn semester 2016. General Information The course is an elective second cycle course for a degree of Master of Science (120 credits) in Geology. Language of instruction: English Learning outcomes The general aim of the course is to p

https://www.geology.lu.se/sites/geology.lu.se/files/geon05_syllabus_english_2016-05-03_.pdf - 2026-05-09

Beyond the Clouds : S3 as the most distant extended Milky Way stream, not of LMC origin

Context. While the influence of the LMC on Milky Way (MW) stellar streams has been extensively studied, streams associated with the Clouds have received far less attention. Beyond the Magellanic Stream, only four stream candidates (S1–S4) have been reported. Aims. We focus on the S3 stream, a long (~30°) and narrow (~1.2°) structure at 60–80 kpc that is nearly aligned with the LMC. Our goals are:

Msc project siljan per moller

(Microsoft Word - MS project 'drainage of the Siljan basin at \305ker\366'_ ver 2.docx) 1 A drainage event of ancient Lake Siljan at Åkerö in Leksand, Dalarna – a scenario test Introduction The Siljan area, situated in the central part of the Dalarna province, south-central Sweden (Fig. 1), is of remarkable geologic interest, not least indicated by the presently ongoing process of making it part o

https://www.geology.lu.se/sites/geology.lu.se/files/msc_project_siljan_per_moller.pdf - 2026-05-09

Bacheng2021

Instructions for applicants to the Bachelor Programme of Fine Arts, 180 credits 2021/2022 Deadline for applications 1 March 2021 v 1.1 Deadlines and general information about applications to the Bachelor of Fine Arts programme at Malmö Art Academy Deadline 1 March 2021 for applications including 1. Submitted application at https://www.universityadmissions.se 2. Uploading of work samples in the Mal

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/2021-01/bacheng2021.pdf - 2026-05-09

IAC-technical-equipment-2025

IAC-technical-equipment-2023_v1 1 IAC technical equipment 2025 IAC provides a wide variety of audiovisual equipment. Always consult our technical staff in good time regarding the needs of your project. There are lots of other equipment and tools at IAC that could be interesting for your project that is not listed below. For some technical equipment and facilities, you must be given basic tutorials

https://www.iac.lu.se/sites/iac.lu.se/files/2025-04/IAC-technical-equipment-2025.pdf - 2026-05-09

Neuroimaging infrastructure Report 2021-Neuroimaging

Microsoft Word - Neuroimaging infrastructure report 2021-Neuroimaging.docx Multipark infrastructure report form 2021 Neuroimaging Danielle van Westen, Markus Nilsson 1. Short description of the infrastructure. The equipment for neuroimaging in humans focuses on magnetic resonance imaging (MRI) and positron emission tomography (PET). In addition, however not included here, preclinical equipment com

https://www.multipark.lu.se/sites/multipark.lu.se/files/2021-06/Neuroimaging_infrastructure%20report%202021-Neuroimaging.pdf - 2026-05-09

Statistical-mechanics-2

Microsoft Word - STATISTICAL MECHANICS2.doc 31 4. Two-level systems 4.1 Introduction Two-level systems, that is systems with essentially only two energy levels are important kind of systems, as at low enough temperatures, only the two lowest energy levels will be involved. Especially important are solids where each atom has two levels with different energies depending on whether the electron of th

https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2025-01/statistical-mechanics-2.pdf - 2026-05-09

Surveillance Bias in Cancer Risk after Unrelated Medical Conditions : Example Urolithiasis

We analysed cancer risks in patients with urinary tract stones but some features of the generated results alarmed us about possible surveillance bias, which we describe in this report. We used nationwide Swedish hospital records to identify patients with urinary tract stones (N = 211,718) and cancer registration data for cancer patients for years 1987 to 2012. Standardized incidence ratios (SIRs)

Johan Ekeblad : Kulturskridning, mentalitet, genre

Johan Ekeblad was a Swedish diplomat and nobleman during the period of the Swedish Empire in the 17th century who is mostly known for his letters, written in an impressionistic and highly modern style. This paper aims to treat Johan Ekeblad and his writing as a representative of a new form of mentality that emerged amongst Swedes when Sweden due to its new power reemerged on the European scene. Th

Beyond the Hofmeister Series : Ion-Specific Effects on Proteins and Their Biological Functions

Ions differ in their ability to salt out proteins from solution as expressed in the lyotropic or Hofmeister series of cations and anions. Since its first formulation in 1888, this series has been invoked in a plethora of effects, going beyond the original salting out/salting in idea to include enzyme activities and the crystallization of proteins, as well as to processes not involving proteins lik

No title

Diagnostic reference levels are the main and the most effective tools of optimization of the radiation protection of patients from medical exposure. Diagnostic reference levels should be established based on theresults of dedicated dose surveys, allowing evaluating typical patient dose distributions in a selected dose quantity for the selected X-ray examinations. The aim of the current study was t

The ubiquity and type diversity of papillomaviruses in normal skin

Popular Abstract in Swedish Papillomvirus infekterar ett brett spektrum av ryggradsdjur, såsom människa, olika ap-arter, ko, älg, elefant, ren och bofink. Dessa virus kan ge så vitt skilda symptom som cancer och vårtor. De indelas efter vilken art de infekterar, och inom arterna efter skillnad i DNA-sekvens mellan olika isolat (typer). Hittills har 92 humana papillomvirus (HPV) typer beskrivits, oPapillomaviruses are a diverse, epitheliotropic group of viruses. Some genotypes are the main cause of anogenital cancer in humans; others can induce skin lesions. In order to investigate the occurrence of subclinical skin infections with human papillomavirus (HPV), a pair of degenerate primers (FAP59/64) was designed. Moist cotton-tipped swabs were used as a gentle method of sample collection. Di

The spleen dictates platelet destruction, anti-platelet antibody production, and lymphocyte distribution patterns in a murine model of immune thrombocytopenia

For many years, splenectomy has been used to treat immune thrombocytopenia (ITP), and this procedure benefits approximately two-thirds of the treated patients. Although splenectomy may raise platelet counts, antibody-coated platelets and cytotoxic T lymphocytes appear to persist or can change over time. To better understand how the spleen may affect anti-platelet immune responses, we used a murine

Prognostic impact of epigenetic classification in chronic lymphocytic leukemia : The case of subset #2

ABSTRACT: Based on the methylation status of 5 single CpG sites, a novel epigenetic classification of chronic lymphocytic leukemia (CLL) was recently proposed, classifying CLL patients into 3 clinico-biological subgroups with different outcome, termed memory like CLL (m-CLL), naïve like CLL (n-CLL), and a third intermediate CLL subgroup (i-CLL). While m-CLL and n-CLL patients at large corresponded

Grey Matter Segmentation in Spinal Cord MRIs via 3D Convolutional Encoder Networks with Shortcut Connections

Segmentation of grey matter in magnetic resonance images of the spinal cord is an important step in assessing disease state in neurological disorders such as multiple sclerosis. However, manual delineation of spinal cord tissue is time-consuming and susceptible to variability introduced by the rater. We present a novel segmentation method for spinal cord tissue that uses fully convolutional encode