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5-Hydroxymethylfurfural from fructose : An efficient continuous process in a water-dimethyl carbonate biphasic system with high yield product recovery

Bio-based 5-hydroxymethylfurfural (5-HMF) and its derivatives have attracted enormous attention due to their valuable market potential. Production of pure 5-HMF is challenging owing to the high reactivity of its functional groups and formation of by-products. In this study, an efficient continuous process for 5-HMF production in a biphasic system and its recovery at high yield and selectivity was

Negative associations for fasting blood glucose, cholesterol and triglyceride levels with the development of giant cell arteritis

Objectives. To investigate metabolic features that may predispose to GCA in a nested case-control study. Methods. Individuals who developed GCA after inclusion in a population-based health survey (the Malmö Preventive Medicine Project; N ¼ 33 346) were identified and validated through a structured review of medical records. Four controls for every validated case were selected from the database. Re

Important role of forest disturbances in the global biomass turnover and carbon sinks

Forest disturbances that lead to the replacement of whole tree stands are a cornerstone of forest dynamics, with drivers that include fire, windthrow, biotic outbreaks and harvest. The frequency of disturbances may change over the next century with impacts on the age, composition and biomass of forests. However, the disturbance return time, that is, the mean interval between disturbance events, re

A minimal model for the latitudinal diversity gradient suggests a dominant role for ecological limits

The latitudinal diversity gradient (LDG) is one of Earth’s most iconic biodiversity patterns and still one of the most debated. Explanations for the LDG are often categorized into three broad pathways in which the diversity gradient is created by (1) differential diversification rates, (2) differential carrying capacities (ecological limits), or (3) differential time to accumulate species across l

Improved Outcomes After Regional Implementation of Sepsis Alert : A Novel Triage Model

OBJECTIVES: To assess whether the triage model Sepsis Alert for Emergency Departments results in improved initial care of patients with severe infections. DESIGN: Interventional study comparing patient care before and after the start of a new triage model, including 90-day follow-up. SETTING: Eight emergency departments in Skåne County, Sweden. SUBJECTS: Patients with suspected severe infection. I

Novel methodology for the evaluation of symptoms reported by patients with newly diagnosed atrial fibrillation : Application of natural language processing to electronic medical records data

Introduction: Understanding symptom patterns in atrial fibrillation (AF) can help in disease management. We report on the application of natural language processing (NLP) to electronic medical records (EMRs) to capture symptom reports in patients with newly diagnosed (incident) AF. Methods and Results: This observational retrospective study included adult patients with an index diagnosis of incide

Morphological changes of endometriomas during pregnancy and after delivery detected using ultrasound

Objective: To assess changes in morphology and size of endometriomas during pregnancy and after delivery.Design: This was a prospective observational cohort study performed during 2013 - 2024 at a tertiary care center (Ultrasound Unit, Department of Obstetrics and Gynecology, Skane University Hospital, Malmo, Sweden). Women were offered repeated ultrasound examinations every month during pregnancy

Effects of endovascular cooling on infarct size in ST-segment elevation myocardial infarction : A patient-level pooled analysis from randomized trials

Objectives: This study sought to examine the relationship between temperature at reperfusion and infarct size. Background: Hypothermia consistently reduces infarct size when administered prior to reperfusion in animal studies, however, clinical results have been inconsistent. Methods: We performed a patient-level pooled analysis from six randomized control trials of endovascular cooling during pri

"A gentle push": barnets inskolning i förskolan

An absolute majority of all Swedish children begins to attend preschool at some point between the age of one and five. The acclimatisation to preschool means a great change in every small child's life. They leave all that is well known, the parent and their home, to face a whole new environment with new kids and adults to get to know and learn to trust. The purpose of this study has been to f

Kinematics with GAIA DR2 : The force of a dwarf

We use Gaia DR2 astrometric and line-of-sight velocity information combined with two sets of distances obtained with a Bayesian inference method to study the 3D velocity distribution in the Milky Way disc. We search for variations in all Galactocentric cylindrical velocity components (Vφ, VR, and Vz) with Galactic radius, azimuth, and distance from the disc mid-plane. We confirm recent work showin

Microfluidic Flow-Focusing for Size-Controlled Formation of Cubosomes

Cubosomes─colloidal dispersions of lipid inverted bicontinuous cubic phases─are promising nanosystems for advanced drug delivery applications. Here, we report on a microfluidic hydrodynamic flow-focusing approach for solvent exchange that enables the preparation of cubosomes with tunable size. The approach involves a preliminary step where the lipid phytantriol, the main building block, is first d

The Solo Tuba: Re-evaluating instruments, timbres and performance practices

This article explores how quantitative organological analysis can be implemented alongside historical musicology to help stimulate creativity in performance practice while promoting a diversity of timbre that is often lost amidst the hegemonic propagation of homogenized, normalized modern musical instruments. The tuba family provides an insightful case study demonstrating how the history and devel

Development-2014-akerblom

_ © 2014. Published by The Company of Biologists Ltd | Development (2014) 141, 1-9 doi:10.1242/dev.101659 1 ABSTRACT New neurons, originating from the subventricular zone, are continuously integrating into neuronal circuitry in the olfactory bulb (OB). Using a transgenic sensor mouse, we found that adult-born OB interneurons express microRNA-125 (miR-125), whereas the pre- existing developmentally

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/development-2014-akerblom.pdf - 2026-05-30

A comparison of the semiflexed (MTP) view with the standing extended view (SEV) in the radiographic assessment of knee osteoarthritis in a busy routine X-ray department

Objective. To compare the reproducibility of the standing extended view (SEV) (also known as the standing anteroposterior view) with the semiflexed, postero-anterior view [the 'metatarsophalangeal' (MTP)] view for assessing joint space width (JSW) and osteophytes in osteoarthritis of the knee when used in a busy routine X-ray department. Methods. Forty-seven patients (24 men) had both SEV and MTP

Blood pressure, body size and prostate cancer risk in the Swedish construction workers cohort

Data from prospective studies on blood pressure and prostate cancer risk are limited, and results are inconclusive. Baseline measurements of height, weight and blood pressure were available in 336,159 men in the Swedish Construction Workers cohort. During an average of 22.2 years of follow-up, 10,002 incident cases and 2,601 fatal cases of prostate cancer were identified in National registers. For

An increasing number of hand injuries in an elderly population - A retrospective study over a 30-year period

Background: Both the number and the proportion of elderly people in the society increase. The number of elderly subjects with a disability due to a disease has decreased resulting in more active elderly. Therefore, an increase in numbers of injury in the elderly population can be expected; a hypothesis that was investigated in the present study. Methods: Two-hundred sixteen patients with an age of

Optimal harmonic period assignment : complexity results and approximation algorithms

Harmonic periods have wide applicability in industrial real-time systems. Rate monotonic (RM) is able to schedule task sets with harmonic periods up to 100% utilization. Also, if there is no release jitter and execution time variation, RM and EDF generate the same schedule for each instance of a task. As a result, all instances of a task are interfered by the same amount of workload. This property

Base cations in the soil bank : Non-exchangeable pools may sustain centuries of net loss to forestry and leaching

Accurately quantifying soil base cation pool sizes is essential to interpreting the sustainability of forest harvests from element mass-balance studies. The soil-exchangeable pool is classically viewed as the bank of "available" base cations in the soil, withdrawn upon by plant uptake and leaching and refilled by litter decomposition, atmospheric deposition and mineral weathering. The operational

Predictors of Recurrent Ischemic Stroke in Patients with Embolic Strokes of Undetermined Source and Effects of Rivaroxaban Versus Aspirin According to Risk Status : The NAVIGATE ESUS Trial

Background: Embolic stroke of undetermined source (ESUS) identifies patients with cryptogenic ischemic stroke presumed due to embolism from several unidentified sources. Among patients with recent ESUS, we sought to determine independent predictors of recurrent ischemic stroke during treatment with aspirin or rivaroxaban and to assess the relative effects of these treatments according to risk. Met