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Dietary total antioxidant capacity and gastric cancer risk in the European prospective investigation into cancer and nutrition study

A high intake of dietary antioxidant compounds has been hypothesized to be an appropriate strategy to reduce gastric cancer (GC) development. We investigated the effect of dietary total antioxidant capacity (TAC) in relation to GC in the European Prospective Investigation into Cancer (EPIC) study including 23 centers in 10 European countries. A total of 521,457 subjects (153,447 men) aged mostly 3

Alveolar T-helper type-2 immunity in atopic asthma is associated with poor clinical control

Real-world evaluation studies have shown that many patients with asthma remain symptomatic despite treatment with inhaled corticosteroids (ICSs). As conventional ICSs have poor access to the peripheral airways, the aim of the present paper was to study the relationship between peripheral airway inflammation and clinical control in allergic asthma. Consequently, bronchial and transbronchial biopsie

Body fat, abdominal fat and body fat distribution related to cardiovascular risk factors in pre-pubertal children.

Aim We analysed whether total body fat, abdominal fat and body fat distribution are associated with higher composite risk factor scores for cardiovascular disease (CVD) in young children. Methods Cross-sectional study of 238 children aged 8-11 years. Total body fat (TBF) and abdominal fat mass (AFM) were measured by DXA. TBF was expressed as a percentage of body weight (BF%). Body fat distribution

Autism spectrum disorders and autisticlike traits: similar etiology in the extreme end and the normal variation.

CONTEXT: Autism spectrum disorders (ASDs) have been suggested to represent the extreme end of a normal distribution of autisticlike traits (ALTs). However, the evidence of this notion is inconclusive. OBJECTIVE: To study whether there are similar genetic and/or environmental etiologies behind ASDs and ALTs. DESIGN: A nationwide twin study. PARTICIPANTS: Consenting parents of all Swedish twins aged

Parental separation in childhood, social capital, and suicide thoughts and suicide attempts: A population-based study.

Studies of the association between parental separation in childhood and suicide thoughts and attempts are scarce. The aim of this study is to investigate associations between parental separation/divorce during childhood, and ever having had suicide thoughts and ever having made suicide attempt, adjusting for social capital and other covariates. In 2012 a cross-sectional public health survey was co

Direct subwavelength imaging and control of near-field localization in individual silver nanocubes

We demonstrate the control of near-field localization within individual silver nanocubes through photoemission electron microscopy combined with broadband, few-cycle laser pulses. We find that the near-field is concentrated at the corners of the cubes, and that it can be efficiently localized to different individual corners depending on the polarization of the incoming light. The experimental resu

Migration and health: a study of effects of early life experiences and current socio-economic situation on mortality of immigrants in Sweden.

Objectives. Previous research has demonstrated mortality differences between immigrants and natives living in Sweden. The aim of this study is to investigate the effects of early life conditions in the country of birth and current socio-economic conditions in adult life in Sweden on cardiovascular, cancer, all other cause and total mortality among immigrants and natives in Sweden. Design. The coho

A Missense Mutation in the Aggrecan C-type Lectin Domain Disrupts Extracellular Matrix Interactions and Causes Dominant Familial Osteochondritis Dissecans

Osteochondritis dissecans is a disorder in which fragments of articular cartilage and subchondral bone dislodge from the joint surface. We analyzed a five-generation family in which affected members had autosomal-dominant familial osteochondritis dissecans. A genome-wide linkage analysis identified aggrecan (ACAN) as a prime candidate gene for the disorder. Sequence analysis of ACAN revealed heter

The risk for depression in patients with ankylosing spondylitis: a population-based cohort study

Introduction: Depression is frequent in ankylosing spondylitis (AS) patients. However, epidemiological data about the potential increase in risk are lacking. This study compares the rate of doctor-diagnosed depression in a well defined cohort of AS patients to the general population seeking care. Methods: The Skane Healthcare Register comprises healthcare data of each resident in Region Skane, Swe

Working Environment and work retention

The project shows that the working environment is rarely the sole cause of early retirement, but working environment factors may explain a large fraction of the transition to disability pension in particular. Several working environment predictors of early retirement are well-documented in the Nordic countries, but workplace policies and activities to retain older workers rarely aim to improve the

A comparative study found that a seven-year school-based exercise programme increased physical activity levels in both sexes

Aim: This study assessed whether a Swedish school-based exercise intervention programme could increase total physical activity. Methods: We followed up 228 children who started school in 1998-2000 seven years later, when they had reached a mean age of 14.8. The 152 children (59% boys) at the intervention school did 200 minutes of physical education per week during that period, and the 76 children

Subjective health complaints and exposure to peer victimization among disabled and non-disabled adolescents : A population-based study in Sweden

AIMS: To investigate subjective health complaints (SHCs) (psychological and somatic, respectively) among disabled and non-disabled adolescents, focusing on the impact of traditional bullying and cyber harassment, and furthermore to report psychological and somatic SHCs across different types of disability.METHODS: Data from the public health survey of children and adolescents in Scania, Sweden, 20

Cost-effectiveness of infliximab versus conventional combination treatment in methotrexate-refractory early rheumatoid arthritis: 2-year results of the register-enriched randomised controlled SWEFOT trial.

OBJECTIVE: To estimate the incremental cost-effectiveness of infliximab versus conventional combination treatment over 21 months in patients with methotrexate-refractory early rheumatoid arthritis. METHODS: In this multicentre, two-arm, parallel, randomised, active-controlled, open-label trial, rheumatoid arthritis patients with <1 year symptom duration were recruited from 15 rheumatology clini

End-stage renal disease and low level exposure to lead, cadmium and mercury; a population-based, prospective nested case-referent study in Sweden

Background: Cadmium (Cd), lead (Pb), and mercury (Hg) cause toxicological renal effects, but the clinical relevance at low-level exposures in general populations is unclear. The objective of this study is to assess the risk of developing end-stage renal disease in relation to Cd, Pb, and Hg exposure. Methods: A total of 118 cases who later in life developed end-stage renal disease, and 378 matched

Photovoltaics with Piezoelectric Core-Shell Nanowires

We report on a theoretical discovery of a generic piezoelectric held in strained core shell compound semiconductor nanowires. We show, using both an analytical model and numerical simulations based on fully electroelastically coupled continuum elasticity theory, that lattice-mismatch-induced strain in an epiraxial core shell nanowire gives rise to an internal electric held along the axis of the na

Pulse transmission using leaky lens antenna and RTD-MOSFET wavelet generator

A leaky lens antenna system for short pulse applications is designed, fabricated and characterized. The antenna has very good phase center stability over large bandwidths. The leaky lens antenna is connected to an in-house wavelet generator to transmit 100 ps pulses centered at 57.5 GHz. It is shown that the antenna preserves the reference pulse shape and has very low dispersion.

Predictors of Psychiatric Hospitalization in Ex-Prisoners With Substance Use Problems: A Data-Linkage Study

This study analyzed predictors of psychiatric hospitalization in ex-prisoners with substance use problems (N = 4,081) assessed with the Addiction Severity Index and followed post-release for hospitalizations with psychiatric diagnoses (including suicide attempts). Thirty-four percent were hospitalized, and in Cox regression, several substance-related variables predicted hospitalization, including

Local structure of photoexcited bimetallic complexes refined by quantitative XANES analysis

Photoexcited states of a pyrazolate bridged PtPt dimer and a supramolecular RuCo complex with bipyridine-type ligands were studied using the pump-and-probe X-ray absorption spectroscopy method. The local structure refinement based on the fitting of XANES difference spectra has been performed. The theoretical analysis included the full multiple scattering calculations and the multidimensional inter