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Discordant Neural Xenografting: Analysis and Modulation of Immune Responses

Popular Abstract in Swedish Transplantation av dopaminceller från mänskliga foster kan förbättra funktionen hos patienter med Parkinsons sjukdom (Lindvall 1997, Björklund 2000a). Man har kunnat visa att transplantaten har återställt dopaminproduktionen i striatum till normala nivåer i flera fall, och till 70-80% av normalt i majoriteten av de patienter som transplanterats i Lund. Transplantaten haTransplantation of embryonic human neural tissue can restore function in patients with Parkinson’s disease, but there is a severe shortage of donor tissue which limits the applicability of the technique. Embryonic neural tissue from other species, xenogeneic tissue, would provide a readily accessible donor tissue with the potential to help patients if the immunological reactions in the host could

Evaluation of physical work capacity and leg muscle fatigue during exhaustive stair ascending evacuation

AbstractPhysical exhaustion can constrain human ascending work capacity and performance during emergency evacuation on stairs. The overall aim of this research was to explore and compare stair ascending capacities and physiological limitations during two different strategies: self-preferred pace in three different public stairways in the field, and controlled pace in a laboratory on a stair machin

Child and Adolescent Health From 1990 to 2015 : Findings From the Global Burden of Diseases, Injuries, and Risk Factors 2015 Study

Importance: Comprehensive and timely monitoring of disease burden in all age groups, including children and adolescents, is essential for improving population health.Objective: To quantify and describe levels and trends of mortality and nonfatal health outcomes among children and adolescents from 1990 to 2015 to provide a framework for policy discussion.Evidence Review: Cause-specific mortality an

Global gridded crop model evaluation : Benchmarking, skills, deficiencies and implications

Crop models are increasingly used to simulate crop yields at the global scale, but so far there is no general framework on how to assess model performance. Here we evaluate the simulation results of 14 global gridded crop modeling groups that have contributed historic crop yield simulations for maize, wheat, rice and soybean to the Global Gridded Crop Model Intercomparison (GGCMI) of the Agricultu

Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans

Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos

Disposal Behaviour and Local Support Systems

Disposal behaviour represent the last phase in the consumption cycle. From an environmental point of view it is extremely important to know the factors behind individual behaviour in waste handling. There are several aspects of interest, for example willingness of waste separation and re-use of products. The aim of this article is to analyse the importance of environmental concern, disposal behavi

Crowd evacuation in high-density scenarios

Nowadays, is becoming increasingly frequent holding events in outdoor environments, involving a large number of people, even though these spaces were not designed from a safe prospective, in the way that safety is defined today. In such events, high density conditions is an ongoing issue, as the evacuation becomes very complex, due to the space design and the interaction among the pedestrians. It

Comparative analysis of the understanding of 'expertise' and 'resilience' in novice and expert anesthesiologists

Anesthesiology is the medical specialty dedicated to the relief of pain and care of the surgical patient before, during and after surgery. Most of the work in anesthesiology is routine patient care, but because patients are sick and surgical procedures may develop in unexpected ways, anesthesiology by its nature often involves medical crises. In recent years, two concepts have gained increasing i

Feasibility of adaptive SBRT of prostate cancer: Investigating uncertainties in AI-driven and CBCT-guided online adaptive radiotherapy

Cancer kan drabba vem som helst och kan ha sitt ursprung i många olika områden i kroppen. Antalet nya cancerfall ökar varje år, men vissa typer av cancer har bättre prognos än andra. Den vanligaste cancertypen i Sverige är prostatacancer och den drabbar framför allt äldre män. Prostatacancer har god prognos och det finns effektiva metoder att helt bota prostat- acancer om den behandlas i ett tidigPurpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB

Analysis of uncoordinated versus coordinated inventory control

This master thesis has been completed at the Faculty of Engineering, Production Management in collaboration with the company Duni Group. The overall objective has been to provide guidance to Duni and analyze how they should control their inventory at each node in their new supply chain set up. The purpose was to determine appropriate reorder points for each location in Duni’s new supply chain setu

Investigating CSF flow in patients with idiopathic normal pressure hydrocephalus using phase-contrast 7T MRI

Idiopatisk normaltryckshydrocephalus (iNPH) är en neurologisk sjukdom som påverkar hjärnans vätskecirkulation och kan leda till symtom som gång- och balanssvårigheter, kognitiv nedsättning och urininkontinens. Sjukdomen drabbar omkring 1.5 % av 70-åringar, och prevalensen ökar med åldern. Det är en svårdiagnostiserad sjukdom där hjärnvätska (CSF) ansamlas i hjärnans hålrum, vilket påverkar hjärnanIntroduction: Idiopathic normal pressure hydrocephalus (iNPH) is a treatable but largely underdiagnosed neurological condition affecting the elderly population. It is characterised by gait and cognitive impairment, as well as urinary incontinence. For the most part, it is diagnosed via imaging and clinical assessments. Abnormalities in cerebrospinal (CSF) flow in the cerebral aqueduct have been li

Psychosocial consequences of false-positive mammography among women attending breast cancer screening. Assessment, prediction, and coping.

Popular Abstract in Swedish Bröstcancer är den vanligaste dödsorsaken bland cancersjuka kvinnor. Därför rekommenderas regelbundna mammografiska hälsokontroller för tidig diagnostik och snar behandling för att förbättra prognosen. I Sverige rekommenderas kontroller för kvinnor mellan 40-74 år. Mammografiska hälsokontroller medför dock även risker, såsom till exempel behov av kompletterande bröstundOne side-effect of breast cancer (BC) screening is a false-positive mammogram among healthy women. That is, finding(s) on a screening mammogram that lead to additional breast examinations but where the woman is eventually considered free from BC. There is evidence of short-term psychosocial consequences of false-positive BC screening. Regarding long-term consequences, research findings are inconsi

Thrombolysis for lower extremity bypass graft occlusion

Background: Thrombolysis is a common method in the treatment of lower extremity bypass graft occlusion. The purpose of this study was to investigate the results of thrombolytic therapy in the management of acute bypass graft occlusion and to identify risk factors for technical failure and amputation. Methods: All patients at two tertiary referral centers undergoing thrombolysis for acute graft occ

Comparison of plasma ALZpath p-Tau217 with Lilly p-Tau217 and p-Tau181 in a neuropathological cohort

There is an urgent need for accurate and validated methods to measure plasma phosphorylated tau (p-Tau) biomarkers in Alzheimer’s disease (AD). In this study, we compared the performance of new commercially available plasma p-Tau217 assay developed by ALZpath to other established p-Tau assays in an autopsy-confirmed sample. We included 72 participants from the Arizona Study of Aging and Neurodegen

Biological mechanisms of resilience to tau pathology in Alzheimer’s disease

Background: In Alzheimer’s disease (AD), the associations between tau pathology and brain atrophy and cognitive decline are well established, but imperfect. We investigate whether cerebrospinal fluid (CSF) biomarkers of biological processes (vascular, synaptic, and axonal integrity, neuroinflammation, neurotrophic factors) explain the disconnection between tau pathology and brain atrophy (brain re

Global, regional, and national burden of stroke and its risk factors, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

Background: Up-to-date estimates of stroke burden and attributable risks and their trends at global, regional, and national levels are essential for evidence-based health care, prevention, and resource allocation planning. We aimed to provide such estimates for the period 1990–2021. Methods: We estimated incidence, prevalence, death, and disability-adjusted life-year (DALY) counts and age-standard

Final simp36 191216

FINAL SIMP36 191216.pdf SIMP36 GRADUATE SCHOOL, FACULTY OF SOCIAL SCIENCES, LUND UNIVERSITY Historical Aspects of Development 
 Version 1.0, January 2020 For an always up-to-date online version, please visit the course site (check regularly for updates) Welcome! SIMP36 Welcome to the Spring term’s course Historical Aspects of Development From a critical historical perspective this course focuses o

https://www.graduateschool.sam.lu.se/sites/graduateschool.sam.lu.se/files/final_simp36_191216.pdf - 2026-06-04

Chemical composition of the Pulp and Seed Kernels of Baobab fruits from three different African Countries

The baobab is among the commonly consumed wild fruits found in the semi-arid regions of sub-Saharan Africa. It has a wide application in food systems and folk medicine and has an advantage of surviving even in harsh environmental conditions. While the fruit pulp is packed with a lot of essential nutrients and has gained much interest in recent past on the international market as a healthy ‘superfo

God man för ensamkommande barn – ett ställföreträdarskap som fyller en god funktion?

Föreliggande uppsats syfte är att undersöka i vad mån svensk rätt tillgodoser asylsökande ensamkommande barns rätt till en ställföreträdare under asylprocessen och vid ett eventuellt beslut om uppehållstillstånd. Uppsatsen tillämpar rättsdogmatisk metod. Syftet besvaras utifrån frågeställningar som ämnar ge svar om vilken rätt som föreligger till en ställföreträdare, vilken funktion den gode manneThe aim with this essay is to investigate how Swedish law accommodate unaccompanied children with a representative during the asylum process and if asylum are approved. Unaccompanied children are defined as children under 18 years of age who have been separated from both parents and are not being cared for by an adult who, by law or custom, is responsible for doing so. International conventions