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Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-year period. Methods: Patients with follow-up and tumor samples, treated between 1990 and 2010, in 93 centers/9 countries. Samples w

Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. Genetic aberrations in the mitogen-activating protein kinase (MAPK) pathway are important in melanoma, of which mutations in BRAF and NRAS are the most common. Additionally, recu

OBJECTIVE: To study intra-aneurysm sac pressure and subsequent abdominal aortic aneurysm (AAA) diameter changes in patients without endoleaks that remain unchanged in AAA diameter more than 1 year after endovascular aneurysm repair (EVAR). METHODS: A total of 23 patients underwent direct intra-aneurysm sac pressure (DISP) measurements 16 months (IQR: 14-35 months) after EVAR. Tip-pressure sensors

SynopsisOptimized structures describing key features of the potential energy surface for water exchange at three planar d8 centers have been calculated using ab initio density functional theory. The local density approximation (LDA), including relativistic corrections for Pt, gives good agreement with the available experimental ground state structural data. LDA binding energies together with expli

The effect of the procedural variability in image acquisition on the quantitative assessment of bone scan is unknown. Here, we have developed and performed preanalytical studies to assess the impact of the variability in scanning speed and in vendor-specific γ-camera on reproducibility and accuracy of the automated bone scan index (BSI). Methods: Two separate preanalytical studies were performed:

Importance: This follow-up study of extremely preterm (EPT) children (<27 weeks' gestational age [GA] at birth) revealed major eye and visual problems in 37.9% (147 of 388) of all EPT infants and in 55.4% (67 of 121) of the most immature subgroups at 6.5 years of age. These major eye and visual problems were strongly associated with treatment-requiring retinopathy of prematurity (ROP).Objectives:

A section of the Swedish library act stipulates that libraries are to pay specific attention to people with disability. Exhaustion syndrome is a mental disability that in recent years has started to grow rapidly in numbers. This master thesis is mainly aiming to study whether public libraries are welcoming and functional places for people with exhaustion syndrome but it also has a wider scope stud

Chromosome defects in high hyperdiploid childhood acute lymphoblastic leukemia Acute lymphoblastic leukemia (ALL) is a type of blood cancer that affects both adults and children. While human cells normally harbor 46 chromosomes, the leukemic cells of the high hyperdiploid subgroup (HeH) of childhood ALL presents 51-67 chromosomes, where the extra chromosomes are generally X, 4, 6, 10, 14, 17, 18

I Sverige vänds omkring 50.000 barns liv upp och ner varje år, när deras föräldrar väljer att gå skilda vägar. Det som en gång varit barnets trygghet och hela värld, rivs upp och känns istället skrämmande och otryggt. Föräldrarnas viljor och känslor styr processen, vilket gör att barnen allt som ofta hamnar i kläm. I en majoritet av fallen löser föräldrarna barnets boende, vårdnad och umgänge gemeIn Sweden the lives of about 50.000 children are turned upside down every year, just because their parents have choosen to separate. What has once been the childs secure and safe world, are now ripped apart and frightening instead. The wills of the parents and their emotions, can greatly impact the decisions of the jucidial process which can in turn have a catasprohic backlash on the child. In the

Internetanvändandet har under de senaste decennierna ökat explosionsartat. Det är något som har lett till att allt fler har valt att göra kommers på att olovligen sprida material som är skyddat av upphovsrätten. När olovligt material sprids via internet kan det vara svårt för rättighetsinnehavaren att nå fram till och få den egentlige intrångsgöraren att sluta med intrånget. Många gånger är det deDuring the last two decades the use of internet has increased enormously. As a result more and more people have started commercialize on transferring information that is protected by copyrights. It is difficult for the owner of the copyright to exam from where the infringement origins. The one that has the best chance to stop an infringement is often the forwarder of the information. This thesis

Föreliggande uppsats är ett examensarbete på juris kandidatprogram. Avhandlingen behandlar de problem som aktualiseras när barn ansöker om bistånd med stöd av 4 kap. 1 §. Inledningsvis kommer jag att ge en kortfattad beskrivning av den sociala barn- och ungdomsvården, det utredningsarbete som förevarit i frågan om barns rätt att ansöka om bistånd samt de internationell principer som den svenska laThe following essay is written within the field of social law. As an introduction the thesis will presents the resent development within the child and youth care system, as well as the international regulations that Swedish legislation must comply with. I will also outline the responsibilities of the government to meet children´s needs for protection and support. Furthermore, the essay will presen

The galloping pace of development in the field of wireless communication has left the world astounded over the last decade. But this has also led to a wild and inexcusable extravagant expenditure of energy. Due to the dynamic nature of wireless network, it has become imperative to focus more on energy efficiency and achieve desired Quality of Service (QoS). The challenge of diminishing the carbon

Over the last couple of decades, the importance of transmission capacity for telecommunications has grown. Enough upgraded, it can be used for both telephony, data transmission, cable TV, provision of movies, and a number of other services. For the provision of all these services, it is absolutely essential to have access to a transmission medium. The existing networks are often built up protected

MAX-lab is a national synchrotron radiation facility in Lund. Nowadays, the MAX project consist of three facilities (three storage rings). A new storage ring is needed to improve material science, such as nanotechnology. MAX IV, also in Lund, will be 100 times more efficient than already existing synchrotron radiation facilities. The storage ring is controlled by a large number of magnets that are

Peak aerobic power in humans ((V) over dot(O2), peak) is markedly affected by inspired O-2 tension (F-IO2). The question to be answered in this study is what factor plays a major role in the limitation of muscle peak. (V) over dot(O2) in hypoxia: arterial O-2 partial pressure (P-a,(O2)) or O-2 content (C-a,C-O2)? Thus, cardiac output (dye dilution with Cardio-green), leg blood flow (thermodilution

Popular Abstract in Swedish Alla levande organismer består av celler som tillsammans med molekyler generellt kallade extracellulär matrix bildar en vävnad. Celler innehåller fyra huvudgrupper av byggstenar: socker, fettsyror, aminosyror och nukleotider, vilka i tur och ordning bildar kolhydrater, fetter, proteiner och nukleinsyror. I vävnaderna pågår en ständig omsättning av byggstenarna och molek

Agricultural intensification in Europe has affected farmland bird populations negatively, both during summer and winter. Although the migratory period poses separate challenges on birds than breeding and wintering, the consequences of farming practices for birds during migration remain poorly investigated. We monitored abundance and species richness of migratory birds in autumn at matched pairs of

Environmental conditions and human activities play a significant role in structuring novel assemblages of native and non-native species. Ongoing and future climatic change may alter the performance of native and non-native species and their biotic interactions. In the northern hemisphere, expected climate changes include warmer temperatures and higher precipitation, the latter of which may increas

Background Despite high incidence of ankle fractures in the elderly, studies evaluating outcome and impact of quality of life in this age group specifically are sparse. The aim of this study was to evaluate outcome and quality of life 6 and 12 months after injury in patients 65 years or older who had been operated on due to an ankle fracture. Methods Sixty patients 65 years or older were invited