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Purpose: In one form of human autosomal recessive retinitis pigmentosa and in retinal degeneration (rd1) mouse, mutation occurs in the genes encoding ß subunit of rod photoreceptor cGMP phosphodiesterase. Therefore, rd1 mutant mouse is an appropriate model for human inherited retinal degeneration studies. Retinal explants are successfully cultured in serum free chemically defined R16 medium to eva
The aim of this thesis is to quantify the consequences of a fire in Kalmar Globals Heavy Electric Forklifts and Electric Reachstackers as well as what actions can be taken to reduce the effects of an ongoing fire and what preventing measures can be made by Kalmar Globals customers to create a safe environment and reduce the probability of a fire breaking out. This thesis builds on information gath
In this work simulations of the LIBAF Pelletron were performed to gain insight into the parameters that govern the machine operation and control. Three simulation packages: COMSOL, WARP and TURTLE/TRANSPORT were employed, and cross-validation of these software packages was performed by test-case simulations. The major components of the Pelletron were simulated on a individual basis to ensure their
Neoliberalism, as a loosely defined set of political beliefs, calls for more individual freedom and autonomy, resulting in increased responsibility for each person to address major societal issues. ‘Individualization’ is the process by which responsibility for addressing major environmental issues such as climate change is placed on individuals. In this thesis I investigate whether individualizati
Variations in molybdenum isotopic composition, spanning the range of similar to 2.3 parts per thousand in the terms of Mo-97/Mo-95 ratio, have been measured in sediment cores from three lakes in northern Sweden and north-western Russia. These variations have been produced by both isotopically variable input of Mo into the lakes due to Mo isotopic heterogeneity of bedrock in the drainage basins and
Background The perception of surgery as expensive and complex might be a barrier to its widespread acceptance in global health efforts. We did a systematic review and analysis of cost-effectiveness studies that assess surgical interventions in low-income and middle-income countries to help quantify the potential value of surgery. Methods We searched Medline for all relevant articles published betw
The purpose of this study was to investigate how volunteers at young women´s and transgender empowerment centers in Sweden reason about their role and their discretion in order to better understand and problematize the responsibility of conducting social work without necessarily holding an education as a social worker. The study focuses on their supportive role in online chats with young callers w
The unbalanced supply and demand will raise the distribution and transportation problems. Lateral transhipment (called stock redistribution) between two Customer Centres (CC) has been implementing to reduce unhealthy inventories. The two significant issues are the inefficient process and unnecessary cost of reactive lateral transhipment. The searching and communication processes can take longer th
Den här kandidatuppsatsen är en kvalitativ studie som undersöker fotboll som arena för integration. Den utgår från teorier om socialt kapital, norm och språk för att kunna analysera och skapa förståelse kring empirin som är hämtad genom fyra intervjuer. Resultatet visar att fotboll har en styrka i att den innehåller ett språk som talas av alla världen över. Men för att fotboll även ska fungera soThis essay is a qualitative study examining football as an arena for integration and the method I’ve used is semi-structured interviews to collect my empirical information. The participants in this study are four different leaders from four different sports associations, which all are different in size and are from different places in Sweden. What they have in common is that they all have experien
In the central Himalayas, water dynamics are expected to change due to multiple factors like climate change, hydro power development and shifting land use practices. This thesis looks at possible changes in water dynamics in Marsyandi river basin, Nepal, as well as causes to those changes and how they are perceived locally. Grounded in critical physical geography, the study uses mixed methods an
Background The colonisation of Australia led to a lot of suffering and sorrow for an uncountable amount of Indigenous people. Due to the forced change of lifestyle and diet during and after the colonisation, conditions like obesity and type 2 diabetes became commonly occurring. Still today there is a higher burden of these conditions, but also of depression and anxiety, in this group of people. Fu
Rostfritt duplexstål är ett konstruktionsmaterial som skulle kunna tänkas vara konkurrenskraftigt i förhållande till konventionella material inom brobyggnad med tanke på dess höga hållfasthet, marginella underhållsbehov och möjlighet till återvinning. Hittills har det dock inte använts i någon större utsträckning inom brobyggnad framför allt på grund av dess högre kostnad i förhållande till traditDuplex stainless steel is a construction material that could possibly prove competitive in relation to conventional materials in bridge design, given its high strength, marginal maintenance needs and the possibility of recycling. To date, however, it has not been used to any great extent in bridge constructions, mainly because of its higher cost in relation to traditional carbon steel. In this stu
Sustainability researchers are facing increasing pressure to improve their scientific communication and to achieve impacts in wider society with their research. Knowledge mobilisation (KMB) is a key component of both challenges, as it relates to efforts undertaken by researchers to achieve impacts with their research. This study seeks to identify some of the KMB practices being undertaken by exper
Klimatförändringar framhålls som vår tids stora ödesfråga. En global temperaturökning kommer att få långtgående och svåröverskådliga effekter på hela världen. I denna uppsats krymps dock perspektivet en aning, och fokuserar på hur klimatförändringarna påverkar det svenska skogsbruket. Genom att betrakta den svenska skogsvårdslagen med tillhörande förordningar och föreskrifter ur ett klimatanpassniClimate change has been considered as the great threat of our time. Global warming will have far-reaching and unwieldy consequences for our planet. The perspective of this essay is a little narrower: The area of investigation in this essay is how climate change will affect the Swedish forestry production. By regarding the Swedish forestry legislation from a climate adaptation perspective, this ess
The maturation of whisky is a long and complex process, the extremely long waiting time causes a large cost for new whisky distilleries, and without sufficient funding, it is hard to start a whisky business. To produce satisfying whisky products within the short term, accelerating the reaction during aging provides a promising approach. Various chemical reactions take place during this stage, this
Growing amounts of waste generation in remote areas without proper waste management systems is a problem to human health and the environment. The Amazon holds the biggest freshwater resources in the world, is a biodiversity hotspot and its communities are placed in distances that can take days by boat to be reached. A National policy with EPR instruments requires private companies to take-back pac
Self-service technology (SST) is implemented in-store as a way of facilitating and enhancing customer experience in which value is co-created. Previous research on SSTs has been mainly conducted in utilitarian settings where discussions were inclined towards attributes of value-in-use with an emphasis on efficiency. However, when implemented in a hedonic retail setting such as fast fashion, co-cre
A shock absorber is used in road vehicles to provide comfortable driving and to optimize the grip. The characteristics are advanced and it takes powerful tools to model a shock absorber. Öhlins Racing AB in Upplands-Väsby is looking for a tool to physically describe their products; in this thesis the task is performed by using the modeling language Modelica and the simulation tool Dymola. The mode
The purpose of the study was to examine how mothers from 30 to 35 years living in a big city felt that stress and status affects their everyday lives and health. My questions was how mothers feel and handling requirements in relation to family life and parenting versus career, the demands on the mothers themselves, and how mothers look at the link between stress and status? I wanted to explore the
