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Identification of novel diagnostic biomarkers for deep venous thrombosis

The combination of a negative D-dimer and a Wells score can rule out, but not confirm, a diagnosis of deep venous thrombosis (DVT). We aimed to identify new diagnostic biomarkers for DVT and to investigate their relationship with hypercoagulability markers [D-dimer and activated protein C-protein C inhibitor (APC-PCI) complex]. We screened 92 cardiovascular-specific proteins in plasma samples from

Styrning genom frivillig koordinering? En studie av europeiska socialfondens genomförande i lokal förvaltning

EU-funding opportunities create incentives for local governments to partake in the implementation of EU regional policies; yet there is a lack of knowledge on the local effects in everyday municipal work. In this article we examine how the European Social Fund (ESF) is used by the EU and national level to govern local activities, how the subnational level acts in response to this and with what con

Sex-based differences in ED management of critically ill patients with sepsis : a nationwide cohort study

Purpose: To compare management and outcomes for critically ill women and men with sepsis in the emergency medical services (EMS), the emergency department (ED) and the ICU. Methods: We used two prospectively compiled Swedish national quality registers, the National Quality Sepsis Registry and the Swedish Intensive Care Registry to identify a nationwide cohort of 2720 adults admitted to an ICU with

Beyond dispersal : the roles of animal movement in modern agricultural landscapes

In this chapter three major concepts relating animal population dynamics to landscape change mediated by animal mobility are outlined: meta-population/community dynamics (affecting many habitat specialists), spillover (affecting e.g. ground-living predators), and landscape complementation (affecting e.g. central-place foragers). It is shown that all three concepts contribute to current understandi

Surviving on the island: linking firm survival and contextual factors in a peripheral region

The lion’s share of entrepreneurship research highlights conditions in core regions, while entrepreneurship in peripheral areas has been less studied. This longitudinal study aims at exploring the interplay between the peripheral contexts of island and archipelago communities and firm outcomes - paying special attention to spatial variations and non-linear temporal dimensions. We focus on the surv

Precision of nanoindentation protocols for measurements of viscoelasticity in cortical and trabecular bone

Abstract in UndeterminedNanoindentation has recently gained attention as a characterization technique for mechanical properties of biological tissues, such as bone, on the sub-micron level. However, optimal methods to characterize viscoelastic properties of bones are yet to be established. This study aimed to compare the time-dependent viscoelastic properties of bone tissue obtained with different

No significant differences between intervention programmes on neck, shoulder and low back pain: A prospective randomized study among home-care personnel

The effects of two different prevention programmes on: (1) reported neck, shoulder and back pain, (2) perceived physical exertion at work and perceived work-related psychosocial factors, were evaluated by questionnaires after 12 and 18 months. Female nursing aides and assistant nurses (n = 282) working in the home-care services, were randomly assigned to one of three groups for: (1) individually d

Report of the First International Workshop on molecular blood group genotyping

The use of molecular genetic technology for blood group typing is becoming routine procedure in many reference laboratories worldwide. A First International Workshop was organized on behalf of the International Society of Blood Transfusion (ISBT) and the International Council for Standardization in Haematology (ICSH). Thirty laboratories that provide a molecular diagnostic service participated in

Risk stratification in cardiac surgery: Algorithms and applications

Popular Abstract in Swedish Inför hjärtkirurgi är bedömning av en patients individuella nytta av och risk vid en hjärtoperation en viktig komponent i utredningen inför operationen. En riskstratifiering innebär att patientens olika riskfaktorer (exempelvis sockersjuka, högt blodtryck, antal tidigare hjärtinfarkter, hjärtfunktion) vägs samman till en sannolikhets-bedömning av risken för en viss händThe aims of this research was to compare different risk score algorithms with regard to their validity to predict 30-day and one-year mortality after open-heart surgery, to evaluate if the preoperative risk stratification model EuroSCORE predicts the different components of resource utilization in cardiac surgery, and to systematically evaluate the accuracy and performance of artificial neural net

First incidence depression in the Lundby Study: A comparison of the two time periods 1947-1972 and 1972-1997.

Background: The Lundby Study is a prospective, longitudinal study on a total population consisting of 3563 subjects during 50 years. This study compares first incidence rates of depression and cumulative probabilities for developing a depression over the two time periods 1947-1972 and 1972-1997. Method: The Lundby Study started in 1947. Follow-ups were carried out in 1957 and in 1972. In 1997 the

Equilibrium sampling through membranes (ESTM) of acidic organic pollutants using hollow fibre modules in continuous steady-state mode.

Hollow fibre (HF) membrane modules were applied in continuous mode for equilibrium sampling through membranes (ESTM) of polar organic pollutants. Phenolic compounds (chlorophenols, cresols and phenol) served as model substances and ESTM was tuned towards the measurement of freely dissolved concentrations (C(free)). HF membrane modules were constructed using thin-walled membrane, 1-m module length

Treatment of the critically ill patient with protein C: Is it worth the cost?

INTRODUCTION: We have shown that low protein C levels predict poor survival up to five years in a general intensive care unit patient material and hypothesize that treatment with protein C is beneficial. The objectives were to calculate costs of protein C treatment, at best-case scenario, per statistical life saved. MATERIALS AND METHODS: Ninety-two patients with deranged global haemostatic tests

How economists understand (or not) the relationship between the real and financial economy

Economists' attempts to understand the relationship between the real and the financial eocnomy, and the impact of the latter on the former, go back to the origins of economics but they have gained renewed strength with the financial crisis of 2008 and the resulting economic crisis. The relationship real-finance is variously portrayed as being non-important, mutually beneficial, or destructive, rea

How accurate are continuum solvation models for drug-like molecules?

We have estimated the hydration free energy for 20 neutral drug-like molecules, as well as for three series of 6-11 inhibitors to avidin, factor Xa, and galectin-3 with four different continuum solvent approaches (the polarised continuum method the Langevin dipole method, the finite-difference solution of the Poisson equation, and the generalised Born method), and several variants of each, giving

Markets for energy efficiency: Exploring the implications of an EU-wide 'Tradable White Certificate' scheme

Recent developments in European energy policy reveal an increasing interest in implementing the so-called ‘Tradable White Certificate’ (TWC) schemes to improve energy efficiency. Based on three evaluation criteria (cost-effectiveness, environmental effectiveness and distributional equity) this paper analyses the implications of implementing a European-wide TWC scheme targeting the household and co

Continuous flow hollow fiber liquid-phase microextraction and monitoring of NSAID pharmaceuticals in a sewage treatment plant effluent

A method for simultaneous extraction and quantification Of four non-steroidal anti-inflammatory drugs (NSAIDs) based on continuous flow hollow fiber liquid-phase microextraction (CFHF-LPME) was developed. The effect of sample flow rate, acceptor flow rate, type of acceptor flow (continuous, semi-continuous or forward-backward), type of supported liquid membrane and sample volume was studied. The e

Decreasing rate of fatty involution at screening mammography

RATIONALE AND OBJECTIVES: This study was performed to document the perceived decrease in fatty involution at screening mammography during the past decade and evaluate the influence of hormone replacement therapy (HRT). MATERIALS AND METHODS: In December 1996, the mammograms of 261 consecutive screening patients with a comparison study obtained 5 years earlier were evaluated, and their breasts were

Reentering Society - An anthropological study of a reentry center, in the United States, for incarcerated people working towards their release

The United States has the highest incarceration rate in the world. The phenomenon of mass incarceration largely confines minorities and people living in poverty. More than 600,000 prisoners are released yearly to face barriers of reentering society. Struggles of finding employment, housing, and being denied social services, due to their criminal record, generate a system where former inmates becom

"De tror att gatorna i Europa är gjorda av guld". En kvalitativ studie om människohandel.

Human trafficking is the third largest illegal source of income, after drugs and weapon. The purpose of this study is to investigate why people fall victims for human trafficking and to study wherein the court of justice discusses the victims social background in their court-­‐‑cases. That is to say, the circumstances that is beyond the borders of Sweden. The essay also highlights how aid organiza

Short-Term Interest Rate Models: An Application of Different Models in Multiple Countries

The purpose of this study is to compare the different short-term interest rate models, and to identify the better model within multiple countries. We selected three different types of data from the United States, the United Kingdom, and New Zealand. We compare the models with the historical data within these three countries, and figure out whether different countries could have their own best mode