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Background Severe exacerbations (SevEx), the typical endpoint when evaluating asthma therapies, may provide incomplete assessment, as it relies on patient perception of disease and physician action. CompEx, a composite outcome that includes SevEx and acute worsening events (AWEs) (evaluated from e-diary entries using deterioration in peak expiratory flow (PEF), reliever medication use and worsenin
Gaming disorder (GD) is an addictive disorder with health and social impacts recognized by the World Health Organization. Although the GD treatment evidence base appear to favor cognitive behavioral therapy (CBT), knowledge of its common practice elements is limited. This systematic review critically evaluates CBT interventions for GD, encompassing individual, group, and mixed approaches, to ident
Considering the unstable condition of water resources in Iran and many other countries in arid and semi-arid regions, groundwater studies are very important. Therefore, the aim of this study is to model groundwater potential by qanat locations as indicators and ten advanced and soft computing models applied to the Beheshtabad Watershed, Iran. Qanat is a man-made underground construction which gath
Ever increasing demand for water resources for different purposes makes it essential to have better understanding and knowledge about water resources. As known, groundwater resources are one of the main water resources especially in countries with arid climatic condition. Thus, this study seeks to provide groundwater potential maps (GPMs) employing new algorithms. Accordingly, this study aims to v
Forest fire is known as an important natural hazard in many countries which causes financial damages and human losses; thus, it is necessary to investigate different aspects of this phenomenon. In this study, performance of four models of linear and quadratic discriminant analysis (LDA and QDA), frequency ratio (FR), and weights-of-evidence (WofE) was investigated to model forest fire susceptibili
Smålands museum, the museum of Småland, is a museum for the county of Kronoberg, a mission given to the museum by the state and county council. The main fields of the museum are the cultural heritage and the history of culture of the region. The museum of Småland is also the Swedish museum of glass. This Master s thesis focuses on the information requirements of the employees at the museum of Smål
This thesis gives a contribution to strategy-proof social choice theory, in which one investigates to what extent there exist voting procedures that never can be manipulated in the sense that some voter by misrepresentation of his preferences can change the outcome of the voting and obtain an alternative he prefers to that honest voting would give. When exactly one element should be elected from a
The purpose of this essay is to acquire variables that explain and may be used as a base for wage estimation in the private sector in Sweden. The factors that are assumed to have an impact on wage estimation are based on earlier Swedish and international studies. Business survey data, which is based upon monthly questions to firms in various sectors of the Swedish economy posed by the Swedish Nati
Adeno-associated viruses (AAVs) are among the most promising vectors for safe and effective gene delivery in therapeutic applications. However, engineering functional AAV capsids remains a major challenge due to the vast sequence space, unpredictable biological performance, and limited translational success of many variants. Machine learning offers a powerful strategy to address these limitations
With the growing integration of renewable energy sources into the power grid, new challenges for system stability have emerged. To address this, the European Union has introduced a regulation called Requirements for Generators (RfG). This regulation sets specific performance standards, one of which is a minimum critical clearing time related to faults. Some production facilities with low inertial
Levels of carbon dioxide (CO2) and other greenhouse gases (GHG) are rising, thereby acceler-ating global warming and related effects on the environment. Forests are an important ecosystem and can act as carbon sinks, providing a buffer against these effects. However, disturbances such as clearcutting can turn the forests into carbon sources. In this project, the effects of clearcutting on the carb
Social workers in Swedish child welfare operate within a context where children’s right to express their views is legally regulated, while professional decision-making often takes place in complex situations involving different perspectives and interests. This study aimed to explore how social workers describe their use of professional discretion in cases where children’s and parents’ wishes do no
The multitaper spectrogram, with arithmetic and geometric mean functions, and the ambiguity domain where evaluated on simulated data and real audio samples{. This was done} to determine if they can improve the results, of classification tasks, of the single-taper spectrogram when used as input to a convolutional neural network. The spectrogram used was differentiable to allow for the window length
This thesis investigates simulating X-ray computed tomography with two primary objectives: developing a virtual representation of an X-ray computed tomography scanner and generating labelled synthetic training data for deep learning-based fibre segmentation. A simulation pipeline to generate X-ray projections based on the Beer-Lambert law was developed using the open-source framework gVirtualXray.
Introduction: The transport sector remains a major contributor to global greenhouse gas emissions, driving demand for engine concepts that eliminate carbon and nitrogen-oxide output while reusing existing manufacturing infrastructure. Background: The Argon Power Cycle is an engine concept that replaces air with argon as a working fluid and uses hydrogen as fuel and oxygen as the oxidizer. By explo
Background: Mistletoe extract is a widespread complementary therapy mainly used for quality-of-life improvement in cancer patients. Advanced pancreatic cancer is associated with poor quality of life and better therapies for symptomatic relief are highly needed. Aim: MISTRAL aimed to assess the impact of mistletoe extract on quality of life, body weight, observed costs and blood biomarkers in patie
During land model development, simulated carbon dynamics are often benchmarked against observational data sets to evaluate model performance. Functional relationship benchmarks are the relationship between a driving variable (e.g., temperature) and a response variable (e.g., ecosystem respiration) and are a promising tool for assessing model performance by evaluating modeled sensitivities to chang
