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In the scientific domain of high energy physics (HEP), the Worldwide LHC Computing Grid (WLCG) was created in order to handle the huge compute and storage needs of the experiments at Large Hadron Collider (LHC). Today WLCG combines about 1.4 million computer cores and 1.5 exabytes of storage from over 170 sites in 42 countries. What ties the sites together is the middleware installed at each site,
Uppsatsen behandlar 1 § femte stycket lagen (1990:52) med särskilda bestämmelser om vård av unga, LVU. Den uttrycker principen om barnets bästa och preciserar den vikt som hänsyn till barnets bästa ges vid tillämpning av LVU. Framställningens huvudsakliga syfte har varit att kartlägga och analysera hur barnets bästa tolkas och tillämpas i mål om beredande samt upphörande av vård enligt LVU. Uppnå
Soil and groundwater contamination is an increasingly recognised threat to public health and the environment around the globe. New types of contaminants continue to emerge, and awareness of their threat, continues to develop. Many countries have national clean-up programs with priority lists of the most hazardous contaminated sites. Investigation and remediation of these sites, however, take a lon
In silico tools for splicing defect prediction have a key role to assess the impact of variants of uncertain significance. Our aim was to evaluate the performance of a set of commonly used splicing in silico tools comparing the predictions against RNA in vitro results. This was done for natural splice sites of clinically relevant genes in hereditary breast/ovarian cancer (HBOC) and Lynch syndrome.
Climate change and human impact play a huge role in the sustainability and development of ecosystems and the services they offer to societies over temporal and spatial scales. Fossil pollen-based estimates provide unique information on past land cover change, but to date there are not many methods able to create spatially continuous maps and have a fine scale of land cover changes inferred from po
På vägen mot en kandidat i historisk arkeologi har Isabella breddat sin utbildning med ett utbytesår i York, England. ”Det bästa med historisk arkeologi är att du får kombinera det praktiska i arkeologi med det teoretiska i historieämnet, och det är särskilt speciellt i en historisk stad som York.”
The chiral tetradentate N4-donor ligand, 1-methyl-2-({(S)-2-[(S)-1-(1-methylbenzimidazol-2-yl methyl)pyrrolidin-2-yl]pyrrolidin-1-yl}methyl) benzimidazole (S,S- PDBz L), based on a chiral dipyrrolidine backbone, has been synthes
Molecularly imprinted nanoparticles are cross-linked polymer colloids containing tailor-made molecular recognition sites. In this study, molecularly imprinted nanoparticles were easily encapsulated within polymer nanofibers using an electrospinning technique to produce a new type of molecular recognition material. Poly(ethylene terephthalate) (PET) was used as the supporting nanofibers matrix to e
Two hydride compounds with aliphatic pincer ligands, (PCyP)IrH2 (PCyP = {cis-1,3-bis[(di-tert-butylphosphino)methyl]cyclohexane}- (1) and (PCyP)IrH4 (2), have been studied, with emphasis on features where such systems differ from arene-based analogues. Both compounds reveal relatively rapid exchange between α-C-H and Ir-H, which can occur via formation of carbene or through demetalation, with near
The production, consumption and disposal of plastics in today’s economies simultaneously contribute to climate change and pollution. With expected production growth for plastics, these problems will only exacerbate. To address the plastic crisis, we need a reduction of its production, as well as a fundamental rethinking of our relationship with this material. Reorganising economies to be less reli
Motivation i Moderna Språk - Aktivitäten zur Visualisierung Schritt 1: Eine Vision schaffen Die Lehrer bitten die Schüler:innen, sich auf die Situation zu konzentrieren, die sie zuvor in dem Text ausführlich beschrieben haben, und sich vorzustellen, dass sie wirklich passiert (bald oder in ein paar Jahren). (Hinweis: Die Schüler:innen dürfen gerne die Augen schließen, um sich die Situation besser
Background: Despite uniform operating techniques, lack of fusion still occurs after ankle arthrodesis. Differences in the biological healing potential may be a factor but the mechanical performance of the arthrodesis construct because of varying bone quality also may be important. Internal compression techniques are preferred because of higher union rates, shorter fusion times, and fewer complicat
Barnets bästa ska vara avgörande i alla mål om vårdnad, boende och umgänge vilket föreskrivs i 6 kap. 2 a § föräldrabalken. Barnets bästa är ingen ny målsättning i svensk rätt utan har funnits sedan många år tillbaka i tiden. Trots det finns det inget allmängiltigt svar på vad barnets bästa är. Anledningen är att barnets bästa är ett levande begrepp som varierar beroende på situation och enskilt b
Anthropogenic N deposition may change soil conditions in forest ecosystems as demonstrated in many studies of coniferous forests, whereas results from deciduous forests are relatively scarce. Therefore the influence of N deposition on several variables was studied in situ in 45 oak-dominated deciduous forests along a N deposition gradient in southern Sweden, where the deposition ranged from 10 to
Purpose: Sustainability is an area of increasing interest for industry and its stakeholders, and some companies now aspire to address sustainability issues (e.g. carbon emissions) at strategic and operational levels. As companies are exploring the issues, they attempt to embed sustainability in their planning and management systems. It is at this point that the domains of environmental concern and
To further improve the flat-type loop heat pipe (LHP) performance, this study evaluates the practical potential of use of highly enhanced boiling structures. It is found that in our proposed new heat pipe (NHP) system, the working fluid from the evaporator outlet to the condenser inlet is in a liquid–vapor two phase flow, which is different from the classical LHP theory. A new P-T diagram is devel
Surface water is vital resources for terrestrial life, while the rapid development of urbanization results in diverse changes in sizes, amounts, and quality of surface water. To accurately extract surface water from remote sensing imagery is very important for water environment conservations and water resource management. In this study, a new Multi-Band Water Index (MBWI) for Landsat 8 Operational
Predicting live birth after the first IVF/ICSI treatment is challenging, as many factors may interactto affect IVF/ICSI outcomes. Adenomyosis is one factor that impacts live birth rates. Machinelearning algorithms have been shown valuable for detecting complex dependencies and predictingoutcomes in different clinical settings. We aimed to develop a prediction model for live birth afterIVF/ICSI trePredicting live birth after the first IVF/ICSI treatment is challenging, as many factors may interact to affect IVF/ICSI outcomes. Adenomyosis is one factor that impacts live birth rates. Machine learning algorithms have been shown valuable for detecting complex dependencies and predicting outcomes in different clinical settings. We aimed to develop a prediction model for live birth after IVF/ICSI
