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Background: Data on the relationship between body mass index (BMI), thromboembolic events (TEE) and bleeding in patients with atrial fibrillation (AF) are controversial, and further evidence on the risk of such events in obese patients with AF receiving different anticoagulant therapies (OAC) is needed. Methods and results: We divided a total of 9330 participants from the prospective PREFER in AF

Asparagine-linked glycosylation 13 homolog (ALG13) encodes a nonredundant, highly conserved, X-linked uridine diphosphate (UDP)-N-acetylglucosaminyltransferase required for the synthesis of lipid linked oligosaccharide precursor and proper N-linked glycosylation. De novo variants in ALG13 underlie a form of early infantile epileptic encephalopathy known as EIEE36, but given its essential role in g

Two-photon excitation laser induced fluorescence (2p-LIF) is used here for imaging through an optically dense spray system. The main advantage of the approach is that a low level of unwanted fluorescence signal originating from multiple-light scattering is generated. This leads to high visibility and image contrast even through scattering media, thus providing faithful descriptions of the imaged f

Existing researches on two-row film cooling mainly focused on double-jet film cooling. However, researches on the effects by combining different kinds of hole shapes on film cooling performance are quite limited. In order to improve the film cooling effectiveness, the three-dimensional numerical method is utilized to investigate the effects of a novel structure composed of two-row holes with diffe

Currently, policy makers in Sweden are considering updating building regulations with respect to daylight provision. Given this context, the present paper aims to provide insight on the level of compliance of residential spaces when tested against five daylight performance criteria. These included the criterion currently in force in Sweden, the two performance criteria set by European Standard EN1

Continuously indexed Gaussian fields (GFs) is the most important ingredient in spatial statistical modelling and geo-statistics. The specification through the covariance function gives an intuitive interpretation of its properties. On the computational side, GFs are hampered with the "big-n" problem, since the cost of factorising dense matrices is cubic in the dimension. Although the computational

Here, we investigated the importance of hormone-sensitive lipase (HSL) as a retinyl ester hydrolase (REH). REH activity was measured in vitro using recombinant HSL and retinyl palmitate. The expression of retinoic acid (RA)-regulated genes and retinoid metabolites were measured in high-fat diet fed HSL-null mice using real-time quantitative PCR and triple-stage liquid chromatography/tandem mass sp

Background. Recent studies have associated the transcription factors, Oct4, Sox2 and Nanog as parts of a self-regulating network which is responsible for maintaining embryonic stem cell properties -- self renewal and pluripotency. In addition, mutual antagonism between two of these and other master regulators have been shown to regulate lineage determination. In particular, an excess of Cdx2 over

PURPOSE: To compare interview data on drug use during pregnancy with data identified from a register of prescriptions. MATERIALS: We compared information from the Swedish Prescribed Drug Register with the Swedish Medical Birth Register on antidepressant use. In order to evaluate the clinical significance of the difference in ascertainment with the two methods, the rate of preterm births among sing

BACKGROUND: To investigate prospectively the patient-relevant outcome 7 years after total hip replacement (THR) for osteoarthritis (OA). METHODS: 219 consecutive patients (120 women) with primary OA, mean age 71 (range 50-92) were assigned for THR. They were examined preoperatively, at 3, 6, 12 months, and at 4, 5 and 7 years postoperatively with the self-administered questionnaires SF-36 and WOMA

Popular Abstract in Swedish Vid blekning av pappersmassa använd i många fall klorinnehållander blekkemikalier. Detta resulterar bildandet av olika klororganiska föreningar som hamnar i avloppsvattnet. Många klororganiska föreningar är giftiga och skadliga för miljön. För att minska utsläppen av dessa föreningar kan avloppsvattnet renas innan det släpps ut. I detta doktorsarbetet har nedbrytningen The microbial decomposition of chlorinated organic compounds in kraft bleaching plant effluent (KBPE) was studied. An aerobic bacterium, Strain TCA1, able to grow on trichloroacetic acid as the sole source of energy and carbon was isolated and characterized. Cultivations of Strain TCA1 and another bacterium, Strain DCA1, on acetic acid and its chlorinated analogues mono-, di-, and trichloroacetic

This thesis is a compilation thesis with the title Young persons at homes for care or residence. On legal security, legitimacy and trust with respect to decisions on young persons in care. The thesis is the result of two research projects within the scope of my research studies at the Faculty of Law, University of Lund, Sweden. The two separate studies share the common theme of the influence of le

Continuously indexed Gaussian fields (GFs) are the most important ingredient in spatial statistical modelling and geostatistics. The specification through the covariance function gives an intuitive interpretation of the field properties. On the computational side, GFs are hampered with the big n problem, since the cost of factorizing dense matrices is cubic in the dimension. Although computational

Gene-lifestyle interactions have been suggested to contribute to the development of type 2 diabetes. Glucose levels 2 h after a standard 75-g glucose challenge are used to diagnose diabetes and are associated with both genetic and lifestyle factors. However, whether these factors interact to determine 2-h glucose levels is unknown. We meta-analyzed single nucleotide polymorphism (SNP) X BMI and SN