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Call the Dependence Thesis the popular view that values are dependent on emotions. This paper argues that the Dependence Thesis is amenable to different readings and critiques one particular reading. According to the Definitional Dependence Thesis, definitions of evaluative concepts necessarily have to appeal to emotions. By contrast, according to the Epistemic Dependence Thesis, which is the targ
Background: The members of the Task Force on Contact Dermatitis and the Task Force on Occupational Dermatoses of the European Academy of Dermatology and Venereology (EADV), of the European Dermatology Forum (EDF), and the members of the UEMS Section of Dermatology-Venereology (UEMS-EBDV) we want to vindicate the fundamental role that the specialist in Dermatology has in the diagnosis and managemen
Introduction Subject movements lead to severe artifacts in magnetic resonance (MR) brain imaging. In this study we evaluate the diagnostic image quality in T1-weighted, T2-weighted, and timeof-flight angiographic MR sequences when using a flexible, navigator-based prospective motion correction system (iMOCO). Methods Five healthy volunteers were scanned during different movement scenarios with and
Objectives To survey renal function in a defined population on metformin treatment. Methods All patients in the city of Malmö who collected at least three prescriptions of metformin during two years were identified from a central registry at the National Board of Health and Welfare in Sweden. Estimated glomerular filtration rate (eGFR), from the Chronic Kidney Disease Epidemiology Collaboration (C
Enzymes were deposited on different porous support materials and these preparations were used to catalyze reactions in organic media. Reactions were carried out at specific water activities, achieved by equilibrating both the enzyme preparation and the substrate solution at the desired water activity before mixing them and thereby starting the reactions. The reaction rates obtained at the same wat
Peptide synthesis was carried out in a variety of organic solvents with low contents of water. The enzyme was deposited on the support material, celite, from an aqueous buffer solution. After evaporation of the water the biocatalyst was suspended in the reaction mixtures. The chymotrypsin-catalyzed reaction between Z-Phe-OMe and Leu-NH2 was used as a model reaction. Under the conditions used ([Z-P
Purpose: To analyze the topography of normal and glaucomatous discs with the goal of developing improved strategies to discriminate between normal and glaucomatous eyes. Subjects and methods: Raster tomography was performed in both eyes of 225 healthy subjects and in 296 eyes of 214 glaucoma patients. Cup area, average cup radius, rim area and minimal rim width were measured in 24 sectors around t
A two-stage polyethylene glycol (PEG)-phosphate aqueous two-phase system was used for purification of a highly thermostable and alkaline active recombinant xylanase. Response surface methodology (RSM) and artificial neural network (ANN) have been used to develop predictive models for simulation and optimization of purification process. Effects of pH, PEG molecular weight, concentrations of phospha
The association between HLA-DQ haplotypes and insulin-dependent diabetes mellitus (IDDM) was studied in 48 children from 44 families ascertained from the high incidence area around Umea, Sweden. Numerous hypotheses have been proposed to explain associations between HLA and IDDM, but comparisons of statistical models based on these hypotheses have not been attempted. The aim of the present study wa
□ Total hip arthroplasty (THA) registers are established in several countries to collect data aiming to improve the results after THA. Monitoring of adverse outcomes after THA has focused mainly on revision surgery, but patientreported outcomes have also been investigated. □ Several surgery-related factors influencing the survival of the THA have been thoroughly investigated and have changed clini
BACKGROUND: Patients with septic shock may undergo extensive physiological alterations that can alter antibiotic pharmacokinetics. OBJECTIVES: To describe the population pharmacokinetics of ciprofloxacin in septic shock and to define recommendations for effective ciprofloxacin dosing in these patients. METHODS: Adult patients with septic shock treated with ciprofloxacin were eligible for inclusion
The aim of this study was to bring to light the meanings attributed to four concepts denoting problematic drinking—“alcoholism,” “alcohol dependence,” “alcohol misuse,” and “risky drinking”—and to investigate whether individuals’ preferences for using these concepts vary depending on their demographic characteristics, their stakeholder group membership, and their own drinking habits. These questio
Background: For up to 50% of adolescents experiencing PTSD, the course of their illness is further complicated by co-occurring substance use. Despite this, evidence-based integrated treatment options for adolescents with this comorbidity remain sparse. To address this gap, we are conducting an RCT examining the efficacy of exposure-based therapy for co-occurring PTSD and substance use among adoles
African economic history has undergone impressive revitalization in the past decade. Much of the recent work is, quite naturally, inspired by developments in economic history at large, and increasingly – indirectly or directly – using markets as the organizing principle in understanding how economies evolve over time. More specifically, recent work assumes that markets create the possibility to us
Objective. Previous research has shown that elderly and disabled travelers using Special Transportation Services (STS) are injured without being involved in a vehicle crash. In order to estimate the true costs for these vehicle-related injuries, the focus needs to be adjusted towards an incident/traveler-oriented perspective. The aim of the project was thus to utilize such a perspective, in order
Background: There is limited evidence regarding the provision of home-based postnatal care, resulting in a weak evidence-base for policy formulation and the further development of home-based postnatal care services. Aim: To explore the structure and organisation of public hospital home-based postnatal care in Victoria, Australia. Methods: An online survey including mostly closed-ended questions wa
Purpose – Scenarios have become a vital methodological approach in business as well as in public policy. When scenarios are used to guide analysis and decision-making, the aim is typically robustness and in this context we argue that two main problems at scenario set level is conservatism, i.e. all scenarios are close to a perceived business-as-usual trajectory and lack of balance in the sense of
Aim: To compare clinical assessments of mental disorders with the Hopkins Symptom Check List-25 (HSCL-25) in a population-based sample consisting of middle-aged and elderly subjects. Background: The Lundby Study is a prospective cohort study that evaluated mental disorders and personality traits in an unselected Swedish population. The study commenced in 1947, with follow-ups in 1957, 1972 and
