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The MLL gene in chromosome band 11q23 is frequently rearranged in acute lymphoblastic and acute myeloid leukemias. To date, more than 50 different chromosomal regions are known to participate in translocations involving 11q23, many of which affect MLL. The pathogenetically important outcome of these rearrangements is most likely the creation of a fusion gene consisting of the 5' part of the MLL ge
Popular Abstract in Swedish Den här avhandlingen är ett bidrag till utvecklingen av en metodik som gör det möjligt att med hjälp av fossila pollen d.v.s. pollen som lagrats i mossar och sjöar, rekonstruera historiska och förhistoriska landskap så precist som möjligt vad gäller utbredning av skog, olika typer av öppen mark samt vegetationens sammansättning. Den tolknings metodik som för närvarande Fossil pollen records retrieved from peat and lake sediments have great potential for quantifying past plant cover. This thesis is a contribution to the development of a palynological interpretation tool for reconstructing past cultural landscapes in terms of plant abundance and distribution. The aims of this thesis are (1) to explore pollen-vegetation relationships in the ancient, traditional cul
Den 16 april 2026 presenterades det nya lagförslaget gällande skärpta regler för unga lagöverträdare i proposition 2025/26:246. I propositionen föreslås bland annat en partiell sänkning av straffbarhetsåldern till 13 år vid allvarlig brottslighet samt införande av ungdomsfängelse för åldersgruppen 13–14 år. Syftet med denna uppsats är att granska argumenten bakom förslaget och hur det förhåller On April 16th, 2026, the new legislative Government bill 2025/25:246 regarding stricter rules for young offenders was presented. The bill proposes a partial lowering of the age of criminal responsibility to 13 for severe crimes, and the introduction of youth imprisonment for the 13–14 age group. The purpose of this thesis is to examine the arguments behind the proposal and compare them with prev
Due to human-induced environmental changes, many natural populations are undergoing extensive fitness declines. Natural or sexual selection could potentially shift the phenotypic mean of critical traits towards new phenotypic optima, promoting evolutionary rescue. However, this process has rarely been studied in natural populations. Furthermore, the population fitness can also be increased by gene
This study aims to investigate how girls within SiS special residential homes for youths are constructed in Swedish news media. The study is based on the social constructivist perspective and Yvonne Hirdman's gender theory. The theory choices have been made to make visible how words in news media construct both gender and the overall image of girls within SiS special residential homes for yout
Artificial intelligence (AI) technologies are being widely employed globally to enhance marine safety services and address challenges within the maritime sector. Nevertheless, the provision of these services in East Africa, particularly within the Lake Victoria basin, is deficient and inadequate. Consequently, a study needs to be undertaken to pinpoint certain domains in marine safety that may be
The terms “gender” and “sex” are central to feminist concerns. In English scholarship “gender” is disputed within and outside of feminism, despite its seemingly political correctness as an alternative to “sex” (Olson 2012; Gunnarsson 2011). This thesis aims to describe how “gender”, multi-word expressions with “gender”, and the derivative “gendered” are translated into Arabic target texts (TTs) by
As one of the primary countries of destination for migrant domestic workers in Asia, Singapore is a developed country with one of the highest standards of living in the region. Yet, the city-state has been on the receiving end of extensive criticism concerning the rights and protections of migrant domestic workers. Civil society organizations have been one of the loudest critics, and in recent pub
Young adult novels about suicide are questioned pieces of literature. Fears of suicide contagion and the perceived unsuitability of such narratives for adolescents lie at the centre of this conflict, which has resulted in the banning of books and other censorship moves. Suicide in literature has been the focus of relatively scarce previous research, and there is a need for further literary critici
Action Research, Participatory Action Research and participatory methods have faced a number of criticisms, including that they do not actually involve citizens or create social change, and that they are tokenistic. This thesis develops and tests a new participatory method that contributes to a democratic and emancipatory PAR that responds to these criticisms and the shortcomings of current method
Chronic respiratory diseases (CRDs) are a group of incurable conditions, among which the most common, such as COPD and asthma, have significant negative impacts on patients’ mental health and economic productivity. Understanding of the causes and affected populations of CRDs is continuously evolving, with air pollution now recognized as an important etiological factor alongside smoking, receiving
The extensive use of neonicotinoids has raised concerns about their impact on pollinators like hoverflies, which are vital for pollination and ecosystem health. This study develops and validates a green extraction method using Supercritical Fluid Extraction (SFE), coupled with HPLC (High Performance Liquid Chromatography) - MS/MS (Mass Spectrometry) for selective analysis. SFE was employed as a m
A search for pair-production of vector-like leptons is presented, considering their decays into a third-generation Standard Model (SM) quark and a vector leptoquark (U1) as predicted by an ultraviolet-complete extension of the SM, referred to as the ‘4321’ model. Given the assumed decay of U1 into third-generation SM fermions, the final state can contain multiple τ-leptons and b-quarks. This searc
BACKGROUND AND PURPOSE: Surgical outcomes in patients with flexible adult-acquired flatfoot deformity (AAFD) have not been evaluated in large prospective register studies. Calcaneal osteotomy and hindfoot arthrodesis are commonly used. We aimed to compare the results of these 2 procedures using preoperative and 1-year postoperative patient-reported outcome data from the Swedish Quality Register fo
Hummeln is a simple impact structure located in south-eastern Sweden. It is approximately 1.2 km in diameter and almost completely covered by a lake. Here, we present the first detailed investigation of impactites and mapping of the 164.25 m deep drill core Hummeln-1 with a focus on impact metamorphism and the impact process. We find that the drilling has penetrated a complex sedimentary successio
We present noble gas analyses of sediment-dispersed extraterrestrial chromite grains recovered from similar to 470 Myr old sediments from two quarries (Hallekis and Thorsberg) and of relict chromites in a coeval fossil meteorite from the Gullhogen quarry, all located ill Southern Sweden. Both the sediment-dispersed grains and the meteorite Gullhogen 001 were generated in the L-chondrite parent bod
