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Technological and policy solutions for transitioning to a fossil-free society exist, many countries could afford the transition, and rational arguments for rapid climate action abound. Yet effective action is still lacking. Dominant policy approaches have failed to generate action at anywhere near the rate, scale or depth needed to avoid potentially catastrophic futures. This is despite 30 years o

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The recent clinical trial (DAWN) suggests that recanalization treatment may be beneficial up to 24 h after stroke onset, thus re-opening avenues for development of new therapeutic strategies. Unfortunately, there is a continuous failure of drugs in clinical trials and one of the major reasons proposed for this translational roadblock is the animal models. Therefore, the purpose of this study was t

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Computed tomography (CT)-derived finite element (FE) models have been proposed as a tool to improve the current clinical assessment of osteoporosis and personalized hip fracture risk by providing an accurate estimate of femoral strength. However, this solution has two main drawbacks, namely: (i) 3D CT images are needed, whereas 2D dual-energy x-ray absorptiometry (DXA) images are more generally av

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Proactive identification of chemicals with skin sensitizing properties is a key toxicological endpoint within chemical safety assessment, as required by legislation for registration of chemicals. In order to meet demands of increased animal welfare and facilitate increased testing efficiency also in nonregulatory settings, considerable efforts have been made to develop nonanimal approaches to repl

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The Amazon rainforests and their biological diversity are being lost rapidly by the onslaught of extractive industries, large-scale agriculture and infrastructure development, which also undermines the integrity of indigenous territories and ethnicities, threatening the tremendous cultural diversity of the Amazon. The loss of forest, the disintegration of local communities and the increase of the

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A search is performed for a heavy particle decaying into different-flavor, dilepton pairs (eμ, eτ or μτ), using 36.1 fb-1 of proton-proton collision data at s=13 TeV collected in 2015-2016 by the ATLAS detector at the Large Hadron Collider. No excesses over the Standard Model predictions are observed. Bayesian lower limits at the 95% credibility level are placed on the mass of a Z′ boson, the mass

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Objectives: To evaluate the effect of preoperative malperfusion on 30-day and late mortality and postoperative complications using data from the Nordic Consortium for Acute Type A Aortic Dissection (ATAAD) registry. Methods: We studied 1159 patients who underwent ATAAD surgery between January 2005 and December 2014 at 8 Nordic centers. Multivariable logistic and Cox regression analyses were perfor

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Multifractal (MF) analysis is used to describe volumes of spatial forms that are formed on the surface of thin layers of ZnxCd1−xTe solid solution grown on the Si (111) substrate. MF analysis is performed on the basis of AFM images of the solid solution surface. The parameters of the MF spectrums for the distribution of volumes of the spatial forms, which formed the surface relief, were found. On

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BACKGROUND: Sacroiliac joint pain is increasingly recognized as a cause of low back pain. We compared the safety and effectiveness of minimally invasive sacroiliac joint arthrodesis using triangular titanium implants and conservative management in patients with chronic sacroiliac joint pain. METHODS: This study was a prospective, multicenter randomized controlled trial of adults with chronic sacro

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Literature investigating highly skilled Chinese migrants has so far focused on their role as drivers of new entrepreneurship as well as innovation in firms and regions, although their role in supporting small and medium enterprises' (SMEs) engagement in global innovation networks (GINs) is still underexplored. The participation in GINs is a key for high-tech SMEs, which rely on sophisticated knowl

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Background: It is unclear to what extent primary care practitioners (PCPs) should retain responsibility for follow-up to ensure that patients are monitored until their symptoms or signs are explained. Aim: To explore the extent to which PCPs retain responsibility for diagnostic follow-up actions across 11 international jurisdictions. Design and setting: A secondary analysis of survey data from the

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Myanmar is endowed with abundant Sn-W mineralization, pre-eminent amongst which is the world-class Mawchi deposit. In the Mawchi area, N-S trending vertical or steeply dipping quartz veins are hosted by both Eocene granite and Carboniferous to Early Permian metasediments. Three stages of ore formation are recognized; (i) tourmaline-cassiterite stage (ii) main ore stage and (iii) sulfide stage. Tou