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Background: Transanal endorectal one-stage pull-through (TERPT) procedure in children with Hirschsprung’s disease (HD) is frequently used worldwide. In order to give the families realistic expectations and to plan the medical care for the years after TERPT, the long term outcome is of great importance. Aim: To collect information on the long term outcome reported after one stage TERPT procedure fo
Objectives To evaluate the real-life effect of an evidence-based Gold Standard Programme (GSP) for smoking cessation interventions in disadvantaged patients and to identify modifiable factors that consistently produce the highest abstinence rates. Design Observational prospective cohort study. Setting GSPs in pharmacies, hospitals and communities in Denmark, reporting to the national Smoking Cessa
We present a search for a light (mass < 2 GeV) boson predicted by Hidden Valley supersymmetric models that decays into a final state consisting of collimated muons or electrons, denoted "lepton-jets". The analysis uses 5 fb(-1) of root s = 7 TeV proton-proton collision data recorded by the ATLAS detector at the Large Hadron Collider to search for the following signatures: single lepton-jets with a
Non-negative matrix factorization (NMF) condenses high-dimensional data into lower-dimensional models subject to the requirement that data can only be added, never subtracted. However, the NMF problem does not have a unique solution, creating a need for additional constraints (regularization constraints) to promote informative solutions. Regularized NMF problems are more complicated than conventio
Diabetes mellitus is one of the most common endocrine disorders in dogs and is commonly proposed to be of autoimmune origin. Although the clinical presentation of human type 1 diabetes (T1D) and canine diabetes are similar, the aetiologies may differ. The aim of this study was to investigate if autoimmune aetiology resembling human T1D is as prevalent in dogs as previously reported.
Background The ankle brachial index (ABI) is related to risk of cardiovascular events independent of the Framingham risk score (FRS). The aim of this study was to develop and evaluate a risk model for cardiovascular events incorporating the ABI and FRS. Design An analysis of participant data from 18 cohorts in which 24,375 men and 20,377 women free of coronary heart disease had ABI measured and w
Cannulation of the papilla vateri represents an enigmatic first step in endoscopic retrograde cholangiopancreaticography (ERCP). In light of falling numbers of (diagnostic) ERCP and novel techniques, e. g. short-wire system, we were interested in the approach novice and experienced endoscopist are taking; especially, what makes a papilla difficult to cannulate and how to approach this. We devised
A bench-scale unit for the development of an enzymatic process for the bioconversion of lignocellulosics to ethanol has been used to study the recycling of waste-water streams to minimize fresh-water requirements and reduce effluent streams. Willow, after impregnation with sulphur dioxide, was steam-pretreated, enzymatically hydrolysed, and the sugars produced were fermented using S. cerevisiae. T
Background-Considerable variability exists in the use of pharmacological thromboprophylaxis among acutely ill medical patients, partly because clinically relevant end points have not been fully assessed in this population. We undertook an international, multicenter, randomized, double-blind, placebo-controlled trial using clinically important outcomes to assess the efficacy and safety of daltepari
This paper concerns the question of how one can frame a political message. I investigate how a political frame is bound both to the line of argumentation connected with a certain discourse and to the audience closely related to that discourse. I have chosen to study a single case where the policy process was characterized by a framing contest. The case shows how negotiating the new Services Direc
The use of a label for locally produced products is seen as a good way of promoting these products in Söderslätt and, thereby, promoting regional development. The only common meaning of the concept ?local? is the reference to a geographical area, even though the size of the area differs. Local products are associated with characteristics such as environment, ethics, health, quality and support of
This master thesis presents a qualitative model for performing a due diligence analysis of non- financial risks and their management, the DANFiRM model. The model includes a thinking process and a working procedure for identifying and evaluating the current non-financial risk exposure at the target enterprise and further required measures for altering risk exposure and risk management activities t
Metals play a key role as a cornerstone of our modern society; they are part of the most basic elements of our daily life and have been part of our lifestyles for millennia. Current trends of metal production point out that developing countries in order to attain a developed-countries consumption level will require 3-9 times the present metal stock per capita, yet their mining practices are far fr
Countries around the world are employing renewable energy policies to increase renewable electricity in their electricity mix. Trinidad and Tobago (T&T), located in the Caribbean, has endogenous sources of oil and natural gas and has not yet capitalised on sources of renewable energy. The country‟s electricity is currently dominantly generated from natural gas however the natural gas reserves
Det här examensarbetet ger en översikt över organiskt material (kerogen) i Jordens yngre lagrade berggrund och hur detta material omvandlats till olja och naturgas genom olika geologiska processer. De viktigaste är tryck, temperatur och tid. Med fortskridande sedimentpålagring förs det organiskt rika sedimenten successivt ned på större djup, där de genomgår en så kallad mognadsprocess till följd aThe origin, composition and maturity of kerogen, and its conversion to petroleum is reviewed. Various methods for estimating the maximum temperature to which kerogen and potential source rocks were subjected are also reviewed. Several kerogen maturation parameters can be distinguished and grouped into two categories: chemical paleothermometres and biological paleothermometres. Biological paleother
The DNA interference pathways exhibited by cisplatin and related anticancer active metal complexes have been extensively studied. Much less is known to what extent RNA interaction pathways may operate in parallel, and perhaps contribute to both antineoplastic activity and toxicity. The present study was designed with the aim of comparing the reactivity of two model systems comprising RNA and DNA h
