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Enteric Helicobacter and H. pylori in chronic inflammation and cancer of the hepatobiliary tract and pancreas

The Helicobacter genus now consists of at least 26 species, with additional novel species in the process of being validated. Beyond the impact of H. pylori and human health, considerable research has focused on other Helicobacter species isolated from humans and animals and the associated natural diseases that range from subclinical inflammation to cancer in the gastrointestinal and hepatobiliary

Protein Dynamics Studied by NMR Spin Relaxation. Conformational Transitions of a Calmodulin Mutant

Binding of calcium to the protein calmodulin leads to molecular reorganization that enables interaction with target peptides and activation of downstream processes. I have studied the dynamics of the calcium-loaded form of a C-terminal calmodulin mutant (E140Q-Tr2C) using NMR spin relaxation experiments. E140Q-Tr2C exhibits global conformational exchange on the microsecond time-scale. The populati

Genomics-driven discovery of novel drug leads in underexplored microorganisms

Underexplored Gram (-) bacteria as a new source of natural products. Microorganisms produce an impressive array of structurally diverse and complex natural products with industrially-important properties. Microbial natural products therefore continue to be an important source of clinical drug candidates. While natural products from a few soil Gram (+) bacteria, together with their biosynthetic pa

Road to Justice: Syrian Gender-Based Violence Survivors and Turkey's International Obligations

Gender-based violence survivors have barriers to access to justice around the globe. However, States are responsible for removing those barriers and ensuring that everyone can access needed services and justice without discrimination regardless of their gender, sexual orientation, race, nationality, disability, or age. Turkey is no exception with its international commitments and domestic laws to

Assessment of Urban Sprawl in Mowe/Ibafo Axis of Ogun State using GIS Capabilities

Urban Sprawl is one of the challenges to urban development in many nations. Different aspects of the phenomenon have been researched with a view to providing solutions to myriad of ills attributed to it. For any meaningful intervention, however, assessment of development to ascertain sprawl is essential. Despite this, its quantification and monitoring in environment with paucity of data remains a

Inventory control of finished goods for the aftermarket.

Background TitanX Engine Cooling is a global supplier of powertrain cooling solutions to commercial vehicles, both for OEMs and the independent aftermarket. The company with annual sales of over 1.6 billion SEK (US$ 192 million) has some 800 employees worldwide. TitanX is headquartered in Gothenburg, Sweden and has manufacturing sites in Sweden, USA, Brazil, China and Mexico. Its manufacturing fac

Inventory control of finished goods for the aftermarket.

Background TitanX Engine Cooling is a global supplier of powertrain cooling solutions to commercial vehicles, both for OEMs and the independent aftermarket. The company with annual sales of over 1.6 billion SEK (US$ 192 million) has some 800 employees worldwide. TitanX is headquartered in Gothenburg, Sweden and has manufacturing sites in Sweden, USA, Brazil, China and Mexico. Its manufacturing fac

Thysells image - en spegelbild av företagets identitet?

Syfte: Syftet med arbetet är att studera Thysells identitet och image för att identifiera eventuella gap i överensstämmelsen mellan dessa begrepp. Vi vill vidare beskriva hur företaget genom positionering kan föra identitet och image närmare varandra. Detta är en förutsättning för att få nöjda och lojala kunder samt förbättra företagets lönsamhet. Metod: Genom att konstruera en lönsamhetskedja, be

Disaster Reduction in Developing Countries - Urban Poverty and Earthquake Vulnerability in Slums

The urban population in developing countries was, in 2005, more than 2.3 billion people, which forms an increase by 7 times comparing to the situation in 1950. This is expected to increase even more, until it reaches 3.9 billion by 2030. A parallel urban growth results in high density cities and informal settlements and the creation of urban slums. Naturally, it is the urban poor who are not able

Detection and identification of anomalies in wireless mesh networks using Principal Component Analysis (PCA)

Anomaly detection is becoming a powerful and necessary component as wireless networks gain popularity. In this paper, we evaluate the efficacy of PCA based anomaly detection for wireless mesh networks (WMN). PCA based method [1] was originally developed for wired networks. Our experiments show that it is possible to detect different types of anomalies, such as Denial-of-service (DoS) attack, port

Diagnostic, prognostic and management aspects of different types of multiple sclerosis

Background: The aim in the thesis is to study diagnostic issues, clinical features, therapy, and prognosis in selected demyelinative disorders of the nervous system: optic neuritis (ON), primary progressive MS (PPMS), and tumefactive MS (a very rare acute demyelinating disorder). Methods: From an initial cohort of 110 patients with ON collected 19 to 31 years ago, a new follow-up survey was cond

From Trade Preferences to Trade Facilitation

Popular Abstract in Swedish Populärvetenskaplig sammanfattning: Det genomgående temat i avhandlingen är hur handeln mellan den Europeiska Unionen (EU) och utvecklingsländer kan öka. Två olika policyalternativ utvärderas: så kallade handelspreferenser samt förenklingar av handelsprocedurer. Handelspreferenser innebär i sin enklaste form att höginkomstländer kräver lägre tullar på importvaror somThe main theme of the thesis is how to increase trade between the European Union (EU) and developing countries. Two available policy options are assessed: trade preferences and trade facilitation. Chapter 1 offers a broad discussion of these policies, and concludes that while trade preferences, which once dominated North-South trade relations, are at a risk of becoming obsolete, trade facilitation

TuFT: Tunnel Fire Tools - Teknisk dokumentation

Inom ramen för det svenska forskningsprojektet Taktik och metodik vid brand i undermarksanläggningar har ett enkelt planeringsverktyg utvecklats som bl a erbjuder stöd till beslutsfattare involverade i planeringen av räddningsinsatser i väg- och järnvägstunnlar. Verktyget, som har utvecklats vid Lunds universitet, heter TuFT och är en förkortning av Tunnel Fire Tools. TuFT kan beskrivas som ett myWithin the Swedish research project Rescue tactics and methodology during fires in underground facilities, a simple decision support tool has been developed. The tool can, for example, aid decision makers involved in the early phase of road and rail tunnel fire risk assessments. The tool has been developed at Lund University and has been termed TuFT, which is an abbreviation for Tunnel Fire Tools.

Cost-effectiveness of surgery and its policy implications for global health: a systematic review and analysis

Background The perception of surgery as expensive and complex might be a barrier to its widespread acceptance in global health efforts. We did a systematic review and analysis of cost-effectiveness studies that assess surgical interventions in low-income and middle-income countries to help quantify the potential value of surgery. Methods We searched Medline for all relevant articles published betw

Vård under tvång eller krav på samtycke? En studie av missbruksvården inom verkställigheten av fängelsestraff

En stor andel av alla brottslingar som kommer i kontakt med den svenska kriminalvården lider av något slags missbruk. Kriminaliteten har ofta ett samband med missbruket och personen kan exempelvis ha begått brottet under någon slags påverkan eller i syfte att anskaffa sig droger. Såväl samhället som den dömde har ett stort intresse av att behandla ett eventuellt missbruk inom ramen för ett fängelsA large percentage of all the criminals who come in contact with the Swedish correctional system suffer from some kind of substance abuse. The criminality is often related to the abuse and the person may have committed such offense under some kind of influence or to obtain the substance. Both society at large and the offender may have a strong interest in the treatment of abuse in connection with