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Validation of standardized creatinine and cystatin C GFR estimating equations in a large multicentre European cohort of children

Background: Most validations of paediatric glomerular filtration rate (GFR) estimating equations using standardized creatinine (CR) and cystatin C (CYS) assays have comprised relatively small cohorts, which makes accuracy across subgroups of GFR, age, body mass index (BMI) and gender uncertain. To overcome this, a large cohort of children referred for GFR determination has been established from se

Quality assurance of texture web materials using cellular neural networks

The paper present a parallel implementation of an image processing algorithm for the on-line, non-destructive quality assurance of the non-woven, fibrous web materials. The task of the algorithm is to compute the material microstructure descriptors. The premise underlying this work is that the microstructure determines the performance of the material and characterization of the microstructure may

A novel method for creatinine adjustment makes the revised Lund–Malmö GFR estimating equation applicable in children

The aim of this study was to establish creatinine growth curves separately for males and females that can be used to adjust childhood levels of serum creatinine to corresponding adult levels. Linear regression with fractional polynomials of age as independent variable was used to construct creatinine growth curves for a reference cohort (n = 83,157 samples from Belgium and Sweden, age 2–40 years).

Insamling av geografiska data

Summary: Geografisk informationsbehandling baseras på insamling, lagring, analys och visualisering av geografiska data. Denna indelning utgör också grunden för bokens disposition. Boken är i första hand avsedd för introducerande kurser vid universitet och högskolor men vissa delar är lämpliga även på avancerad nivå. Den är också utmärkt för yrkesverksamma inom GIS som vill öka sina teoretiska kuns

Night conditions affect morning incubation behaviour differently across a latitudinal gradient

Intermittently incubating birds alternate between sessions of egg warming and recesses for foraging during the day, but stay on the nest continuously at night. Hence, energy costs of nocturnal incubation (which increase during longer and colder nights) cannot be replenished until the next day. Night conditions might therefore be expected to affect morning incubation behaviour the day after. We tes

Direct deposition of gas phase generated aerosol gold nanoparticles into biological fluids - corona formation and particle size shifts.

An ongoing discussion whether traditional toxicological methods are sufficient to evaluate the risks associated with nanoparticle inhalation has led to the emergence of Air-Liquid interface toxicology. As a step in this process, this study explores the evolution of particle characteristics as they move from the airborne state into physiological solution. Airborne gold nanoparticles (AuNP) are gene

Molecular epidemiology of malaria prevalence and parasitaemia in a wild bird population.

Avian malaria (Plasmodium spp.) and other blood parasitic infections of birds constitute increasingly popular model systems in ecological and evolutionary host-parasite studies. Field studies of these parasites commonly use two traits in hypothesis testing: infection status (or prevalence at the population level) and parasitaemia, yet the causes of variation in these traits remain poorly understoo

Implications of accounting for land use in simulations of ecosystem carbon cycling in Africa

Dynamic global vegetation models (DGVMs) are important tools for modelling impacts of global change on ecosystem services. However, most models do not take full account of human land management and land use and land cover changes (LULCCs). We integrated croplands and pasture and their management and natural vegetation recovery and succession following cropland abandonment into the LPJ-GUESS DGVM.

Validation of a Digital Pathology–Based Multimodal Artificial Intelligence Biomarker in a Prospective, Real-World Prostate Cancer Cohort Treated with Prostatectomy

Purpose: A multimodal artificial intelligence (MMAI) biomarker was developed using clinical trial data from North American men with localized prostate cancer treated with definitive radiation, using biopsy digital pathology images and key clinical information (age, PSA, and T-stage) to generate prognostic scores. This study externally validates the biomarker in a prospective, real-world dataset of

Global Price Management – Incentives for Implementing an IT-based Price Management System

Problem discussion: Syncron experience a challenge in realizing the full market potential of its newly developed IT-based price management system, Global Price Management (GPM). The system has already been implemented and is currently running with success within the IT-structures of the first customer. The fact that the development of the system has been initiated by a customer, and thereby has le

Calibration of the carbon isotope composition (δ13C) of benthic foraminifera

The carbon isotope composition (δ13C) of seawater provides valuable insight on ocean circulation, air-sea exchange, the biological pump, and the global carbon cycle and is reflected by the δ13C of foraminifera tests. Here more than 1700 δ13C observations of the benthic foraminifera genus Cibicides from late Holocene sediments (δ13CCibnat) are compiled and compared with newly updated estimates of t

Surveillance of COVID-19 vaccine effectiveness : A real-time case-control study in southern Sweden

The extensive register infrastructure available for coronavirus disease 2019 surveillance in Scania county, Sweden, makes it possible to classify individual cases with respect to hospitalisation and disease severity, stratify on time since last dose and demographic factors, account for prior infection and extract data for population controls automatically. In the present study, we developed a case