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Targeting TUBG1 in RB1-negative tumors

The disruption of microtubule dynamics serves as a pivotal strategy for eliminating tumor cells, despite its accompanying toxicities affecting non-tumor cells. This study investigates the potential of selectively targeting γ-tubulin1 (TUBG1) as a therapeutic strategy in cancer treatment. By elucidating the TUBG1-E2F1-retinoblastoma protein (RB1) network, we introduce a novel compound, 4-(6-((3-Met

An Ethnographic Study Concerning the Implementation of Education on Ageing for Older Adults with Mild Intellectual Disability : The Perspective of the Educators

Despite the fact that longevity in people with intellectual disability has increased at least as much as in the general population, there is a dearth of interventions related to ageing for these older people. Therefore, this study investigated educators' implementation strategies in a new tailor-designed educational intervention with the goal of supporting the process of ageing for people with mil

6c9d645b2c73f52caa77b1d6bdc3fec53dbc48ce BIOC11 2025p1 kursanalys

Kursutvärdering kursnamn Sida 1 av 4 Biologiska institutionen Grund- och avancerad utbildning KURSANALYS Datum 2025-12-16 Kursansvarig: Martin N Andersson Antal studenter: 38 Antal svar: 14 Betyg: 3,8 Kursanalys: ”Human och Zoofysiologi”, ”BIOC11”, Ht25 period 1 Sammanfattning av kursvärderingen Överlag uppskattades kursen av studenterna (3,8p, median 4,0p) även om kursen fick lägre poäng än förra

https://www.lunduniversity.lu.se/sites/www.lunduniversity.lu.se/files/6c9d645b2c73f52caa77b1d6bdc3fec53dbc48ce_BIOC11_2025p1_kursanalys.pdf - 2026-05-28

The structure of allozyme variation in Silene nutans (Caryophyllaceae) in Denmark and in north-western Europe

We used allozymes to investigate the structure of genetic variation in populations of the perennial herb Silene nutans at local (Denmark), regional (Nordic area) and wide (over a 19A degrees latitudinal gradient) geographic scales in north-western Europe. New data from Denmark were combined with data from previously studied Fennoscandian and western populations. We related patterns of nuclear vari

Assessing above-ground woody debris dynamics along a gradient of elevation in Amazonian cloud forests in Peru: balancing above-ground inputs and respiration outputs

Background: Dead biomass, including woody debris (WD), is an important component of the carbon cycle in tropical forests. Aims: This study analyses WD (>2 cm) and other above-ground fluxes in mature tropical forest plots along an elevational gradient (210-3025 m above sea level) in southern Peru. Methods: This work was based on inventories of fine and coarse WD (FWD and CWD, respectively), above-g

Second-hand values and the production of ethical urban markets

We are seeing today an increased interest in ethics, the environment, and social responsibility at the same time as the individual is expected, in different ways, to realize him-/herself through consumption. These interests coincide with the establishment of ethical markets for re-use and second-hand. In this paper we investigate and map out the ethical shopping spaces in Helsingborg, and how thes

Winter respiratory C losses provide explanatory power for net ecosystem productivity

Accurate predictions of net ecosystem productivity (NEPc) of forest ecosystems are essential for climate change decisions and requirements in the context of national forest growth and greenhouse gas inventories. However, drivers and underlying mechanisms determining NEPc (e.g., climate and nutrients) are not entirely understood yet, particularly when considering the influence of past periods. Here

Sop nikon a1rhd confocal v1.4

PowerPoint Presentation LBIC Nikon confocal A1RHD Standard operating procedure Version 1.4 Dec 2019 (1) (2) Turning on/off the system 1. Turn on computer 2. Power on A1 controller 3. Power on lasers by turning the key. 4. Piezo stage controller should always be left on 5. Turn on stage power supply (bottom box) and DIA lamp if bright field is needed 6. Power on microscope, wait until startup seque

https://www.lbic.lu.se/sites/lbic.lu.se/files/sop_nikon_a1rhd_confocal_v1.4.pdf - 2026-05-28

Jb-yeq short version

Untitled © Johan Jönsson, 2009 Your Employeeship Questionnaire A survey of the relationships at your workplace © Johan Jönsson, 2009 Your Employeeship Questionnaire – self assessment Instructions: • Assume that you are engaged in the following 16 situations that are described. • The situations may differ in respect to how things are in your work team, department, and/or unit. Disregard this and re

https://www.psy.lu.se/en/sites/psy.lu.se.en/files/jb-yeq_short_version.pdf - 2026-05-28

Montuenga

C:/Documents and Settings/USUARIO 1/Escritorio/Thesis/Montuenga.dvi Isomer Studies in the f7/2 shell Master of Science Thesis Pedro Montuenga Supervisor: Prof. Dr. Dirk Rudolph Department of Physics Nuclear Structure Group Lund University 2007 2 Contents 1 Introduction 5 2 Theoretical Background 9 2.1 The Nuclear Shell Model . . . . . . . . . . . . . . . . . . . . . . . . . . 9 2.2 Mirror Nuclei .

https://www.particle-nuclear.lu.se/sites/particle-nuclear.lu.se/files/2023-12/Montuenga.pdf - 2026-05-28

Vart arbetsklimat

Vårt arbetsklimat RIKTLINJER FÖR INSTITUTIONEN FÖR PSYKOLOGI RIKTLINJERNA ÄR TILL FÖR ATT KONKRETISERA VAD VI FÖRVÄNTAR OSS AV VARANDRA PÅ VÅR ARBETSPLATS OCH DÄRMED UNDERLÄTTA ATT GE FEEDBACK, UTVÄRDERA KLIMATET I ARBETSGRUPPER OCH GÖRA DET LÄTTARE ATT FÖRBÄTTRA BEMÖTANDE OCH SAMARBETE. 2 VÅRT ARBETSKLIMAT 3VÅRT ARBETSKLIMAT INSTITUTIONEN FÖR PSYKOLOGI SKA KÄNNETECKNAS AV: Positivt arbetsklimat V

https://www.psy.lu.se/sites/psy.lu.se/files/vart_arbetsklimat.pdf - 2026-05-28

Reseberattelse rebecka johannesson poitiers

Microsoft Word - Reseberättelse Rebecka Johannesson Poitiers .docx Rebecka Johannesson – Service Management Retail Min termin som utbytesstudent i Poitiers, ht15 Jag har under 5 månader läst en utbytestermin vid Université de Poitiers i Frankrike. Jag läste vid fakulteten för management, IAE ( instut d’administration des Enterprises). Jag valde att söka till Poitiers av två anledningar, främst vil

https://www.ses.lu.se/sites/ses.lu.se/files/reseberattelse_rebecka_johannesson_poitiers_.pdf - 2026-05-28

Utlysning asg 2017-2018 sve

Microsoft Word - Brevmall, svenska utlysning ASG.doc Pu fendor f ins t i tutet Lund 2016-09-30 Inbjudan att inkomma med förslag till ”Advanced study group” vid Pufendorfinstitutet, 2017 - 2018 Pufendorfinstitutet inbjuder nu till att ansöka om att bilda ”Advanced study group”. Hur föreslår man en Advanced study group för 2017 - 2018? Ett förslag till ”Advanced study group” skall inkomma till insti

https://www.pi.lu.se/sites/pi.lu.se/files/utlysning_asg_2017-2018_sve.pdf - 2026-05-28

Utbud och preferenser på kontorshyresmarknaden i Stockholm CBD

Rapporten behandlar hyresgästens preferenser vid val av lokal inom Stockholm CBD. Detta analyseras i kontrast till vad hyresvärden upplever att hyresgästen efterfrågar. Därtill adderas aspekter så som hyresgästens uppfattning av befintlig lokal och hur deras betalningsviljor har förändrats för ett antal föreslagna åtgärder. Preferenser som valts att undersökas är; närhet till kollektivtrafik, kundThis thesis analyzes the tenants’ preferences in choosing a location to establish a business within Stockholm CBD. The report analyses the difference between the tenants’ preferences and the landlords’ perception of the tenants’ preference. The tenants’ perception of present lease and how the willingness to pay changes for proposed actions were also analyzed. The purpose of the report is to descri

Mining solar and social innovation : exploring social innovation and the conditions that foster it in a Canadian, community-owned renewable energy project

As a primary driver of climate change, energy systems are often affected by the type of “self-perpetuation and lock-in” that characterize so-called ‘wicked problems’. Although it has a relatively clean energy system, Canada still has provinces (e.g. Alberta, Saskatchewan) that possess carbon-intensive power grids, and provinces that have experienced minimal renewable energy development other tha

Ångest som en merit - Att använda personliga erfarenheter av psykisk ohälsa i vårdarbete

Denna studie syftade till att utforska hur personal inom psykiatri och socialpsykiatri upplever (1) att de använder egna erfarenheter av psykisk ohälsa i sitt arbete (2) olika faktorer som påverkar detta användande. Detta undersöktes med hjälp av semistrukturerade intervjuer, vilka analyserades utifrån tematisk analys med utgångspunkt i aletisk hermeneutik. Elva behandlare med varierande yrkestillThe purpose of this study was to explore how staff in mental health care experience (1) using personal experiences of mental ill health in their work (2) different factors affecting this usage. This was explored using semi-structured interviews, which were analyzed using thematic analysis based on aletic hermeneutics. Eleven staff members in various professions were included. The analysis resulted

Socialtjänstens stöd till familjehem ur utvecklingsekologiskt perspektiv - Fallet Linnéa -

The aim of this essay was to investigate how social workers, within chosen Social services districts in the northwest of Skåne, work with children placed in foster care. Our purpose was to investigate the interaction between the child and the foster home from the perspective of the Ecology of Human Development. Our questions were: * How do the social worker prepare the child and the foster home b

Katolsk politisk doktrin och sociallära : religionsfrihet och mänskliga rättigheter

The 18th century witnessed profound changes in the political thinking of Western societies regarding the individual, society and the state. The principle of freedom of religion was confirmed in the American Declaration of Independence in 1776 and in the French Declaration of the Rights of Man and of the Citizen in 1789. A guiding principle was that the civic rights of individuals were not to be de

Det komplexa barnperspektivet - en kvalitativ studie om tillämpning inom individ-och familjeomsorg

The aim of this study was to explain and understand how the child perspective is used in child welfare investigations. The study was based on five interviews with social workers in a municipality in the southern part of Sweden. The main outcome of this study was that the concept child perspective is a multifaceted and complex concept, all the social workers had a different view on the child perspe

Yrkeskunnande och kompetensutveckling i arbetet med vuxna individer med utvecklingsstörning – ett vårdarperspektiv

Since the law of support and service for people with certain disabilities (LSS) was implemented 1994, the carers’ role has changed from «taking care of» to «giving support to» people with intellectual disabilities/autism, but the requirements of knowledge hasn’t been altered. In order to provide appropriate support, carers need both theoretical knowledge and experience of how people with intellect