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There is compelling evidence to suggest that estrogen administration to women of climacteric age reduces subsequent myocardial infarction by some 50%. Accumulating data also suggests estrogens confer substantial protection from stroke. Given this rationale, it is prudent to suggest to regulatory bodies that estrogen treatment would have this indication. Estrogens have other well-defined, and less

The incidence of hip fracture in Sweden is substantially lower in immigrants than in the population born in Sweden. Thus, the use of a FRAXA (R) model in immigrants overestimates the risk of fracture, and the use of country of origin-specific models may be more appropriate. Introduction Age-specific fracture and mortality rates vary between countries so that FRAX tools are country-specific. In the

The glymphatic system is a highly polarized cerebrospinal fluid (CSF) transport system that facilitates the clearance of neurotoxic molecules through a brain-wide network of perivascular pathways. Herein we have mapped the development of the glymphatic system in mice. Perivascular CSF transport first emerges in hippocampus in newborn mice,

Aortoenteric fistula formation is a devastating condition regardless of whether it is primary or secondary (i.e. after previous aneurysm repair) in nature. Patients present with signs and symptoms of gastrointestinal bleeding with or without signs of systemic infection and are often in a very poor clinical condition. Conventional treatment consists of extensive open surgery (extra-anatomical bypas

Abstract: The FIFA World Cup, together with the Summer Olympic Games, are the two events classified as sports mega-events (SMEs), characterized by their global outreach and different types of costs. Within the SME realm, a paradoxical trend can be seen; they show stronger sustainability agendas, yet generate higher social, economic, and environmental costs. The overarching question is their legaci

Within the circular economy, alternatives to fast-fashion include second-hand clothing consumption. The narratives surrounding second-hand clothing have shifted from the stigma of old, dirty, smelly clothing to trendy, sustainable, and bargain items. The environmental benefits of second-hand are realised through the increased use-intensity and avoided production of new garments. However, these ben

Artificial Intelligence in Cardiothoracic Science was funded 2006. Traditionally, medical decisions are based on the combined strength of clinical facts and the experience of the clinician. A growing understanding of the molecular, genetic and biochemical basis of diseases have greatly increased the degree of complexity in medical decision-making. To identify risk factors in medical registers, a nArtificial Intelligence in Cardiothoracic Science was funded 2006. Traditionally, medical decisions are based on the combined strength of clinical facts and the experience of the clinician. A growing understanding of the molecular, genetic and biochemical basis of diseases have greatly increased the degree of complexity in medical decision-making. To identify risk factors in medical registers, a n

Företagsekonomiska institutionen är en av Sveriges ledande miljöer för utbildning och forskning kring det som rör företag och förvaltningars ekonomi. Här bedrivs en aktiv och avancerad forskning inom entreprenörskap, finans, forskningspolitik, marknadsföring, organisation och ledarskap, redovisning och strategi. Företagsekonomi kan både läsas som fristående kurs och tillsammans med andra ämnen inoThe Department of Business Administration is one of the largest departments at Lund University, and is also the largest department of the School of Economics and Management. With its six departments the EQUIS accredited School of Economics and Management offers high quality education and conducts cutting-edge research in all areas related to the private and public economy. The Department of Busin

Genetiskt modifierade T celler, kända som CAR-T celler, fungerar som cancerriktade missiler, utformade för att specifikt lokalisera och eliminera tumörceller. Nuvarande versioner har visat enastående framgång i vissa blodcancerformer, men tyvärr är de ineffektiva i andra cancertyper, såsom solida tumörer och andra blodcancerformer. Denna begränsning härstammar främst från bristen på verkligt canceGenetically modified T cells, known as CAR T cells, function like cancer-targeting missiles, designed to specifically locate and eliminate tumor cells, providing promising prospects for more effective cancer therapies. While current iterations have demonstrated unprecedented success in certain blood cancers, they have proven ineffective in other cancer types, such as solid tumors and various blood