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This is the first report comparing EULAR and national treatment recommendations for PsA patients across Europe, and the first this decade to compare ASAS-EULAR and national treatment recommendations in axSpA patients. An electronic survey was completed from October 2021–April 2022 by rheumatologists in 15 European countries. One and four countries followed all EULAR and ASAS-EULAR recommendations,
This paper reports a search for Higgs boson pair (hh) production in association with a vector boson (WorZ) using 139 fb - 1 of proton–proton collision data at s=13TeV recorded with the ATLAS detector at the Large Hadron Collider. The search is performed in final states in which the vector boson decays leptonically (W→ℓν,Z→ℓℓ,νν with ℓ= e, μ) and the Higgs bosons each decay into a pair of b-quarks.
BackgroundInterventions that are co-created with end-users, and that are informed by behavior change or implementation theories, support implementation in real world settings. However, injury prevention programs for youth athletes have typically been developed by experts with no, or insufficiently described, end-user involvement and without guidance by theories. The aim of the current study was to
While the eddy covariance (EC) technique is a well-established method for measuring water fluxes (i.e., evaporation or 'evapotranspiration’, ET), the measurement is susceptible to many uncertainties. One such issue is the potential underestimation of ET when relative humidity (RH) is high (>70%), due to low-pass filtering with some EC systems. Yet, this underestimation for different types of EC sy
Background. Patients on kidney replacement therapy (KRT) have been identified as a vulnerable group during the coronavirus disease 2019 (COVID-19) pandemic. This study reports the outcomes of COVID-19 in KRT patients in Sweden, a country where patients on KRT were prioritized early in the vaccination campaign. Methods. Patients on KRT between January 2019 and December 2021 in the Swedish Renal Reg
A large number of variants identified through clinical genetic testing in disease susceptibility genes are of uncertain significance (VUS). Following the recommendations of the American College of Medical Genetics and Genomics (ACMG) and Association for Molecular Pathology (AMP), the frequency in case-control datasets (PS4 criterion) can inform their interpretation. We present a novel case-control
When the ecovillage of Toarp was established in the peri-urban landscape of Malmö, Sweden, it was designed with inspiration from the historical regional landscape and its settlement forms. In the launching of the area the past was mirrored as more sustainable than the present. As demonstrated, the historical references in the planned and produced Toarp landscape are however made selectively and ra
Objective: Incisional negative pressure wound therapy (iNPWT) applied over all incisions after lower extremity bypass in the prevention of surgical site infections (SSIs) is unclear. The primary and secondary aims of this study were to investigate if prophylactic iNPWT after the elective lower extremity bypass prevents SSI and other surgical wound complications. Methods: This was a multicenter, pa
The development of lipid nanoparticle (LNP) based therapeutics for delivery of RNA has triggered the advance of new strategies for formulation, such as high throughput microfluidics for precise mixing of components into well-defined particles. In this study, we have characterised the structure of LNPs throughout the formulation process using in situ small angle x-ray scattering in the microfluidic
The Real-World Implementation, Deployment, and Validation of Early Detection Tools and Lifestyle Enhancement (AD-RIDDLE) project, recently launched with the support of the EU Innovative Health Initiative (IHI) public-private partnership and UK Research and Innovation (UKRI), aims to develop, test, and deploy a modular toolbox platform that can reduce existing barriers to the timely detection, and
The solution of multi-field problems and the numerical implementation by means of the finite element method constitute a sophisticated part of the characterisation of industrial processes. A comprehensive implementation framework for such a system of coupled field equations into a non-linear large strain finite element formulation is provided. The procedure is derived for a micromorphic approach i
A key aspect of an attractive and accessible public transport system is that passengers feel safe and secure, not least from a travel chain perspective. The aim of this paper is to provide an increased understanding of triggers for feelings of insecurity and perceptions of safety in relation to public transport, with a special focus on larger public transport nodes in the city of Malmö, Sweden. Th
OBJECTIVE: To systematically evaluate timely reporting of clinical trial results at medical universities and university hospitals in the Nordic countries.STUDY DESIGN AND SETTING: In this cross-sectional study, we included trials (regardless of intervention) registered in the EU Clinical Trials Registry and/or ClinicalTrials.gov, completed 2016-2019, and led by a university with medical faculty or
Background and purpose: There is an urgent need to improve patient-selection to surgical treatment in advanced ovarian cancer as our results showed that cytoreductive surgery was without effect or even detrimental in a yet unknown subgroup of women. With an ageing population, 30% of women with advanced ovarian cancer in Sweden are >75 years. Nevertheless, there are no recommendations on patient-se
Ocean evaporation, represented by latent heat flux (LE), plays a crucial role in global precipitation patterns, water cycle dynamics, and energy exchange processes. However, existing bulk methods for quantifying ocean evaporation are associated with considerable uncertainties. The maximum entropy production (MEP) theory provides a novel framework for estimating surface heat fluxes, but its applica
The KEYNOTE-564 trial showed that adjuvant immune checkpoint inhibitor (ICI) therapy with pembrolizumab, a PD-1 antibody, significantly improved disease-free survival (DFS) and overall (OS) survival in localised clear-cell renal cell carcinoma (RCC) with a high risk of relapse. The TiNivo and CONTACT-03 trials have reported results for subsequent therapy after progression on ICI therapy in the met
The surface of dry or wet asphalt roads reflects partially linearly polarized light, the degree of linear polarization p of which depends on the darkness and roughness of asphalt: the darker and/or the smoother the asphalt, the higher the p of light reflected from it. If the asphalt is sunlit and the direction of view is parallel to the solar-antisolar meridian, then the direction of polarization
