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This paper argues that rules and norms are conceptually distinct: what is norm is not thereby rule, and vice versa. Versions of conflating the two are discussed and an argument for distinction given. Two objections to the argument are responded to. It is accepted that rules and norms are often intimately related. They are so causally, not conceptually: what norms we live by can make a difference t
Atrial fibrillation (AF) is a common disease with a high prevalence in the adult population. Treatment of AF encompasses antiarrhythmic drugs and catheter ablation to reduce symptoms. The aim of this thesis was to study how to best alleviate symptoms of AF in a safe and efficient way comparing pharmacological treatment and the two dominating catheter ablation techniques, cryoballoon (CRYO) ablatio
Background: It has been demonstrated that weight loss improves symptoms in obese subjects with knee osteoarthritis (KOA). A parallel change in cartilage morphology remains to be demonstrated. Purpose: To demonstrate a parallel change in cartilage morphology. Material and Methods: Obese patients with KOA were examined before and after weight loss over 16 weeks. Target knee joints were radiographica
The transfer-appropriate processing (TAP) account holds that episodic memory depends on the overlap between encoding and retrieval processing (e.g., perceptual or conceptual). In the current study, we employed multivariate pattern analysis (MVPA) of electroencephalography to examine the relevance of spontaneously engaged processing during encoding for later retrieval. Participants encoded word-picThe transfer-appropriate processing (TAP) account holds that episodic memory depends on the overlap between encoding and retrieval processing (e.g., perceptual or conceptual). In the current study, we employed multivariate pattern analysis (MVPA) of electroencephalography to examine the relevance of spontaneously engaged processing during encoding for later retrieval. Participants encoded word-pic
Clin Microbiol InfectAbstract The usefulness of spa typing was evaluated in relation to pulsed-field gel electrophoresis (PFGE), as a tool for epidemiological typing of methicillin-resistant Staphylococcus aureus (MRSA) in a low-prevalence region in southern Sweden. Bacterial isolates from 216 MRSA cases, newly identified in 2000-2004, were studied. The isolates were obtained from infected patient
Introduction: Dual mobility cups (DMC) are gaining in popularity, as a method to reduce the risk of dislocation after fracture-related hip arthroplasty. Our aim was to compare revision rate in general, as well as due to dislocation and infection, after DMC and conventional THA due to femoral neck fracture, for each of the two groups of lateral and posterior approach. Materials and Methods: This ob
A search for new particles decaying into a pair of top quarks is performed using proton-proton collision data recorded with the ATLAS detector at the Large Hadron Collider at a center-of-mass energy of s=13 TeV corresponding to an integrated luminosity of 36.1 fb-1. Events consistent with top-quark pair production and the fully hadronic decay mode of the top quarks are selected by requiring multip
INTRODUCTION: Numerous prior studies, even from countries with free access to care, have associated long travel time to care with poor survival in patients with colorectal cancer. METHODS: This is a data-linkage study of all 3718 patients with colorectal cancer, diagnosed between 2007 and 2013 in Northern Sweden, one of the most sparsely populated areas in Europe. Travel time to nearest hospital w
A search for direct pair production of scalar partners of the top quark (top squarks or scalar third-generation up-type leptoquarks) in the all-hadronic tt¯ plus missing transverse momentum final state is presented. The analysis of 139 fb - 1 of s=13 TeV proton–proton collision data collected using the ATLAS detector at the LHC yields no significant excess over the Standard Model background expect
Human rights statements on intersex characteristics distinguish legitimate “medically necessary” interventions from illegitimate normalizing ones. Ironically, this binary classification seems partially grounded in knowledge of anatomy and medical interventions; the very expertise that human rights statements challenge. Here, 23 European health professionals from specialist “disorder of sex developHuman rights statements on intersex characteristics distinguish legitimate “medically necessary” interventions from illegitimate normalizing ones. Ironically, this binary classification seems partially grounded in knowledge of anatomy and medical interventions; the very expertise that human rights statements challenge. Here, 23 European health professionals from specialist “disorder of sex develop
This paper describes a search for beyond the Standard Model decays of the Higgs boson into a pair of new spin-0 particles subsequently decaying into b-quark pairs, H→aa→(bb¯)(bb¯), using proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider at center-of-mass energy s=13 TeV. This search focuses on the range 15 GeV≤ma≤30 GeV, where the decay products are collimat
Searches for scalar leptoquarks pair-produced in proton–proton collisions at s=13 TeV at the Large Hadron Collider are performed by the ATLAS experiment. A data set corresponding to an integrated luminosity of 36.1 fb- 1 is used. Final states containing two electrons or two muons and two or more jets are studied, as are states with one electron or muon, missing transverse momentum and two or more
Aim To present a systematic literature review (SLR) on efficacy, immunogenicity and safety of vaccination in adult patients with autoimmune inflammatory rheumatic diseases (AIIRD), aiming to provide a basis for updating the EULAR evidence-based recommendations. Methods An SLR was performed according to the standard operating procedures for EULAR-endorsed recommendations. Outcome was determined by
A search for a right-handed gauge boson WR, decaying into a boosted right-handed heavy neutrino NR, in the framework of Left-Right Symmetric Models is presented. It is based on data from proton–proton collisions with a centre-of-mass energy of 13 TeV collected by the ATLAS detector at the Large Hadron Collider during the years 2015, 2016 and 2017, corresponding to an integrated luminosity of 80 fb
Objectives: This longitudinal study explores whether the working situation (no change in working hours despite care, reduction of working hours due to care or not working) moderates mental and physical health of informal caregivers of older people with Alzheimer's disease (AD) in Italy. Methods: Data from a sample of 146 caregivers of older people with moderate AD involved in the UP-TECH trial acr
Introduction: A critical and as-yet unmet need in Alzheimer's disease (AD) is the discovery of peripheral small molecule biomarkers. Given that brain pathology precedes clinical symptom onset, we set out to test whether metabolites in blood associated with pathology as indexed by cerebrospinal fluid (CSF) AD biomarkers. Methods: This study analyzed 593 plasma samples selected from the European Med
Background: Neoadjuvant and/or adjuvant treatment has led to an improved survival in patients with resectable gastroesophageal adenocarcinoma (GEAC). Nevertheless, survival rates remain poor and, hence, there is a great need to identify novel treatment strategies and relevant complementary diagnostics. Immunotherapies targeting the PD‐1/PD‐L1 checkpoints have shown promising results, but simultane
This Letter presents a search for a heavy neutral particle decaying into an opposite-sign different-flavor dilepton pair, e(+/-) mu(-/+), e(+/-) tau(-/+), or mu(+/-) tau(-/+) using 20.3 fb(-1) of pp collision data at root s = 8 TeV collected by the ATLAS detector at the LHC. The numbers of observed candidate events are compatible with the standard model expectations. Limits are set on the cross se
This paper presents a search for pair production of higgsinos, the supersymmetric partners of the Higgs bosons, in scenarios with gauge-mediated supersymmetry breaking. Each higgsino is assumed to decay into a Higgs boson and a nearly massless gravitino. The search targets events where each Higgs boson decays into Formula Presented, leading to a reconstructed final state with at least three energe
